Abstract: Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as a pesticides, especially as fungicides.

Abstract: A reusable shipper container has a container body with a payload chamber for holding goods and a lid operable to access the payload chamber. The reusable shipper container also has one or more sensors in the payload chamber to senses a humidity or temperature of the payload chamber or the goods. The reusable shipper container also has a tablet display screen detachably coupled to the container body that wirelessly communicates with the sensors in the payload chamber and that displays one or more of an electronic shipping label, packing instructions, return instructions and maintenance status.

Abstract: The present invention relates to compounds that are Nrf2 activators. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with Nrf2 activation.

Abstract: A breathing assistance apparatus user interface is described which presents animated information related to the management of the apparatus. The user interface is provided on a display screen of the apparatus. The animated illustrations can correspond to operational modes, warnings, user instructions, fault conditions, status, menu options, and the like. The animations can include a sequence of images shown in rapid succession which depict moving icons or objects, scrolling text, flashing colors, or any combination of these or the like. The user interface can combine static information along with animations.

Abstract: The present invention provides a breathing assistance apparatus that has a convenient and effective method of cleaning internal conduits inside the apparatus. The breathing assistance apparatus is preferably a gases supply and humidification device. The cleaning method is a method of disinfection that is automated so minimal training is required to disinfect in particular an internal elbow conduit within the device. It is therefore not necessary to dismantle the gases supply and humidification device, therefore, inadvertent damage to the internal parts of the device is avoided. The present invention also provides a method of disinfecting a heated breathing conduit and a patient interface.

Abstract: One variation of a method for automatically generating a common measurement across multiple assembly units includes: displaying a first image—recorded at an optical inspection station—within a user interface; receiving manual selection of a particular feature in a first assembly unit represented in the first image; receiving selection of a measurement type for the particular feature; extracting a first real dimension of the particular feature in the first assembly unit from the first image according to the measurement type; for each image in a set of images, identifying a feature—analogous to the particular feature—in an assembly unit represented in the image and extracting a real dimension of the feature in the assembly unit from the image according to the measurement type; and aggregating the first real dimension and a set of real dimensions extracted from the set of images into a digital container.

Abstract: Aspects of the disclosure include systems and methods for leveraging a thermally triggered adhesive release for battery service. An exemplary method can include receiving a battery pack having an adhesive layer at an interface between a cooling plate and a component. A heating fluid is directed through an enclosed volume of the cooling plate and a temperature of the adhesive layer is measured. Responsive to determining that the temperature has reached a target temperature, a load is applied to the component until the component is removed.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for transaction management. One of the methods includes, for a first transaction from a plurality of transactions, in response to determining that the first transaction for a corresponding user account at a first entity satisfies the threshold criteria for a corresponding second entity, accessing account data for the corresponding user account, first data for the first entity, and second data for the second entity to complete the first transaction. For a second transaction, in response to determining that the second transaction for a corresponding user account at the first entity does not satisfy the threshold criteria for the corresponding second entity, a determination is made to not access second data for the corresponding second entity, and account data is accessed for the corresponding user account and the first data for the first entity to complete the second transaction.

Abstract: Recombinant monoclonal antibodies (mAbs) and fragments that bind specifically to an HLA-E-peptide complex, including HLA-E-VL9 complexes, and regulate the cytotoxicity effector cell function of NK and/or CD8+ T-cells positive for cell-surface expression of NKG2A (“NKG2A+”). Herein, monoclonal antibodies were recombinantly derived from isolated functional HLA-E-VL9-specific mAbs from HLA-E-VL9 peptide-immunized HLA-B transgenic mice and from the naive human B cell repertoire. Such antibodies are capable of regulating effector cell cytotoxicity and can preferentially recognize HLA-E-VL9 peptide complexes expressed on the surface of tumor cells. The invention provides methods for using HLA-E-VL9 m Abs to modulate NK and/or CD8+ T-cell function as part of immunotherapeutic strategies.

Abstract: Described herein is a data carrier storing program code for causing one or more processors of a data processing system to perform the following steps, the processor(s) having access to multiple criteria, each criterion being associated with an event having a reporting priority: establish a software entity at the data processing system configured to act as a local monitoring entity for the data processing system; monitor the data processing system using the local monitoring entity; raise an event based on the monitoring of the data processing system in dependence on one or more criteria; and in dependence on the event having been raised, assign a heightened reporting priority to one or more other events, the one or more other events being raised in dependence on one or more other criteria.

Abstract: A method for three-dimensional memory stacking may include providing a logic die including a circuit and a memory, providing a memory die including an additional memory having a same footprint as the circuit and memory in the logic die, and stacking the logic die and the memory die three-dimensionally with die-to-die data communication between the circuit and the additional memory by face-to-face hybrid bonds. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: Systems, methods, and computer-readable media are provided for providing pose estimation in extended reality systems. An example method can include tracking, in a lower-power processing mode using a set of lower-power circuit elements on an integrated circuit, a position and orientation of a computing device during a lower-power processing period, the set of lower-power circuit elements including a static random-access memory (SRAM); suspending, based on a triggering event, the tracking in the lower-power processing mode; initiating a higher-power processing mode for tracking the position and orientation of the computing device during a higher-power processing period; and tracking, in the higher-power processing mode using a set of higher-power circuit elements on the integrated circuit and a dynamic random-access memory (DRAM), the position and orientation of the computing device during the higher-power processing period.

Abstract: A system includes a plurality of modular subassemblies and a plate; wherein each modular subassembly comprises an enclosure and a plurality of optical components aligned to the enclosure, and each enclosure comprises a plurality of mounting structures; and wherein each modular subassembly is mechanically coupled to the plate by attachment of a mounting structure of the modular subassembly directly to a corresponding mounting structure located on the plate, such that by mechanically coupling each modular subassembly to the plate using the mounting structure of the modular subassembly and the corresponding mounting structure on the plate, adjacent modular subassemblies are aligned to each other upon such attachment, and wherein two of the modular subassemblies mechanically coupled to the plate are also attached to each other by mechanically coupling an alignment structure on one of the two modular subassemblies to a respective alignment structure on the other of the two modular subassemblies.

Abstract: This disclosure describes techniques that include assessing trust in a system, and in particular, assessing trust by performing a sentiment analysis for an entity or device within a system. In one example, this disclosure describes a method that includes performing, by a computing system and based on information collected about a network entity in a computer network, a sentiment analysis associated with the network entity; determining, by the computing system and based on the sentiment analysis, a trust score for the network entity; and modifying, by the computing system and based on the trust score for the network entity, network operations within the computer network.

Abstract: A plurality of heat exchanger designs with integrated headers are provided. The heat exchanger comprises a heat exchanger matrix with a plurality of flow paths in a first direction wherein the plurality of flow paths are patterned to create a plurality of inputs to the plurality of flow paths on an input surface. The integrated header comprises a primary distribution header and a plurality of distribution header channels that connect to a plurality of feeder tubes that fluidly couple the plurality of distribution header channels with the plurality of matrix inputs such that there is a single feeder tube for each input.

Abstract: Disclosed is a process for the preparation of certain intermediates, e.g. a process for preparing a compound of formula (I) wherein, R1, R2 and X1 are as defined in the description, and which intermediate and processes are useful in the preparation of a BTK inhibitor, such as ibrutinib.