Patents by Inventor Simon Ittig

Simon Ittig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bacteria based protein delivery
    Patent number: 12516089
    Abstract: The present invention relates to recombinant Gram-negative bacterial strains and its use in a method of treating cancer in a subject.
    Type: Grant
    Filed: October 26, 2021
    Date of Patent: January 6, 2026
    Assignee: T3 PHARMACEUTICALS AG
    Inventors: Marlise Amstutz, Simon Ittig, Christoph Kasper, Mathias S. Dick, Falk Saupe
  • Virulence Attenuated Bacteria Based Protein Delivery
    Publication number: 20250368691
    Abstract: The present invention relates to recombinant virulence attenuated Gram-negative bacterial strains and its use in a method of treating cancer in a subject.
    Type: Application
    Filed: June 9, 2025
    Publication date: December 4, 2025
    Inventors: Simon Ittig, Marlise Amstutz, Christoph Kasper
  • Virulence attenuated bacteria based protein delivery
    Patent number: 12358955
    Abstract: The present invention relates to recombinant virulence attenuated Gram-negative bacterial strains and its use in a method of treating cancer in a subject.
    Type: Grant
    Filed: October 18, 2022
    Date of Patent: July 15, 2025
    Assignee: Universitaet Basel
    Inventors: Simon Ittig, Marlise Amstutz, Christoph Kasper
  • Bacteria-Based Protein Delivery
    Publication number: 20240401065
    Abstract: The present invention relates to recombinant Gram-negative bacterial strains and the use thereof for delivery of heterologous proteins into eukaryotic cells.
    Type: Application
    Filed: August 15, 2024
    Publication date: December 5, 2024
    Inventors: Cécile Arrieumerlou, Simon Ittig
  • Bacteria-based protein delivery
    Patent number: 12091670
    Abstract: The present invention relates to recombinant Gram-negative bacterial strains and the use thereof for delivery of heterologous proteins into eukaryotic cells.
    Type: Grant
    Filed: December 3, 2020
    Date of Patent: September 17, 2024
    Assignee: Universitaet Basel
    Inventors: Cécile Arrieumerlou, Simon Ittig
  • Pharmaceutical Combinations for Treating Cancer
    Publication number: 20240165169
    Abstract: The present invention relates to a pharmaceutical combination comprising a recombinant Gram-negative bacterial strain and an immune checkpoint modulator (ICM) and their use in a method for the prevention, delay of progression or treatment of cancer in a subject.
    Type: Application
    Filed: March 24, 2022
    Publication date: May 23, 2024
    Inventors: Simon ITTIG, Christoph KASPER, Falk SAUPE, Marlise AMSTUTZ, Mélodie DUVAL, Irene WAIZENEGGER
  • Pharmaceutical Combinations for Treating Cancer
    Publication number: 20240165265
    Abstract: The present invention relates to a pharmaceutical combination comprising a recombinant Gram-negative bacterial strain and an immune checkpoint modulator (ICM) and their use in a method for the prevention, delay of progression or treatment of cancer in a subject.
    Type: Application
    Filed: March 24, 2022
    Publication date: May 23, 2024
    Inventors: Simon ITTIG, Christoph KASPER, Falk SAUPE, Marlise AMSTUTZ, Mélodie DUVAL
  • BACTERIA BASED PROTEIN DELIVERY
    Publication number: 20230382956
    Abstract: The present invention relates to recombinant Gram-negative bacterial strains and its use in a method of treating cancer in a subject.
    Type: Application
    Filed: October 26, 2021
    Publication date: November 30, 2023
    Inventors: Marlise AMSTUTZ, Simon ITTIG, Christoph KASPER, Mathias S. DICK, Falk SAUPE
  • Virulence Attenuated Bacteria Based Protein Delivery
    Publication number: 20230250138
    Abstract: The present invention relates to recombinant virulence attenuated Gram-negative bacterial strains and its use in a method of treating cancer in a subject.
    Type: Application
    Filed: October 18, 2022
    Publication date: August 10, 2023
    Inventors: Simon Ittig, Marlise Amstutz, Christoph Kasper
  • Bacteria-based protein delivery
    Patent number: 11702663
    Abstract: The present invention relates to recombinant Gram-negative bacterial strains and the use thereof for delivery of repeated domains of a heterologous protein or two or more domains of different heterologous proteins into eukaryotic cells.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: July 18, 2023
    Assignee: Universität Basel
    Inventors: Simon Ittig, Marlise Amstutz, Christoph Kasper
  • Virulence attenuated bacteria based protein delivery
    Patent number: 11518789
    Abstract: The present invention relates to recombinant virulence attenuated Gram-negative bacterial strains and its use in a method of treating cancer in a subject.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: December 6, 2022
    Assignee: Universitaet Basel
    Inventors: Simon Ittig, Marlise Amstutz, Christoph Kasper
  • Virulence attenuated bacteria for treatment of malignant solid tumors
    Patent number: 11166987
    Abstract: The present invention relates to recombinant virulence attenuated Gram-negative bacterial strains for use in a method of treating a malignant solid tumor in a subject.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: November 9, 2021
    Assignee: Universitaet Basel
    Inventors: Simon Ittig, Marlise Amstutz, Christoph Kasper, Guy R. Cornelis
  • Bacteria-Based Protein Delivery
    Publication number: 20210155942
    Abstract: The present invention relates to recombinant Gram-negative bacterial strains and the use thereof for delivery of heterologous proteins into eukaryotic cells.
    Type: Application
    Filed: December 3, 2020
    Publication date: May 27, 2021
    Inventors: Cécile Arrieumerlou, Simon Ittig
  • Bacteria-based protein delivery
    Patent number: 10889823
    Abstract: The present invention relates to recombinant Gram-negative bacterial strains and the use thereof for delivery of heterologous proteins into eukaryotic cells.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: January 12, 2021
    Assignee: Universitaet Basel
    Inventors: Cécile Arrieumerlou, Simon Ittig
  • VIRULENCE ATTENUATED BACTERIA BASED PROTEIN DELIVERY
    Publication number: 20200123207
    Abstract: The present invention relates to recombinant virulence attenuated Gram-negative bacterial strains and its use in a method of treating cancer in a subject.
    Type: Application
    Filed: December 20, 2017
    Publication date: April 23, 2020
    Inventors: Simon Ittig, Marlise Amstutz, Christoph Kasper
  • Bacteria-Based Protein Delivery
    Publication number: 20190194670
    Abstract: The present invention relates to recombinant Gram-negative bacterial strains and the use thereof for delivery of repeated domains of a heterologous protein or two or more domains of different heterologous proteins into eukaryotic cells.
    Type: Application
    Filed: November 17, 2016
    Publication date: June 27, 2019
    Inventors: Simon ITTIG, Marlise AMSTUTZ, Christoph KASPER
  • Virulence Attenuated Bacteria For Treatment Of Malignant Solid Tumors
    Publication number: 20190015497
    Abstract: The present invention relates to recombinant virulence attenuated Gram-negative bacterial strains for use in a method of treating a malignant solid tumor in a subject.
    Type: Application
    Filed: November 17, 2016
    Publication date: January 17, 2019
    Inventors: Simon Ittig, Marlise Amstutz, Christoph Kasper, Guy R. Cornelis
  • Bacteria-Based Protein Delivery
    Publication number: 20170198297
    Abstract: The present invention relates to recombinant Gram-negative bacterial strains and the use thereof for delivery of heterologous proteins into eukaryotic cells.
    Type: Application
    Filed: May 20, 2015
    Publication date: July 13, 2017
    Inventors: Cécile Arrieumerlou, Simon Ittig