Patents by Inventor Simon McCarthy
Simon McCarthy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12114722Abstract: A hat headliner with temperature control members that is configured to provide a temperature dissimilar to that of its environment at locations along a lower edge of a hat. The present invention includes a body that is either permanently or releasably secured into the head cavity of a hat. The body of the present invention includes a perimeter band member wherein the perimeter band member has formed therein a plurality of receptacles. The plurality of receptacles have an interior volume wherein the interior volume is configured to receive and store temperature members. The temperature members include a housing from a malleable material having a temperature controlling gel therein. The receptacles have a first side and a second side wherein the first side of the receptacle is manufactured from a thermally conductive material and is adjacent a wearer's head.Type: GrantFiled: October 24, 2022Date of Patent: October 15, 2024Inventor: Simon McCarthy
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Publication number: 20240225164Abstract: A hat headliner with temperature control members that is configured to provide a temperature dissimilar to that of its environment at locations along a lower edge of a hat. The present invention includes a body that is either permanently or releasably secured into the head cavity of a hat. The body of the present invention includes a perimeter band member wherein the perimeter band member has formed therein a plurality of receptacles. The plurality of receptacles have an interior volume wherein the interior volume is configured to receive and store temperature members. The temperature members include a housing from a malleable material having a temperature controlling gel therein. The receptacles have a first side and a second side wherein the first side of the receptacle is manufactured from a thermally conductive material and is adjacent a wearer's head.Type: ApplicationFiled: October 24, 2022Publication date: July 11, 2024Inventor: Simon McCarthy
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Publication number: 20240216571Abstract: The present chitosan-based superfine fiber invention relates to compositions, formulations, and processes that result in numerous significant advantages for the production and use of superfine fiber bioactive matrices in biomedical applications. The present invention relates to superfine, chitosan-based fibers, wherein the chitosan-based fibers have a percentage chitosan content of at least about 20% w/w, and highly conformable and compliant matrices comprising such fibers, processes for their production, and related formulations. The superfine chitosan-based fibers of the invention preferably include microfibers with diameter less than or equal to about 10 microns and micron and submicron fibers that are about 2 microns and less.Type: ApplicationFiled: January 17, 2024Publication date: July 4, 2024Inventors: Brian Clare, Radim Dvorák, Simon McCarthy, Jirí Machát
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Publication number: 20240130455Abstract: A hat headliner with temperature control members that is configured to provide a temperature dissimilar to that of its environment at locations along a lower edge of a hat. The present invention includes a body that is either permanently or releasably secured into the head cavity of a hat. The body of the present invention includes a perimeter band member wherein the perimeter band member has formed therein a plurality of receptacles. The plurality of receptacles have an interior volume wherein the interior volume is configured to receive and store temperature members. The temperature members include a housing from a malleable material having a temperature controlling gel therein. The receptacles have a first side and a second side wherein the first side of the receptacle is manufactured from a thermally conductive material and is adjacent a wearer's head.Type: ApplicationFiled: October 23, 2022Publication date: April 25, 2024Inventor: Simon McCarthy
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Patent number: 11890384Abstract: The present chitosan-based superfine fiber invention relates to compositions, formulations, and processes that result in numerous significant advantages for the production and use of superfine fiber bioactive matrices in biomedical applications. The present invention relates to superfine, chitosan-based fibers, wherein the chitosan-based fibers have a percentage chitosan content of at least about 20% w/w, and highly conformable and compliant matrices comprising such fibers, processes for their production, and related formulations. The superfine chitosan-based fibers of the invention preferably include microfibers with diameter less than or equal to about 10 microns and micron and submicron fibers that are about 2 microns and less.Type: GrantFiled: February 13, 2017Date of Patent: February 6, 2024Assignee: Tricol Biomedical, Inc.Inventors: Brian Clare, Radim Dvo{hacek over (r)}ák, Simon McCarthy, Jiri Machát
