Abstract: The present disclosure describes compositions containing cyclodextrin and methods of using cyclodextrins to stimulate or enhance the immune system and response in fish. Methods of enhancing the efficacy of a fish vaccine by administering cyclodextrin to the fish are also described.

Abstract: A phosphodiesterase 10A inhibitor serving as an effective prophylactic or therapeutic agent for Parkinson's disease, Huntington's disease, Alzheimer's disease, and schizophrenia. The PDE10A inhibitor contains as an active ingredient a pyrazolo[1,5-a]pyridine derivative represented by the following general formula: wherein R1 and R2 are each independently a hydrogen atom or a lower alkyl group having 1 to 4 carbons; and R3 is a hydrogen atom, a lower alkyl group having 1 to 4 carbons, or a lower alkoxyl group having 1 to 3 carbons.

Abstract: This invention is directed toward a multiple dice device and operational system utilizing one or more inner dice enclosed within a clear, outer die with independent rolling and chance capabilities. Within a clear outer die there is enclosed one or more inner dice which roll independently of the outer die, such that with a roll on the outer die by a user two or more chance results can be obtained. The outer and inner dice can be the standard 1-6 numerical dice, purely directional dice, dice with symbols on them or a combination of the various possible surfaces.

Abstract: The invention relates generally to the methods of treating brain diseases and compounds for treating brain diseases, and more specifically relates to using compounds that are able to modulate guanine nucleotide exchange factors for proteins belonging to the Rap family of small GTPases to treat diseases of the brain, such as Alzheimer's and Schizophrenia.

Abstract: This invention is directed toward a multiple dice device and operational system utilizing one or more inner dice enclosed within a clear, outer die with independent rolling and chance capabilities. Within a clear outer die there is enclosed one or more inner dice which roll independently of the outer die, such that with a roll on the outer die by a user two or more chance results can be obtained. The outer and inner dice can be the standard 1-6 numerical dice, purely directional dice, dice with symbols on them or a combination of the various possible surfaces.

Abstract: A phosphodiesterase 10A inhibitor serving as an effective prophylactic or therapeutic agent for Parkinson's disease, Huntington's disease, Alzheimer's disease, and schizophrenia. The PDE10A inhibitor contains as an active ingredient a pyrazolo[1,5-a]pyridine derivative represented by the following general formula: wherein R1 and R2 are each independently a hydrogen atom or a lower alkyl group having 1 to 4 carbons; and R3 is a hydrogen atom, a lower alkyl group having 1 to 4 carbons, or a lower alkoxyl group having 1 to 3 carbons.