Patents by Inventor Simon MOUNTFORD

Simon MOUNTFORD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SULFOXONIUM YLIDE DERIVATIVES AS PROBES FOR CYSTEINE PROTEASE
    Publication number: 20230285598
    Abstract: The present invention relates to compounds of formula I bearing a sulfoxoniumylide moiety as warhead, or salts thereof. Such compounds can be used as activity-based probes for cysteine proteases such as cathepsin X, in methods of detecting cysteine protease activity and in related diagnostic or therapeutic methods.
    Type: Application
    Filed: December 20, 2019
    Publication date: September 14, 2023
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Laura EDGINGTON-MITCHELL, Simon MOUNTFORD, Bethany M. ANDERSON, Monika SZABO, Luigi AURELIO, Philip THOMPSON
  • 4H-pyran compounds as insulin-regulated aminopeptidase (IRAP) inhibitors
    Patent number: 11306066
    Abstract: The present disclosure relates generally, but not exclusively, to compounds and their use in therapy, to compositions and agents comprising said compounds, to methods of treatment using said compounds, and their use in the manufacture of medicaments. The disclosure further relates to inhibitors of IRAP and their use in the treatment or prevention of Alzheimer's disease and the treatment and prevention of memory and cognitive disorders.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: April 19, 2022
    Assignee: Monash University
    Inventors: Siew Yeen Chai, Philip Thompson, Simon Mountford, Michael W. Parker
  • 4H-Pyran Compounds as Insulin-Regulated Aminopeptidase (IRAP) Inhibitors
    Publication number: 20180170891
    Abstract: The present disclosure relates generally, but not exclusively, to compounds and their use in therapy, to compositions and agents comprising said compounds, to methods of treatment using said compounds, and their use in the manufacture of medicaments. The disclosure further relates to inhibitors of IRAP and their use in the treatment or prevention of Alzheimer's disease and the treatment and prevention of memory and cognitive disorders.
    Type: Application
    Filed: May 6, 2016
    Publication date: June 21, 2018
    Applicants: Monash University, The Florey Institute of Neuroscience and Mental Health, St. Vincent's Institute of Medical Research
    Inventors: Siew Yeen CHAI, Philip THOMPSON, Simon MOUNTFORD, Michael W. PARKER