Patents by Inventor Simon G. Stone
Simon G. Stone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11773496Abstract: Electrolytic gas generator and multi-functional current collector for use in same. In one embodiment, the current collector is constructed both to conduct current from an electrode to a conductive lead and to conduct gas generated at the electrode to external tubing. Accordingly, the current collector may be formed by bonding together a top metal plate and a bottom metal plate of similar profiles, each of which may be shaped to include a main portion and a lateral extension. The bottom metal plate may have central through hole in the main portion for receiving gas from the anode. The top metal plate may have a recess on its bottom surface. The recess may have a first end aligned with the through hole on the bottom metal plate and may have a second end at the end of the lateral extension. A lead and tubing may be attached to the lateral extension.Type: GrantFiled: May 17, 2019Date of Patent: October 3, 2023Assignee: GINER, INC.Inventors: Melissa N. Schwenk, Simon G. Stone
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Patent number: 11642501Abstract: Implantable gas delivery device and methods, systems, and devices including same. According to one embodiment, the implantable gas delivery device includes a porous core that permits facile transport of gas throughout its open volume. The porous core has sufficiently high tensile strength to withstand pressurization without significant deformation. The porous core is generally planar and is shaped to include a pair of opposing surfaces and a periphery. Diffusion membranes are fixed to the two opposing surfaces of the porous core. A gas supply tube has one end inserted into the porous core and another end connectable to a gas source. The periphery of the porous core is sealed gas-tight, either with a gasket or by sealing the porous core and/or diffusion membranes. The device may be used to deliver a gas to an implanted cell capsule or to native cells or tissues or may be used to expel waste gas.Type: GrantFiled: May 4, 2018Date of Patent: May 9, 2023Assignee: GINER, INC.Inventors: Anthony A. Ferrante, Simon G. Stone
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Publication number: 20220152369Abstract: Wearable system and method for gas delivery to the exterior surface of an eye. In one embodiment, the system may include a gas source and a wearable gas delivery device. The gas source may include a housing, one or more electrochemical gas generating devices positioned within the housing, and a control unit for controlling the operation of the one or more electrochemical gas generating devices. The one or more electrochemical gas generating devices may include an electrochemical oxygen concentrator and a water electrolyzer. Oxygen outputted from the electrochemical oxygen concentrator may be combined with oxygen and/or hydrogen outputted from the electrolyzer to produce a therapeutic gas having an enriched oxygen concentration and a hydrogen concentration less than 4%. The wearable gas delivery device, which is fluidly coupled to the gas source, may be worn over the eye and may be used to deliver the therapeutic gas to the eye.Type: ApplicationFiled: November 18, 2021Publication date: May 19, 2022Inventors: Melissa N. Schwenk, Douglas W. Lawrence, Simon G. Stone, Griffin James Marella, Linda A. Tempelman
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Publication number: 20220054318Abstract: System and method for modification of fluid environment of an ear. In one embodiment, the system includes an earpiece mountable within an ear canal. The earpiece includes a fluid delivery path for fluid to be delivered to the ear and a fluid removal path for fluid to be removed from the ear. The system also includes an electronics housing. The electronics housing may be directly mounted on the earpiece or positioned outside the ear. The system further includes an electrochemical gas generating device positioned within the electronics housing. In use, oxygen or the like is generated by the electrochemical gas generating device and is conveyed through the fluid delivery path of the earpiece, emerging from the earpiece distal end. The gas released from the earpiece causes fluid in the ear to be swept into the fluid removal path of the earpiece and eventually expelled to the outside of the ear.Type: ApplicationFiled: August 21, 2021Publication date: February 24, 2022Inventors: Melissa N. Schwenk, Ernesto Victor Ruiz, Simon G. Stone, Linda A. Tempelman
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Patent number: 11033666Abstract: Percutaneous gas diffusion device. In one embodiment, the percutaneous gas diffusion device includes a core layer, an outer layer, and an intermediate layer. The core layer may be cylindrical and may include a gas-permeable, liquid-impermeable material. The outer layer may peripherally surround the core layer and may include a tissue-integrating material. The intermediate layer may peripherally surround the core layer and may be peripherally surrounded by the outer layer. The intermediate layer may include a barrier that prevents infiltration of tissue from the outer layer into the core layer and that additionally reduces diffusion of gas from the core layer into the outer layer. The percutaneous gas diffusion device may be coupled to a subcutaneous implant device, such as a subcutaneous container holding implanted cells and/or tissue, a subcutaneous electrochemical oxygen concentrator, or a water electrolyzer.Type: GrantFiled: November 15, 2017Date of Patent: June 15, 2021Assignee: GINER LIFE SCIENCES, INC.Inventors: Anthony A. Ferrante, Simon G. Stone