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Patent number: 11234998Abstract: The present invention comprises chitosan materials and methods of using carbonic acid for aqueous solubilization of neutralized or pre-treated chitosan gels and provides, among other things, substantially acid salt free composition native final forms without requiring subsequent acid salt elution. The invention includes chitosan-based solid and semi-solid material forms, optionally reinforced with chitosan fibers, such as powders, fibers, films, matrices, sponges, implants, scaffolds, fillers, and hydrogels. Native final forms are produced from chitosan powder solubilized in an aqueous acidic solution, processed to form a high pH hydrated chitosan gel precipitate material that is then neutralized by water washing and re-solubilized substantially to chitosan solution using carbonic acid.Type: GrantFiled: March 17, 2020Date of Patent: February 1, 2022Assignee: Tricol Biomedical, Inc.Inventors: Simon McCarthy, Barbara McGrath, Sam Kuhn, Jess Kimball, Michael Stolten, Amanda Bennett
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Patent number: 11229724Abstract: The invention relates to biocompatible, bioabsorbable derivatized non-crosslinked chitosan compositions optionally crosslinked to gelatin/collagen by 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride (EDC) for biomedical use and methods of making and testing such compositions, including a modified acute systemic toxicity test. The compositions comprise derivatized chitosan reacetylated to a degree of N-deacetylation (DDA) of between about 15% and 40%. The compositions are typically bioabsorbed in about 90 days or less and can be made to bioabsorb at differing rates of speed. The compositions are initially soluble in aqueous solution below pH 6.5. The compositions have an acid content that can be adjusted between about 0% (w/w) and about 8% (w/w) to customize the composition for uses that require and/or tolerate differing levels of cytotoxicity, adhesion, composition cohesion, and cell infiltration into the composition.Type: GrantFiled: June 4, 2020Date of Patent: January 25, 2022Assignee: Tricol Biomedical, Inc.Inventors: Barbara McGrath, Simon McCarthy, Sam Kuhn, Alysha Wold, Michael Stolten, Amanda Bennett
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Patent number: 11160901Abstract: An aqueous chitosan gel system of novel non-scarring, non-interfering, transparent, stable, solubilized chitosan that controls bleeding is described herein. The aqueous chitosan gel system can comprise water, chitosan, an acid, a plasticizer, a rheology modifying agent, an antioxidant stabilizer, an alcohol, and a multi-valent salt. Additional components of the aqueous chitosan gel system can comprise a bifunctional organic acid, a tnfunctional organic acid, a multi-functional organic acid, a phosphoric acid, a polyphosphoric acid and a salt.Type: GrantFiled: April 11, 2016Date of Patent: November 2, 2021Assignee: TRICOL BIOMEDICAL, INC.Inventors: Maggie Bush, Sam Kuhn, Simon McCarthy
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Publication number: 20200397950Abstract: The invention relates to biocompatible, bioabsorbable derivatized non-crosslinked chitosan compositions optionally crosslinked to gelatin/collagen by 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride (EDC) for biomedical use and methods of making and testing such compositions, including a modified acute systemic toxicity test. The compositions comprise derivatized chitosan reacetylated to a degree of N-deacetylation (DDA) of between about 15% and 40%. The compositions are typically bioabsorbed in about 90 days or less and can be made to bioabsorb at differing rates of speed. The compositions are initially soluble in aqueous solution below pH 6.5. The compositions have an acid content that can be adjusted between about 0% (w/w) and about 8% (w/w) to customize the composition for uses that require and/or tolerate differing levels of cytotoxicity, adhesion, composition cohesion, and cell infiltration into the composition.Type: ApplicationFiled: June 4, 2020Publication date: December 24, 2020Inventors: Barbara McGrath, Simon McCarthy, Sam Kuhn, Alysha Wold, Michael Stolten, Amanda Bennett
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Publication number: 20200360419Abstract: The present invention comprises chitosan materials and methods of using carbonic acid for aqueous solubilization of neutralized or pre-treated chitosan gels and provides, among other things, substantially acid salt free composition native final forms without requiring subsequent acid salt elution. The invention includes chitosan-based solid and semi-solid material forms, optionally reinforced with chitosan fibers, such as powders, fibers, films, matrices, sponges, implants, scaffolds, fillers, and hydrogels. Native final forms are produced from chitosan powder solubilized in an aqueous acidic solution, processed to form a high pH hydrated chitosan gel precipitate material that is then neutralized by water washing and re-solubilized substantially to chitosan solution using carbonic acid.Type: ApplicationFiled: March 17, 2020Publication date: November 19, 2020Inventors: Simon McCarthy, Barbara McGrath, Sam Kuhn, Jess Kimball, Michael Stolten, Amanda Bennett
