Abstract: A method can include accessing a depogrid generated via gridding of a structural model in a depositional space and transforming the gridded structural model to a geological space via an inverse mapping where the structural model represents structural features in a subterranean environment based at least in part on data acquired via at least one sensor; determining local u, v and w axes for a plurality of cells in the depogrid via volumetric centroids and vertices represented by coordinates in a depositional space coordinate system (u, v, w) and by coordinates in a physical coordinate system (x, y, z); defining directional geological grid properties based at least in part on the local u, v and w axes; and simulating physical phenomena of the subterranean environment via a simulator based at least in part on at least a portion of the directional geological grid properties.

Abstract: A method for signal modulation includes: receiving network signals from a plurality of participants; analyzing the received network signals to detect latent signals; processing the network signals based on one or more external event data; processing the network signals to exclude sensitive data in the network signals and the latent signals; and encapsulating pan-network signals based on the processed network signals.

Abstract: A method for event detection includes: obtaining a subpopulation data from a graph structure for performing a graph analysis, wherein the subpopulation data is associated with personality and demographic characteristics of users; obtaining a user profile associated with a target user; inferring psychological traits of the user by performing the graph analysis based on the user profile and the subpopulation data; performing an outcome linkage analysis based on labeled event outcome profiles and the inferred psychological traits to generate personalized knowledge graph data associated with the target user; and profiling, monitoring, or performing an anomaly detection for event data streams based on the personalized knowledge graph data.

Abstract: The disclosure relates to therapeutic compositions comprising isolated bacteria useful in the treatment of ulcerative colitis or Crohn's disease. Related methods and uses are also disclosed.

Abstract: The invention relates to bacterial compositions useful in the treatment of cancer. In particular, the compositions can be used as a co-therapy with an immune checkpoint therapy. The invention also relates to methods for identifying a subject that will respond to therapy with an immune checkpoint inhibitor comprising determining the abundance of bacteria in a biological sample from said subject.

Abstract: The invention relates to bacterial compositions useful in the treatment of cancer. In particular, the compositions can be used as a co-therapy with an immune checkpoint therapy. The invention also relates to methods for identifying a subject that will respond to therapy with an immune checkpoint inhibitor comprising determining the abundance of bacteria in a biological sample from said subject.

Abstract: A biological reaction apparatus for receiving at least one substrate having a sample located in a sample region, and a separate cover, such that a reaction chamber is formed between the cover and substrate over the sample region, wherein the apparatus includes a locating means to locate the substrate; a cover locating means for locating and moving the cover with respect to the substrate; a fluid dispensing means for dispensing fluid into the reaction chamber; and a draining mechanism; wherein the draining mechanism includes wicking means.

Abstract: The invention relates to bacterial compositions useful in the treatment of cancer. In particular, the compositions can be used as a co-therapy with an immune checkpoint therapy. The invention also relates to methods for identifying a subject that will respond to therapy with an immune checkpoint inhibitor comprising determining the abundance of bacteria in a biological sample from said subject.

Abstract: The invention relates to bacterial compositions useful in the treatment of cancer. In particular, the compositions can be used as a co-therapy with an immune checkpoint therapy. The invention also relates to methods for identifying a subject that will respond to therapy with an immune checkpoint inhibitor comprising determining the abundance of bacteria in a biological sample from said subject.

Abstract: A biological reaction apparatus for receiving at least one substrate having a sample located in a sample region, and a separate cover, such that a reaction chamber is formed between the cover and substrate over the sample region, wherein the apparatus includes a locating means to locate the substrate; a cover locating means for locating and moving the cover with respect to the substrate; a fluid dispensing means for dispensing fluid into the reaction chamber; and a draining mechanism; wherein the draining mechanism includes wicking means.

Abstract: Methods for modeling and simulating fractured subterranean volumes include a method including obtaining geological data representing a subterranean volume, generating a structural model thereof in depositional space and in structural space. The method includes selecting a first cell and a second cell in the model, the first and second cells being juxtaposed in geological space and defining a fault face where the first and second cells are intersected by a fault, identifying a first point on the fault face, and calculating slip curves. Respective slip curves originate at the point and extend across the fault in geological space to a respective second point of a plurality of second points. The second points are co-located with the first point in the depositional space. The method includes calculating fault rock properties at the first point based on the slip curves and adjusting the model to include the fault rock properties.

