Patents by Inventor Simon GIRARD

Simon GIRARD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF CULLIN 3 ADAPTOR KBTBD4 AS ANTI-CANCER COMPOUNDS
    Publication number: 20230073512
    Abstract: It is provided the use of Pyrimido[4,5-B]indole derivatives as anti-cancer compounds, and more specifically the use of UM171 and its derivatives for treating cancer, by activating the CULLIN3-RING ubiquitin ligase complex which degrades RCOR1 which normally acts as the scaffolding protein for the RCOR1/LSD1 and HDAC2 complex, itself being dissociated in the presence of UM171. Thus UM171 acts like a molecular glue degrader, inhibiting HDACs, RCOR1, CoREST and LSD1 and resulting in an anti-cancer activity.
    Type: Application
    Filed: December 18, 2020
    Publication date: March 9, 2023
    Inventors: Guy SAUVAGEAU, Jalila CHAGRAOUI, Simon FORTIER, Simon GIRARD, Anne MARINIER
  • Method for the preparation of metal-organic compounds
    Patent number: 10099203
    Abstract: A method for the preparation of a metal-organic compound is provided. This method comprises the steps of (a) providing at least one metal precursor, (b) providing at least one bridging organic ligand, and (c) exposing together the metal precursor and the ligand to liquid CO2 or supercritical CO2 as a reaction medium, thereby producing said metal-organic compound.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: October 16, 2018
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Tomislav Friscic, Chao-Jun Li, Simon Girard, Cristina Mottillo, Christopher Walter Nickels
  • METHOD FOR THE PREPARATION OF METAL-ORGANIC COMPOUNDS
    Publication number: 20180043330
    Abstract: A method for the preparation of a metal-organic compound is provided. This method comprises the steps of (a) providing at least one metal precursor, (b) providing at least one bridging organic ligand, and (c) exposing together the metal precursor and the ligand to liquid CO2 or supercritical CO2 as a reaction medium, thereby producing said metal-organic compound.
    Type: Application
    Filed: February 22, 2016
    Publication date: February 15, 2018
    Inventors: Tomislav FRISCIC, Chao-Jun LI, Simon GIRARD, Cristina MOTTILLO, Christopher Walter NICKELS