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Publication number: 20200348113Abstract: Self-regulating electrolytic gas generator and implant system including the same. In one embodiment, the electrolytic gas generator is a water electrolyzer and includes a polymer electrolyte membrane with an anode on one side and a cathode on the other side. Anode and cathode seals surround the peripheries of the anode and cathode and include inlets for water and outlets for oxygen and hydrogen, respectively. A cathode current collector is placed in contact with the cathode, and an anode current collector, which may be an elastic, electrically-conductive diaphragm, is positioned proximate to the anode. The anode current collector is reversibly deformable between a first state in which it is in direct physical and electrical contact with the anode and a second state in which it distends, due to gas pressure generated at the anode, so that it is not in physical or electrical contact with the anode, causing electrolysis to cease.Type: ApplicationFiled: January 6, 2020Publication date: November 5, 2020Inventors: Simon G. Stone, Linda A. Tempelman, Melissa Schwenk
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Patent number: 10557691Abstract: Self-regulating electrolytic gas generator and implant system including the same. In one embodiment, the electrolytic gas generator is a water electrolyzer and includes a polymer electrolyte membrane with an anode on one side and a cathode on the other side. Anode and cathode seals surround the peripheries of the anode and cathode and include inlets for water and outlets for oxygen and hydrogen, respectively. A cathode current collector is placed in contact with the cathode, and an anode current collector, which may be an elastic, electrically-conductive diaphragm, is positioned proximate to the anode. The anode current collector is reversibly deformable between a first state in which it is in direct physical and electrical contact with the anode and a second state in which it distends, due to gas pressure generated at the anode, so that it is not in physical or electrical contact with the anode, causing electrolysis to cease.Type: GrantFiled: November 15, 2017Date of Patent: February 11, 2020Assignee: GINER LIFE SCIENCES, INC.Inventors: Simon G. Stone, Linda A. Tempelman, Melissa Schwenk
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Publication number: 20190368056Abstract: Electrolytic gas generator and multi-functional current collector for use in same. In one embodiment, the current collector is constructed both to conduct current from an electrode to a conductive lead and to conduct gas generated at the electrode to external tubing. Accordingly, the current collector may be formed by bonding together a top metal plate and a bottom metal plate of similar profiles, each of which may be shaped to include a main portion and a lateral extension. The bottom metal plate may have central through hole in the main portion for receiving gas from the anode. The top metal plate may have a recess on its bottom surface. The recess may have a first end aligned with the through hole on the bottom metal plate and may have a second end at the end of the lateral extension. A lead and tubing may be attached to the lateral extension.Type: ApplicationFiled: May 17, 2019Publication date: December 5, 2019Inventors: Melissa N. Schwenk, Simon G. Stone
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Publication number: 20190343616Abstract: Method and system for controlling oxygen delivery to a cell implant. In one embodiment, the system includes a water electrolyzer, a cell capsule, a gas conduit, a total fluid pressure sensor, and a controller. The water electrolyzer generates gaseous oxygen with a variable output. The cell capsule includes a cell chamber adapted to hold cells. The gas conduit interconnects the water electrolyzer and the cell capsule to deliver gaseous oxygen generated by the water electrolyzer to the cell capsule. The total fluid pressure sensor is positioned at a location that provides a representative reading of the total fluid pressure within the cell chamber. The controller is electrically coupled both to the total fluid pressure sensor and to the water electrolyzer so that the controller may control the variable output of the water electrolyzer based on one or more sensed total pressure readings from the total fluid pressure sensor.Type: ApplicationFiled: May 14, 2019Publication date: November 14, 2019Inventor: Simon G. Stone
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Publication number: 20180318566Abstract: Implantable gas delivery device and methods, systems, and devices including same. According to one embodiment, the implantable gas delivery device includes a porous core that permits facile transport of gas throughout its open volume. The porous core has sufficiently high tensile strength to withstand pressurization without significant deformation. The porous core is generally planar and is shaped to include a pair of opposing surfaces and a periphery. Diffusion membranes are fixed to the two opposing surfaces of the porous core. A gas supply tube has one end inserted into the porous core and another end connectable to a gas source. The periphery of the porous core is sealed gas-tight, either with a gasket or by sealing the porous core and/or diffusion membranes. The device may be used to deliver a gas to an implanted cell capsule or to native cells or tissues or may be used to expel waste gas.Type: ApplicationFiled: May 4, 2018Publication date: November 8, 2018Inventors: Anthony A. Ferrante, Simon G. Stone
