Patents by Inventor Simon Foote

Simon Foote has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for determining the likelihood that a test polynucleotide sequence differs from a driver polynucleotide
    Patent number: 8666669
    Abstract: The present invention relates generally is a method for determining the likelihood that a test polynucleotide sequence differs from a driver polynucleotide sequence. More particularly, the present method uses fluorescence-based technology in the assessment of the results of competitive hybridization between polynucleotide sequences. The present method does not require nucleotide sequencing or gel electrophoresis and is capable of being multiplexed and automated. The methods of the present invention will find broad application in the analysis of polynucleotides, inter alia in genetic analysis, specific locus testing, genotyping, mutation detection, the discovery and detection of single nucleotide polymorphisms (SNPs) and mapping.
    Type: Grant
    Filed: May 29, 2001
    Date of Patent: March 4, 2014
    Assignee: Genera Biosystems Limited
    Inventors: Karl Poetter, Simon Foote
  • Nucleic acid diagnostics based on mass spectrometry or mass separation and base specific cleavage
    Patent number: 6994960
    Abstract: A method of detecting a mutation or a difference of one or more nucleotides between a nucleic acid molecule to be tested and a reference nucleic acid molecule, said method comprising subjecting the test nucleic acid molecule to base specific cleavage to generate oligonucleotide fragments, separating the resulting oligonucleotide fragments based on mass by MALDI-ATOF MS and/or other equivalent procedure to produce a fingerprint of then oligonucleotide fragments comprising one or more peaks wherein a peak represents the mass of each fragment and identifying an altered peak relative to a reference nucleic acid molecule subjected to the same procedure wherein the presence of an altered peak is indicative of a difference of one or more nucleotides in said tested nucleic acid molecule.
    Type: Grant
    Filed: May 28, 1998
    Date of Patent: February 7, 2006
    Assignee: The Walter and Eliza Hall Institute of Medical Research
    Inventors: Simon Foote, Colleen Elso, Richard Simpson, Gavin Reid
  • Method for determining the likelihood that a test polynucleotide sequence differs from a driver polynucleotide
    Publication number: 20040014065
    Abstract: The present invention relates generally is a method for determining the likelihood that a test polynucleotide sequence differs from a driver polynucleotide sequence. More particularly, the present method uses fluorescence-based technology in the assessment of the results of competitive hybridization between polynucleotide sequences. The present method does not require nucleotide sequencing or gel electrophoresis and is capable of being multiplexed and automated. The methods of the present invention will find broad application in the analysis of polynucleotides, inter alia in genetic analysis, specific locus testing, genotyping, mutation detection, the discovery and detection of single nucleotide polymorphisms (SNPs) and mapping.
    Type: Application
    Filed: May 19, 2003
    Publication date: January 22, 2004
    Inventors: Karl Poetter, Simon Foote