Patents by Inventor Simon J. F. Macdonald

Simon J. F. Macdonald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dimeric compounds and their use as anti-viral agents
    Patent number: 7795301
    Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; and n is an integer from 10 to 18 or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.
    Type: Grant
    Filed: May 21, 2007
    Date of Patent: September 14, 2010
    Assignee: Biota Scientific Management Pty, Ltd.
    Inventors: Derek A. Demaine, Graham G. A. Inglis, Simon J. F. MacDonald, Stephen E. Shanahan, Simon P. Tucker, Keith G. Watson, Wen-Yang Wu
  • Dimeric compounds and their use as anti-viral agents
    Patent number: 7504434
    Abstract: The invention relates to compounds of general formula (I), in which: R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; n and q are either the same or different and selected from 0, 1 or 2; and X is an optionally substituted phenyl, optionally substituted naphthyl or optionally substituted phenyl-Y-optionally substituted phenyl in which Y is selected from a covalent bond, CH2, CH2CH2, O or SO2, or a pharmaceutically acceptable derivative thereof, with the proviso that when X is phenyl or naphthyl, n and q are both 2 and when X is phenyl-Y-phenyl in which Y is a covalent bond, then n and q are not both 0, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.
    Type: Grant
    Filed: April 2, 2007
    Date of Patent: March 17, 2009
    Assignee: Biota Scientific Management Pty Ltd.
    Inventors: Derek A. Demaine, Haydn T. Jones, Simon J. F. MacDonald, Andrew McM Mason, Stephen E. Shanahan
  • Dimeric compounds and their use as anti-viral agents
    Patent number: 7468388
    Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, NHCO or O; n is an integer from 2 to 6; and Y is C2-C9 alkyl C3-8 cycloalkyl, C1-C4 alkoxyalkyl, an amino acid or dipeptide, or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection.
    Type: Grant
    Filed: April 12, 2007
    Date of Patent: December 23, 2008
    Assignee: Biota Scientific Management Pty Ltd.
    Inventors: Betty Jin, Simon J. F. MacDonald, Darryl McConnell, Van T. T. Nguyen, Stephen E. Shanahan, Wen-Yang Wu
  • Dimeric compounds and their use as anti-viral agents
    Patent number: 7230028
    Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; and n is an integer from 10 to 18 or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: June 12, 2007
    Assignee: Biota Scientific Management Pty Ltd.
    Inventors: Derek A. Demaine, Graham G. A. Inglis, Simon J. F. MacDonald, Stephen E. Shanahan, Simon P. Tucker, Keith G. Watson, Wen-Yang Wu
  • Dimeric compounds and their use as anti-viral agents
    Patent number: 7223790
    Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, NHCO or O; n is an integer from 2 to 6; and Y is C2–C8 alkyl C3-8 cycloalkyl, C1–C4 alkoxyalkyl, an amino acid or dipeptide, or a pharmaceutically acceptable derivative thereof, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: May 29, 2007
    Assignee: Biota Scientific Management Pty Ltd.
    Inventors: Betty Jin, Simon J. F. MacDonald, Darryl McConnell, Van T. T. Nguyen, Stephen E. Shanahan, Wen-Yang Wu
  • Dimeric compounds and their use as anti-viral agents
    Patent number: 7214707
    Abstract: The invention relates to compounds of general formula (I), in which: R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; n and q are either the same or different and selected from 0, 1 or 2; and X is an optionally substituted phenyl, optionally substituted naphthyl or optionally substituted phenyl-Y-optionally substituted phenyl in which Y is selected from a covalent bond, CH2, CH2CH2, O or SO2, or a pharmaceutically acceptable derivative thereof, with the proviso that when X is phenyl or naphthyl, n and q are both 2 and when X is phenyl-Y-phenyl in which Y is a covalent bond, then n and q are not both 0, methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: May 8, 2007
    Assignee: Biota Scientific Management Pty Ltd.
    Inventors: Derek A. Demaine, Haydn T. Jones, Simon J. F. MacDonald, Andrew McM Mason, Stephen E. Shanahan
  • Dimeric compounds and their use as anti-viral agents
    Patent number: 7157494
    Abstract: The invention relates to compounds of general formula (I); in which R is an amino or guanidino group; R2 is acetyl or trifluoroacetyl; X is CONH, SO2NH, NHCO or NHCONH; m is either 0 or 1; n is an integer from 2 to 6; q is an integer from 0 to 3; and Y is hydrogen or an aromatic substituent, or a pharmaceutically acceptable derivative thereof; methods for their preparation, pharmaceutical formulations containing them or their use in the prevention or treatment of a viral infection
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: January 2, 2007
    Assignee: Biota Scientific Management Pty. Ltd.
    Inventors: Michael D. Dowle, Betty Jin, Simon J. F. Macdonald, Andrew McM Mason, Darryl McConnell, Van T. T. Nguyen, Stephen E. Shanahan, Wen-Yang Wu