Patents by Inventor Simon Karpatkin

Simon Karpatkin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic agents for inducing platelet fragmentation and treating thromboembolic disorders
    Patent number: 8753631
    Abstract: The present invention is directed to a therapeutic agent comprising a GPIIIa(49-66) specific targeting agent and a thrombi-specific homing agent. Also disclosed is the use of the therapeutic agent in carrying out a method of treating thromboembolic disorders and a method of inducing platelet fragmentation.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: June 17, 2014
    Assignee: New York University
    Inventors: Simon Karpatkin, Michael Nardi, Zongdong Li
  • AGENTS THAT DISSOLVE ARTERIAL THROMBI
    Publication number: 20110052594
    Abstract: Agents that induce platelet fragmentation include an IgG antibody that reacts with platelet epitope GPIIIA49-66 on platelet membrane, recombinant AMANTS-18, phorbol 12-myristate 13-acetate (PMA) and A23817.
    Type: Application
    Filed: February 11, 2009
    Publication date: March 3, 2011
    Applicant: NEW YORK UNIVERSITY
    Inventors: Simon Karpatkin, Michael Nardi
  • THERAPEUTIC AGENTS FOR INDUCING PLATELET FRAGMENTATION AND TREATING THROMBOEMBOLIC DISORDERS
    Publication number: 20110045008
    Abstract: The present invention is directed to a therapeutic agent comprising a GPIIIa(49-66) specific targeting agent and a thrombi-specific homing agent. Also disclosed is the use of the therapeutic agent in carrying out a method of treating thromboembolic disorders and a method of inducing platelet fragmentation.
    Type: Application
    Filed: April 30, 2010
    Publication date: February 24, 2011
    Applicant: NEW YORK UNIVERSITY
    Inventors: Simon Karpatkin, Magaret Karpatkin, Michael Nardi, Zongdong Li
  • Agents that dissolve arterial thrombi
    Publication number: 20070009529
    Abstract: Agents that induce platelet fragmentation include an IgG antibody that reacts with platelet epitope GPIIIA49-66 on platelet membrane, recombinant AMANTS-18, phorbol 12-myristate 13-acetate (PMA) and A23817.
    Type: Application
    Filed: June 22, 2006
    Publication date: January 11, 2007
    Applicant: New York University
    Inventors: Simon Karpatkin, Michael Nardi
  • Methods and compositions for the growth and maintenance of stem cells
    Publication number: 20060134784
    Abstract: The present invention relates to pluripotent stem cells and methods of promoting long term growth of such cells. In particular, the methods described are used to enhance the proliferation of hematopoietic stem cells, hematopoietic precursor cells, hemangioblasts and endothelial stem cells. The present invention also relates to methods of using such cells, comprising introducing such stem cells, into the host. The present invention also relates to pharmaceutical compositions comprising the cells and such compositions may include growth factors or cytokines to allow for further cell growth and/or cellular differentiation. The invention further relates to methods of in vivo administration of a protein or gene of interest comprising transfecting the stem cells grown by the methods described, with a construct comprising DNA which encodes a protein of interest and then introducing the stem cell into the host where the protein or gene of interest is expressed.
    Type: Application
    Filed: November 30, 2005
    Publication date: June 22, 2006
    Inventors: Ross Basch, Simon Karpatkin, Rashmi Gupta
  • Antibodies that dissolve arterial thrombi
    Publication number: 20040236079
    Abstract: An IgG antibody which induces platelet fragmentation. The antibody reacts with platelet epitope GPIIIa49-66 on platelet membranes. This antibody, or a monoclonal antibody derived from the GPIIIa49-66 epitope, will dissolve arterial thrombi generally found in the coronary arteries of patients with acute myocardial infarction as well as other arterial occlusions.
    Type: Application
    Filed: July 20, 2004
    Publication date: November 25, 2004
    Inventors: Simon Karpatkin, Michael Nardi