Abstract: A magnetic resonance (MR) compatible transducer for magnetic resonance elastography applications has a cantilevered drive element a free end of which is arranged in use to move reciprocally, and a flexible non-conductive connection rod slidably disposed within a flexible non-conductive sleeve. The connection rod is affixed at a proximal end to the cantilevered drive element via a proximal flexible connection piece that in use accommodates the slight rotational movement of the cantilevered drive element as it reciprocates about its secured end, whilst translating the rotational reciprocation of the cantilevered drive element into a pure translational reciprocation of the connection rod within the sleeve. The distal end of the connection rod is affixed against a protrusion connected to another cantilevered driven element, upon which is mounted a piston element that in use contacts the subject.

Abstract: A level measurement instrument including: a transmitter configured to transmit an electromagnetic transmission signal, the electromagnetic transmission signal being a microwave signal or a radio wave signal a receiver configured to receive a plurality of electromagnetic return signals; an elongate electromagnetic radiation guide coupled to the transmitter to guide the electromagnetic transmission signal, wherein the elongate electromagnetic radiation guide is provided with a plurality of windows spaced along the elongate electromagnetic radiation guide, the windows being at least partially transmissive to the electromagnetic transmission signal such that in use, when the elongate electromagnetic radiation guide is introduced into a fluid column, the electromagnetic transmission signal interacts with fluid adjacent each window and generates electromagnetic return signals, the return signal from each window being dependent on a parameter of the fluid adjacent each window such that different fluids in the fluid

Abstract: In the field of obesity related disease, identification of patients with nonalcoholic steatohepatitis (NASH) would be useful to counsel them more intensively on diet and lifestyle changes and propose new pharmacological treatments. As a consequence, the inventors worked on a method for post-processing images of a region of interest of the liver for reconstructing a map of the internal magnetic susceptibility by using a Bayesian regularization approach to inverse the internal magnetic field. Such method can be implemented on computer and provides better results than other known methods for obesity related disease. This method may be applied for predicting that a subject is at risk of suffering from such disease, diagnosing a disease, identifying a therapeutic or a biomarker and screening compounds useful as a medicine.

Abstract: A medial plate for treating fractures along a clavicle, comprising a plate body including a longitudinal component extending from a first end to a second end and an extension extending from the second end, the second end configured to be mounted over a medial head, a first set of variable angle holes extending through a portion of the longitudinal component including the second end of the longitudinal component and the extension, each of the first set of variable angle holes extending through the plate body along a central axis so that a bone screw is insertable therethrough at a user-selected angle relative to the central axis, and a plurality of combination holes extending through the longitudinal component, each of the plurality of combination holes includes a first portion configured to receive a bone screw at a user-selected angle and a second portion configured to receive a compression screw.

Abstract: A medial plate for treating fractures along a clavicle, comprising a plate body including a longitudinal component extending from a first end to a second end and an extension extending from the second end, the second end configured to be mounted over a medial head, a first set of variable angle holes extending through a portion of the longitudinal component including the second end of the longitudinal component and the extension, each of the first set of variable angle holes extending through the plate body along a central axis so that a bone screw is insertable therethrough at a user-selected angle relative to the central axis, and a plurality of combination holes extending through the longitudinal component, each of the plurality of combination holes includes a first portion configured to receive a bone screw at a user-selected angle and a second portion configured to receive a compression screw.

Abstract: In the field of obesity related disease, identification of patients with nonalcoholic steatohepatitis (NASH) would be useful to counsel them more intensively on diet and lifestyle changes and propose new pharmacological treatments. As a consequence, the inventors worked on a method for post-processing images of a region of interest of the liver for reconstructing a map of the internal magnetic susceptibility by using a Bayesian regularization approach to inverse the internal magnetic field. Such method can be implemented on computer and provides better results than other known methods for obesity related disease. This method may be applied for predicting that a subject is at risk of suffering from such disease, diagnosing a disease, identifying a therapeutic or a biomarker and screening compounds useful as a medicine.

Abstract: A medial plate for treating fractures along a clavicle, comprising a plate body including a longitudinal component extending from a first end to a second end and an extension extending from the second end, the second end configured to be mounted over a medial head, a first set of variable angle holes extending through a portion of the longitudinal component including the second end of the longitudinal component and the extension, each of the first set of variable angle holes extending through the plate body along a central axis so that a bone screw is insertable therethrough at a user-selected angle relative to the central axis, and a plurality of combination holes extending through the longitudinal component, each of the plurality of combination holes includes a first portion configured to receive a bone screw at a user-selected angle and a second portion configured to receive a compression screw.