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Patent number: 10091985Abstract: Method and system for organ preservation. According to one aspect, an organ may be preserved by being perfused with an in situ generated preserving gas. The organ may be, for example, a human or porcine pancreas, and perfusion of the pancreas may be anterograde, retrograde, ductal, anterograde/ductal, or retrograde/ductal. The preserving gas used to perfuse the organ may be dissolved in a liquid and then administered to the organ as a gas/liquid solution or may be mixed with one or more other gases and then administered to the organ as a gas/gas mixture. The preserving gas may be, for example, oxygen gas generated in situ using an electrochemical oxygen concentrator. According to another aspect, an organ preservation system may include an electrochemical oxygen concentrator having a water vapor feed, as well as auxiliary equipment to control and measure delivery pressure, flow, temperature and humidity.Type: GrantFiled: June 18, 2010Date of Patent: October 9, 2018Assignee: GINER, INC.Inventors: Linda A. Tempelman, Klearchos K. Papas, Simon G. Stone, William Earl Scott, III, Thomas M. Suszynski, Shuichiro Matsumoto, Joana Ferrer Fabrega, Michael D. Rizzari
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Publication number: 20180133383Abstract: Percutaneous gas diffusion device. In one embodiment, the percutaneous gas diffusion device includes a core layer, an outer layer, and an intermediate layer. The core layer may be cylindrical and may include a gas-permeable, liquid-impermeable material. The outer layer may peripherally surround the core layer and may include a tissue-integrating material. The intermediate layer may peripherally surround the core layer and may be peripherally surrounded by the outer layer. The intermediate layer may include a barrier that prevents infiltration of tissue from the outer layer into the core layer and that additionally reduces diffusion of gas from the core layer into the outer layer. The percutaneous gas diffusion device may be coupled to a subcutaneous implant device, such as a subcutaneous container holding implanted cells and/or tissue, a subcutaneous electrochemical oxygen concentrator, or a water electrolyzer.Type: ApplicationFiled: November 15, 2017Publication date: May 17, 2018Inventors: Anthony A. Ferrante, Simon G. Stone
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Publication number: 20180135948Abstract: Self-regulating electrolytic gas generator and implant system including the same. In one embodiment, the electrolytic gas generator is a water electrolyzer and includes a polymer electrolyte membrane with an anode on one side and a cathode on the other side. Anode and cathode seals surround the peripheries of the anode and cathode and include inlets for water and outlets for oxygen and hydrogen, respectively. A cathode current collector is placed in contact with the cathode, and an anode current collector, which may be an elastic, electrically-conductive diaphragm, is positioned proximate to the anode. The anode current collector is reversibly deformable between a first state in which it is in direct physical and electrical contact with the anode and a second state in which it distends, due to gas pressure generated at the anode, so that it is not in physical or electrical contact with the anode, causing electrolysis to cease.Type: ApplicationFiled: November 15, 2017Publication date: May 17, 2018Inventors: Simon G. Stone, Linda A. Tempelman, Melissa Schwenk
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Patent number: 9357764Abstract: System for fluid perfusion of biological matter that includes tissue. According to one embodiment, the system may include a storage container for storing the biological matter, a thermal control device for cooling the contents of the storage container, a gas generator for generating a preserving gas, a fluid conduit coupled to the gas generator and insertable into tissue for delivering the preserving gas to the biological matter, and a process controller for controlling the operation of the gas generator and the thermal control device. The gas generator, in turn, may include an electrochemical oxygen concentrator and/or a water electrolyzer for generating the preserving gas. The system may further include a liquid perfusion system that includes a reservoir of liquid perfusate, a fluid delivery conduit for delivering liquid perfusate from the reservoir to the biological matter, and a fluid draining conduit for draining liquid perfusate from the biological matter.Type: GrantFiled: December 30, 2011Date of Patent: June 7, 2016Assignee: GINER, INC.Inventors: Linda A. Tempelman, Simon G. Stone
