Patents by Inventor Simon John Davies

Simon John Davies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11421030
    Abstract: This invention relates generally to antibodies or antigen binding fragments that bind to human B and T lymphocyte attenuator (BTLA) and uses thereof. More specifically, the invention relates to agonistic antibodies that bind human BTLA and modulate its activity, and their use in treating inflammatory, autoimmune and proliferative diseases and disorders.
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: August 23, 2022
    Assignees: MiroBio Limited, Oxford University Innovation Limited
    Inventors: Simon John Davis, Richard John Cornall, Christopher Douglas Paluch
  • Publication number: 20220177589
    Abstract: This invention relates generally to antibodies or antigen binding fragments that bind to human B and T lymphocyte attenuator (BTLA) and uses thereof. More specifically, the invention relates to agonistic antibodies that bind human BTLA and modulate its activity, and their use in treating inflammatory, autoimmune and proliferative diseases and disorders.
    Type: Application
    Filed: December 27, 2021
    Publication date: June 9, 2022
    Inventors: Simon John Davis, Richard John Cornall, Christopher Douglas Paluch
  • Publication number: 20220064300
    Abstract: Provided herein are antibody construct molecules comprising (i) an Fc receptor binding site, (ii) an antigen-binding site and (iii) a spacer moiety located between (i) and (ii), wherein the spacer moiety serves to increase the distance between (i) and (ii) so as to reduce the agonistic activity of the molecule as compared to the antibody variant that lacks (iii). Disclosed are various antibodies that can be de-agonized by introduction of the spacer moiety. Of specific interest are agonistic check point targeting antibodies that are de-agonized by introduction of the spacer moiety.
    Type: Application
    Filed: December 17, 2019
    Publication date: March 3, 2022
    Inventor: Simon John Davis
  • Publication number: 20210277123
    Abstract: This invention relates generally to antibodies or antigen binding fragments that bind to human B and T lymphocyte attenuator (BTLA) and uses thereof. More specifically, the invention relates to agonistic antibodies that bind human BTLA and modulate its activity, and their use in treating inflammatory, autoimmune and proliferative diseases and disorders.
    Type: Application
    Filed: May 25, 2021
    Publication date: September 9, 2021
    Inventors: Simon John Davis, Richard John Cornall, Christopher Douglas Paluch
  • Patent number: 8769808
    Abstract: A method for implementing an electrical system architecture capable of providing fixed or modular components, for example, interface connectors, is provided. Fixed components allow product cost to be minimized. Modular components provide flexible configurability of products. In accordance with at least one embodiment of the present invention, an electrical system architecture capable of providing fixed or modular components minimizes costs such as design, production, and customer support costs while being able to provide a range of product variants.
    Type: Grant
    Filed: October 17, 2005
    Date of Patent: July 8, 2014
    Assignee: Alcatel Lucent
    Inventors: Simon John Davis, Denis Junior King, Dion Pike, Joey M. W. Chow, Mark R. Megarity
  • Patent number: 7679924
    Abstract: A configurable chassis guidance system and method are described. The system may be practiced as a chassis and/or a module or an element thereof (e.g., a mating guide). The system and method allow reconfiguration of multiple modules of various module widths without the need for removal or reinstallation of module guides mounted on the chassis. As an example, a single-width module may be removed and replaced by a double-width module or quadruple-width module without removing module guides used to engage the single-width module. As another example, a double-width module or quadruple-width module may be removed and replaced by a single-width module without removing module guides used to engage the double-width module or quadruple-width module. The system and method may be practiced so as not to impair compatibility of modules with card edge module guides that engage an edge of a circuit board of a module.
    Type: Grant
    Filed: May 19, 2006
    Date of Patent: March 16, 2010
    Assignee: Alcatel Lucent
    Inventors: Simon John Davis, Mark R. Megarity, Joey M. W. Chow, Dion Pike
  • Publication number: 20040256118
    Abstract: A nozzle has a body with a central cavity from which a plurality of fire extinguishant fluid outlets extend. The outlets extend non-radially with respect to the central axis of the cavity, i.e. at least a portion of each outlet is inclined with respect to any plane parallel to and passing through the central axis of the cavity which intersects the portion of the outlet. The extinguishant from the non-radial outlets is thrown towards the walls of the chamber, along the paths. The jets of the fluid induce a rotational movement within the ambient fluid (for example, air) already present in the chamber, thus creating a vortex or rotational movement of the fluid within the chamber. In another embodiment, the vortex or rotational movement is generated by a nozzle assembly of generally cruciform configuration with three or more discharge tubes having outlets formed therein for discharging extinguishant in equi-angularly-spaced directions.
    Type: Application
    Filed: April 8, 2004
    Publication date: December 23, 2004
    Applicants: KIDDE-FENWAL INC., KIDDE IP HOLDINGS LIMITED
    Inventors: Robert George Dunster, Simon John Davies, Robert James Lade, Kurt D. Lovell
  • Publication number: 20040163825
    Abstract: A fire and explosion suppression system comprises a source (5) of high pressure water which is fed to a misting nozzle (13) or other water mist generating means at one input of a mixing unit (6), and a source (14) of high pressure inert gas, such as nitrogen, which is fed along a pipe (20) to another input of the mixing unit (6). Inside the mixing unit (6), water mist, in the form of an atomised mist of very small droplet size is mixed with the pressurised gas and exits the mixing unit (6) at high pressure and high velocity along a pipe (22) and is thence discharged through spreaders (26, 28). Separation of the mist production from the actual discharge of the mist, and the entraining and transporting of the mist between these two stages at high pressure and high velocity, produces an output mist of very small droplet size which is carried by the entraining and transporting high pressure gas into the area to be protected, enabling a total flooding capability.
    Type: Application
    Filed: March 29, 2004
    Publication date: August 26, 2004
    Inventors: Robert George Dunster, Simon John Davies, Robert James Lade, Julian Grigg
  • Publication number: 20020168417
    Abstract: Agrochemical compositions including compounds of the general formula (I), as defined herein, such as, N-(1-deoxy glucityl)N-(2 hydroxy dodecyl)-N-methyl amine, can function as emulsifiers, dispersants or, and particularly, as adjuvants. The agrochemical can be a plant growth regulators, herbicides, and/or pesticides, for example insecticides, fungicides, acaricides, nematocides, miticides, rodenticides, bactericides, molluscicides and/or a bird repellent. Particularly useful formulations include water soluble herbicide(s), particularly such as Glyphosate, Sulfosate, Glufosinate and Paraquat.
    Type: Application
    Filed: January 16, 2002
    Publication date: November 14, 2002
    Inventors: Trevor Graham Blease, Hanamanthsa Shankarsa Bevinakatti, Steven Irene Jozef Reekmans, Edward George Scovell, Simon John Davies
  • Patent number: D566275
    Type: Grant
    Filed: May 18, 2006
    Date of Patent: April 8, 2008
    Assignee: Enztec Limited
    Inventors: Paul John Morrison, Simon John Davis