Abstract: It is proposed a method for post-processing images of an region of interest in a subject, the images being acquired with a magnetic resonance imaging technique, the method for post-processing comprising at least the step of: —unwrapping the phase of each image, —extracting a complex signal over echo time for at least one pixel of the unwrapped images, and —calculating fat characterization parameters by using a fitting technique applied on a model, the model being a function which associates to a plurality of parameters each extracted complex signal, the plurality of parameters comprising at least two fat characterization parameters, the magnitude error and the phase error generated by the use of the bipolar readout gradients, the fitting technique being a non-linear least-square fitting technique using pseudo-random initial conditions.

Abstract: A method for post-processing images of a region of interest in a subject, the images being acquired with a magnetic resonance imaging technique, the method for post-processing comprising at least the step of: unwrapping the phase of each image, extracting a real signal over echo time for at least one pixel of the unwrapped images, and calculating fat characterization parameters by using a fitting technique applied on a model, the model being a function which associates to a plurality of parameters each extracted real signal, the plurality of parameters comprising at least two fat characterization parameters and at least one parameter obtained by a measurement, the fitting technique being a non-linear least-square fitting technique using pseudo-random initial conditions.

Abstract: Embodiments of the invention provide a magnetic resonance (MR) compatible transducer for magnetic resonance elastography applications having a cantilevered drive element (54) a free end of which is arranged in use to move reciprocally, and a flexible non-conductive connection rod (62) slidably disposed within a flexible non-conductive sleeve (60). The connection rod is affixed at a proximal end to the cantilevered drive element via a proximal flexible connection piece (64) that in use accommodates the slight rotational movement of the cantilevered drive element as it reciprocates about its secured end, whilst translating the rotational reciprocation of the cantilevered drive element into a pure translational reciprocation of the connection rod within the sleeve. The distal end of the connection rod is affixed against a protrusion connected to another cantilevered driven element (56), upon which is mounted a piston element (58) that in use contacts the subject.

Abstract: A method for post-processing images of a region of interest in a subject, the images being acquired with a magnetic resonance imaging technique, the method for post-processing comprising at least the step of: unwrapping the phase of each image, extracting a real signal over echo time for at least one pixel of the unwrapped images, and calculating fat characterization parameters by using a fitting technique applied on a model, the model being a function which associates to a plurality of parameters each extracted real signal, the plurality of parameters comprising at least two fat characterization parameters and at least one parameter obtained by a measurement, the fitting technique being a non-linear least-square fitting technique using pseudo-random initial conditions.

Abstract: It is proposed a method for post-processing images of an region of interest in a subject, the images being acquired with a magnetic resonance imaging technique, the method for post-processing comprising at least the step of:—unwrapping the phase of each image,—extracting a complex signal over echo time for at least one pixel of the unwrapped images, and—calculating fat characterization parameters by using a fitting technique applied on a model, the model being a function which associates to a plurality of parameters each extracted complex signal, the plurality of parameters comprising at least two fat characterization parameters, the magnitude error and the phase error generated by the use of the bipolar readout gradients, the fitting technique being a non-linear least-square fitting technique using pseudo-random initial conditions.

Abstract: A detector probe for detecting ionizing radiation includes at least one detector (14) mounted on a support (12), and an electrically operated source of heat (18) arranged on the support in proximity to the detector so that the temperature of the detector may be changed by operation of the heat source. The detector probe may be used in the manufacture of a level gauge or density profiler.

Abstract: A method for post-processing images of a region of interest in a subject, the images being acquired with a magnetic resonance imaging technique, the method for post-processing comprising at least the step of: unwrapping the phase of each image, extracting a real signal over echo time for at least one pixel of the unwrapped images, and calculating fat characterization parameters by using a fitting technique applied on a model, the model being a function which associates to a plurality of parameters each extracted real signal, the plurality of parameters comprising at least two fat characterization parameters and at least one parameter obtained by a measurement, the fitting technique being a non-linear least-square fitting technique using pseudo-random initial conditions.

Abstract: A detector probe for detecting ionising radiation includes at least one detector (14) mounted on a support (12), and an electrically operated source of heat (18) arranged on the support in proximity to the detector so that the temperature of the detector may be changed by operation of the heat source. The detector probe may be used in the manufacture of a level gauge or density profiler.

Abstract: In a first aspect the present invention provides a glenoid prosthesis assembly for use in shoulder joint arthroplasty to address conditions where deterioration of the rotator cuff mechanism of the shoulder joint is severe, the assembly comprising a first shell component to be affixed to a scapula by fixing means, and a smaller second component adapted to nest within the first component and having an articulation surface for articulating with a humeral head, the first component being over-sized relative to the glenoid surface of a scapula whereby the first component may be first affixed to at least two of the glenoid, acromion and coracoid processes of the scapula in use by the fixing means and the second component may be cemented in place within the first component allowing initial adjustability in the poise of the second component relative to the first component.