Abstract: A system for adapting virtual reality (VR) or augmented reality (AR) content for learning based on a user's interests includes a personalization engine that determines a user's interests and knowledge level regarding a topic, a content modifier that modifies VR or AR content related to the topic according to the users interests and knowledge level, an object selector that selects VR and AR models used to teach the topic during a VR or AR session and modifies the VR and AR models with the modified content based on the user's interests and knowledge level; a VR engine that renders the modified VR and AR models into VR or AR images, and a VR display that displays the VR or AR images. The user's engagement is measured during interaction with the VR display and used to refine and improve an understanding of the user's interest and knowledge level regarding the topic.

Abstract: The Invention relates to bacterial compositions useful in the treatment of cancer. In particular, the compositions can be used as a co-therapy with an immune checkpoint therapy. The invention also relates to methods for identifying a subject that will respond to therapy with an immune checkpoint inhibitor comprising determining the abundance of bacteria in a biological sample from said subject.

Abstract: The invention relates to bacterial compositions useful in the treatment of cancer. In particular, the compositions can be used as a co-therapy with an immune checkpoint therapy. The invention also relates to methods for identifying a subject that will respond to therapy with an immune checkpoint inhibitor comprising determining the abundance of bacteria in a biological sample from said subject.

Abstract: A caching method, system, and computer program product include compiling a combined action of a social interaction with a sharing of an object via a Uniform Resource Locator (URL) in real-time and from an offline database, extracting semantic information from the combined action, describing the semantic information of the combined action as an embedding of the object in a general object vector space, and creating a caching policy for access to the object based on a prediction of an access time derived from the general object vector space and the description of the combined action.

Abstract: A method can include accessing a depogrid generated via gridding of a structural model in a depositional space and transforming the gridded structural model to a geological space via an inverse mapping where the structural model represents structural features in a subterranean environment based at least in part on data acquired via at least one sensor; determining local u, v and w axes for a plurality of cells in the depogrid via volumetric centroids and vertices represented by coordinates in a depositional space coordinate system (u, v, w) and by coordinates in a physical coordinate system (x, y, z); defining directional geological grid properties based at least in part on the local u, v and w axes; and simulating physical phenomena of the subterranean environment via a simulator based at least in part on at least a portion of the directional geological grid properties.

Abstract: According to an embodiment of the present invention, a system dynamically optimizes a service workflow including one or more software services. Initially, the system receives a request to optimize a service workflow, wherein the request includes one or more service requirements and one or more performance objectives related to the one or more service requirements. The system validates service plan information associated with at least one software service plan offered by one or more service providers and generates a plurality of candidate workflows based on the service requirements and performance objectives. The system then determines an optimized workflow from the candidate workflows and executes the optimized workflow to perform operations of the software services. Embodiments of the present invention further include a method and computer program product for dynamically optimizing a service workflow including one or more software services in substantially the same manner as described above.

Abstract: According to an embodiment of the present invention, a system dynamically optimizes a service workflow including one or more software services. Initially, the system receives a request to optimize a service workflow, wherein the request includes one or more service requirements and one or more performance objectives related to the one or more service requirements. The system validates service plan information associated with at least one software service plan offered by one or more service providers and generates a plurality of candidate workflows based on the service requirements and performance objectives. The system then determines an optimized workflow from the candidate workflows and executes the optimized workflow to perform operations of the software services. Embodiments of the present invention further include a method and computer program product for dynamically optimizing a service workflow including one or more software services in substantially the same manner as described above.

Abstract: The present invention provides methods of designing molecularly imprinted polymers (MIPs) which have applications in extracting bioactive compounds from a range of bioprocessing feedstocks and wastes. The present invention is further directed to MIPs designed by the methods of the present invention.

Abstract: A textual content adaption method, system, and computer program product, include receiving a corpus of content, segmenting the content into sections, determining a classification for each section by determining an audience and an expertise level for the section, determining a baseline for a user, modifying a portion of content from the corpus based on the classification of the sections included in the portion of content and based on the baseline of the user, and providing the modified portion of content to the user.