Patents by Inventor Simon Lopez

Simon Lopez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070072170
    Abstract: Methods for determining the responsiveness of a patient to recombinant human erythropoietin therapy are disclosed. In one approach, the method includes obtaining a volume-Hgb factor (VHf) defined as a product function of MCV and Hgb from a patient's blood sample; comparing VHf to a predetermined criterion; and reporting indication of responder if VHf meets the predetermined criterion. The method further includes using a RBC size-hemoglobin factor (RSHf) defined as a product function of MCV, MRV and Hgb, or using a function of VHf and RDW for determining the responsiveness. In another approach, the method includes using a RBC size factor (RSf) defined as a product function of MCV and MRV, in combination with transferrin saturation (TSAT) for determining the responsiveness to the erythropoietin therapy.
    Type: Application
    Filed: September 21, 2006
    Publication date: March 29, 2007
    Applicant: Beckman Coulter, Inc.
    Inventor: Ramon Simon-Lopez
  • Publication number: 20050221396
    Abstract: A method of detecting parasite infection, particularly malaria, includes mixing a blood sample with a lytic reagent system to lyse red blood cells, and to form a sample mixture; performing a differential analysis of white blood cells of the sample mixture on a blood analyzer, and obtaining a cell volume distribution of a white blood cell subpopulation from a cell volume measurement used in the differential analysis; obtaining a cell volume parameter from the cell volume distribution of the white blood cell subpopulation; evaluating the cell volume parameter against a predetermined criterion, and reporting an indication of the parasite infection if the cell volume parameter meets the predetermined criterion. The method also uses a discriminant obtained from cell volume parameters of two different white blood cell subpopulations against a predetermined criterion. The method further use a cell distribution parameter of a cell distribution obtained using a RF impedance measurement.
    Type: Application
    Filed: February 18, 2005
    Publication date: October 6, 2005
    Applicant: Beckman Coulter, Inc.
    Inventor: Ramon Simon-Lopez
  • Publication number: 20040070123
    Abstract: A tundish impact pad formed from refractory material, the impact pad (1) comprising a base (3) having an impact surface (5) which in use faces upwardly to receive molten metal poured onto the impact pad, and a wall (7) extending upwardly from the base around at least part of the periphery of the impact surface, the wall including an overhang (9) projecting over a peripheral region (11) of the impact surface (5), the overhang (9) including a plurality of protrusions (13) which project further over the impact surface (5) than the remainder of the overhang (5).
    Type: Application
    Filed: April 10, 2003
    Publication date: April 15, 2004
    Applicant: Foseco International Limited
    Inventors: Rodolfo D. Morales, Jorge Palafox-Ramos, Simon Lopez-Ramirez
  • Publication number: 20020033567
    Abstract: A tundish impact pad formed from refractory material, the impact pad (1) comprising a base (3) having an impact surface (5) which in use faces upwardly to receive molten metal poured onto the impact pad, and a wall (7) extending upwardly from the base around at least part of the periphery of the impact surface, the wall including an overhang (9) projecting over a peripheral region (11) of the impact surface (5), the overhang (9) including a plurality of protrusions (13) which project further over the impact surface (5) than the remainder of the overhang (5).
    Type: Application
    Filed: November 7, 2001
    Publication date: March 21, 2002
    Inventors: Rodolfo Davila Morales, Jorge Palafox-Ramos, Simon Lopez-Ramirez