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Patent number: 10709817Abstract: The invention relates to biocompatible, bioabsorbable derivatized non-crosslinked chitosan compositions optionally crosslinked to gelatin/collagen by 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride (EDC) for biomedical use and methods of making and testing such compositions, including a modified acute systemic toxicity test. The compositions comprise derivatized chitosan reacetylated to a degree of N-deacetylation (DDA) of between about 15% and 40%. The compositions are typically bioabsorbed in about 90 days or less and can be made to bioabsorb at differing rates of speed. The compositions are initially soluble in aqueous solution below pH 6.5. The compositions have an acid content that can be adjusted between about 0% (w/w) and about 8% (w/w) to customize the composition for uses that require and/or tolerate differing levels of cytotoxicity, adhesion, composition cohesion, and cell infiltration into the composition.Type: GrantFiled: February 13, 2018Date of Patent: July 14, 2020Assignee: Tricol Biomedical, Inc.Inventors: Barbara McGrath, Simon McCarthy, Sam Kuhn, Alysha Wold, Michael Stolten, Amanda Bennett
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Patent number: 10632143Abstract: The present invention comprises chitosan materials and methods of using carbonic acid for aqueous solubilization of neutralized or pre-treated chitosan gels and provides, among other things, substantially acid salt free composition native final forms without requiring subsequent acid salt elution. The invention includes chitosan-based solid and semi-solid material forms, optionally reinforced with chitosan fibers, such as powders, fibers, films, matrices, sponges, implants, scaffolds, fillers, and hydrogels. Native final forms are produced from chitosan powder solubilized in an aqueous acidic solution, processed to form a high pH hydrated chitosan gel precipitate material that is then neutralized by water washing and re-solubilized substantially to chitosan solution using carbonic acid.Type: GrantFiled: February 13, 2018Date of Patent: April 28, 2020Assignee: Tricol Biomedical, Inc.Inventors: Simon McCarthy, Barbara McGrath, Sam Kuhn, Jess Kimball, Michael Stolten, Amanda Bennett
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Publication number: 20180263634Abstract: The present invention relates to a compressive band and hemostatic dressing system and related methods of use to provide rapid, non-occlusive bleeding control, arterial injury treatment, and injury protection comfortably and reliably after vascular access procedures. The present invention may comprise some or all of the following elements: a positioner assembly, a compressive cushion component, a compression plate, a strap with a flexible hinge assembly, and a hemostatic dressing. In a preferred embodiment, the systems and methods are applied to treat and ameliorate vascular injury in a transradial percutaneous access procedure and protect against underlying vascular injury; however, the systems and methods described herein may be applied to any vascular access procedure including arm or leg vascular approaches such as the femoral, brachial, dorsalis pedis or tibial blood vessels in arterial or venous line or sheath removal or trocar removal, and in hemodialysis.Type: ApplicationFiled: March 19, 2018Publication date: September 20, 2018Inventors: Matthew Hoskins, Alysha Wold, Stephanie Wiegman, Bill Shields, Simona Buergi, Simon McCarthy, Cole Gannett, Ervelyn Winata
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Publication number: 20180214160Abstract: The present invention relates to a compressive band and hemostatic dressing system and related methods of use to provide rapid, non-occlusive bleeding control, arterial injury treatment, and injury protection comfortably and reliably after vascular access procedures. The present invention may comprise some or all of the following elements: a positioner assembly, a compressive cushion component, a compression plate, a strap with a flexible hinge assembly, and a hemostatic dressing. In a preferred embodiment, the systems and methods are applied to treat and ameliorate vascular injury in a transradial percutaneous access procedure and protect against underlying vascular injury; however, the systems and methods described herein may be applied to any vascular access procedure including arm or leg vascular approaches such as the femoral, brachial, dorsalis pedis or tibial blood vessels in arterial or venous line or sheath removal or trocar removal, and in hemodialysis.Type: ApplicationFiled: January 8, 2016Publication date: August 2, 2018Inventors: Matthew Hoskins, Alysha Wold, Stephanie Wiegman, Bill Shields, Simona Buergi, Simon McCarthy, Cole Gannett, Ervelyn Winata
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Publication number: 20180193531Abstract: The invention relates to biocompatible, bioabsorbable derivatized non-crosslinked chitosan compositions optionally crosslinked to gelatin/collagen by 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride (EDC) for biomedical use and methods of making and testing such compositions, including a modified acute systemic toxicity test. The compositions comprise derivatized chitosan reacetylated to a degree of N-deacetylation (DDA) of between about 15% and 40%. The compositions are typically bioabsorbed in about 90 days or less and can be made to bioabsorb at differing rates of speed. The compositions are initially soluble in aqueous solution below pH 6.5. The compositions have an acid content that can be adjusted between about 0% (w/w) and about 8% (w/w) to customize the composition for uses that require and/or tolerate differing levels of cytotoxicity, adhesion, composition cohesion, and cell infiltration into the composition.Type: ApplicationFiled: February 13, 2018Publication date: July 12, 2018Inventors: Barbara McGrath, Simon McCarthy, Sam Kuhn, Alysha Wold, Michael Stolten, Amanda Bennett