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Publication number: 20120178150Abstract: System for fluid perfusion of biological matter that includes tissue. According to one embodiment, the system may include a storage container for storing the biological matter, a thermal control device for cooling the contents of the storage container, a gas generator for generating a preserving gas, a fluid conduit coupled to the gas generator and insertable into tissue for delivering the preserving gas to the biological matter, and a process controller for controlling the operation of the gas generator and the thermal control device. The gas generator, in turn, may include an electrochemical oxygen concentrator and/or a water electrolyzer for generating the preserving gas. The system may further include a liquid perfusion system that includes a reservoir of liquid perfusate, a fluid delivery conduit for delivering liquid perfusate from the reservoir to the biological matter, and a fluid draining conduit for draining liquid perfusate from the biological matter.Type: ApplicationFiled: December 30, 2011Publication date: July 12, 2012Inventors: Linda A. Tempelman, Simon G. Stone
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Publication number: 20110097678Abstract: Method of heating and heating apparatus. According to one embodiment, the heating apparatus is designed for warming infusion fluids and includes a pair of catalytic heaters positioned around a cartridge containing the infusion fluid. Each catalytic heater includes a pair of frames jointly defining a cavity. One of the frames per heater is positioned proximate to the cartridge and includes an input port for receiving a liquid solution of methanol. The other frame per heater is positioned distal to the cartridge and includes an input port for receiving oxygen gas and an output port for exhaust gases. A first fluid diffusion medium is positioned within the methanol frame, and a second fluid diffusion medium is positioned within the oxygen frame. Sandwiched between the two diffusion media are a pervaporation membrane facing the first diffusion medium and a porous metal catalyst facing the second diffusion medium.Type: ApplicationFiled: October 5, 2010Publication date: April 28, 2011Inventors: Keith D. Patch, Linda A. Tempelman, Simon G. Stone, Craig Thompson
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Publication number: 20100330547Abstract: Method and system for organ preservation. According to one aspect, an organ may be preserved by being perfused with an in situ generated preserving gas. The organ may be, for example, a human or porcine pancreas, and perfusion of the pancreas may be anterograde, retrograde, ductal, anterograde/ductal, or retrograde/ductal. The preserving gas used to perfuse the organ may be dissolved in a liquid and then administered to the organ as a gas/liquid solution or may be mixed with one or more other gases and then administered to the organ as a gas/gas mixture. The preserving gas may be, for example, oxygen gas generated in situ using an electrochemical oxygen concentrator. According to another aspect, an organ preservation system may include an electrochemical oxygen concentrator having a water vapor feed, as well as auxiliary equipment to control and measure delivery pressure, flow, temperature and humidity.Type: ApplicationFiled: June 18, 2010Publication date: December 30, 2010Inventors: Linda A. Tempelman, Klearchos K. Papas, Simon G. Stone, William Earl Scott, III, Thomas M. Suszynski, Shuichiro Matsumoto, Joana Ferrer Fabrega, Michael D. Rizzari
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Publication number: 20090045073Abstract: Electrolysis cell and method of using the same in hydrogen generation. According to one embodiment, the electrolysis cell includes a frame having an interior. A proton exchange membrane (PEM) is disposed within the frame to divide the interior into two chambers. An anode in the form of a gas diffusion electrode is disposed within the interior of the frame and is spaced apart from the PEM, the space between the anode and the PEM being filled with an aqueous sulfuric acid. A cathode is disposed within the interior of the frame and is ionically coupled to the PEM. In use, gaseous sulfur dioxide is delivered to the side of the anode facing away from the sulfuric acid solution, and a current is supplied to the electrolysis cell. Consequently, sulfur dioxide is oxidized at the anode, and molecular hydrogen is generated at the cathode.Type: ApplicationFiled: August 1, 2008Publication date: February 19, 2009Inventors: Simon G. Stone, Lawrence J. Gestaut
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Patent number: 6811905Abstract: A fuel cell and method using the same. The fuel cell comprises a membrane electrode assembly, the membrane electrode assembly comprising a proton exchange membrane having a front face and a rear face. An anode is coupled to the front face of the proton exchange membrane, and a cathode is coupled to the rear face of the proton exchange membrane. A vapor diffusion chamber is positioned in the front of the anode, and a vapor transport member is positioned in front of the vapor diffusion chamber. The vapor transport member is substantially impermeable to an organic fuel/water mixture in a liquid phase but is permeable to the organic fuel/water mixture in a vapor phase. In operation, a liquid fuel mixture delivered to the vapor transport member evaporates from the vapor transport member and is delivered to the anode in vapor form.Type: GrantFiled: May 21, 2002Date of Patent: November 2, 2004Assignee: Giner Electro Chemical Systems, LLCInventors: Cecelia C. Cropley, Simon G. Stone