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Publication number: 20180169134Abstract: The present invention comprises chitosan materials and methods of using carbonic acid for aqueous solubilization of neutralized or pre-treated chitosan gels and provides, among other things, substantially acid salt free composition native final forms without requiring subsequent acid salt elution. The invention includes chitosan-based solid and semi-solid material forms, optionally reinforced with chitosan fibers, such as powders, fibers, films, matrices, sponges, implants, scaffolds, fillers, and hydrogels. Native final forms are produced from chitosan powder solubilized in an aqueous acidic solution, processed to form a high pH hydrated chitosan gel precipitate material that is then neutralized by water washing and re-solubilized substantially to chitosan solution using carbonic acid.Type: ApplicationFiled: February 13, 2018Publication date: June 21, 2018Inventors: Simon McCarthy, Barbara McGrath, Sam Kuhn, Jess Kimball, Michael Stolten, Amanda Bennett
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Publication number: 20180110897Abstract: An aqueous chitosan gel system of novel non-scarring, non-interfering, transparent, stable, solubilized chitosan that controls bleeding is described herein. The aqueous chitosan gel system can comprise water, chitosan, an acid, a plasticizer, a rheology modifying agent, an antioxidant stabilizer, an alcohol, and a multi-valent salt. Additional components of the aqueous chitosan gel system can comprise a bifunctional organic acid, a tnfunctional organic acid, a multi-functional organic acid, a phosphoric acid, a polyphosphoric acid and a salt.Type: ApplicationFiled: April 11, 2016Publication date: April 26, 2018Inventors: Maggie Bush, Sam Kuhn, Simon McCarthy
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Patent number: 9925210Abstract: The present invention comprises chitosan materials and methods of using carbonic acid for aqueous solubilization of neutralized or pre-treated chitosan gels and provides, among other things, substantially acid salt free composition native final forms without requiring subsequent acid salt elution. The invention includes chitosan-based solid and semi-solid material forms, optionally reinforced with chitosan fibers, such as powders, fibers, films, matrices, sponges, implants, scaffolds, fillers, and hydrogels. Native final forms are produced from chitosan powder solubilized in an aqueous acidic solution, processed to form a high pH hydrated chitosan gel precipitate material that is then neutralized by water washing and re-solubilized substantially to chitosan solution using carbonic acid.Type: GrantFiled: February 4, 2015Date of Patent: March 27, 2018Assignee: Tricol Biomedical, Inc.Inventors: Simon McCarthy, Barbara McGrath, Sam Kuhn, Jess Kimball, Michael Stolten, Amanda Bennett
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Patent number: 9925310Abstract: The invention relates to biocompatible, bioabsorbable derivatized non-crosslinked chitosan compositions optionally crosslinked to gelatin/collagen by 1-ethyl-3-[3-dimethylaminopropyl] carbodiimide hydrochloride (EDC) for biomedical use and methods of making and testing such compositions, including a modified acute systemic toxicity test. The compositions comprise derivatized chitosan reacetylated to a degree of N-deacetylation (DDA) of between about 15% and 40%. The compositions are typically bioabsorbed in about 90 days or less and can be made to bioabsorb at differing rates of speed. The compositions are initially soluble in aqueous solution below pH 6.5. The compositions have an acid content that can be adjusted between about 0% (w/w) and about 8% (w/w) to customize the composition for uses that require and/or tolerate differing levels of cytotoxicity, adhesion, composition cohesion, and cell infiltration into the composition.Type: GrantFiled: December 6, 2016Date of Patent: March 27, 2018Assignee: Tricol Biomedical, Inc.Inventors: Barbara McGrath, Simon McCarthy, Sam Kuhn, Alysha Wold, Michael Stolten, Amanda Bennett
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Patent number: 9846163Abstract: The invention relates to biocompatible, bioabsorbable derivatized non-crosslinked chitosan compositions optionally crosslinked to gelatin/collagen by 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride (EDC) for biomedical use and methods of making and testing such compositions, including a modified acute systemic toxicity test. The compositions comprise derivatized chitosan reacetylated to a degree of N-deacetylation (DDA) of between about 15% and 40%. The compositions are typically bioabsorbed in about 90 days or less and can be made to bioabsorb at differing rates of speed. The compositions are initially soluble in aqueous solution below pH 6.5. The compositions have an acid content that can be adjusted between about 0% (w/w) and about 8% (w/w) to customize the composition for uses that require and/or tolerate differing levels of cytotoxicity, adhesion, composition cohesion, and cell infiltration into the composition.Type: GrantFiled: March 4, 2015Date of Patent: December 19, 2017Assignee: Tricol Biomedical, Inc.Inventors: Barbara McGrath, Simon McCarthy, Sam Kuhn, Alysha Wold, Michael Stolten, Amanda Bennett