Patents by Inventor Simon Murray Cooper

Simon Murray Cooper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aerosol formulations of salmeterol xinafoate
    Patent number: 6613307
    Abstract: The present invention relates to formulations comprising particulate products which may be prepared by methods and apparatus using supercritical fluids. More particularly, the invention relates to formulations comprising certain crystalline forms of 4-hydroxy-&agr;1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol (salmeterol) 1-hydroxy-2-naphthalenecarboxylate (xinafoate). Accordingly, the present invention provides an aerosol pharmaceutical formulation comprising salmeterol xinafoate with a controlled particle size, shape and morphology, and a fluorocarbon, hydrogen-containing fluorocarbon or hydrogen-containing chlorofluorocarbon propellant.
    Type: Grant
    Filed: October 5, 2000
    Date of Patent: September 2, 2003
    Assignee: SmithKline Beecham Corporation
    Inventor: Simon Murray Cooper
  • Orthorhombic crystalline form of fluticasone propionate and pharmaceutical compositions thereof
    Patent number: 6406718
    Abstract: The invention relates to a new polymorphic crystalline form of S-fluoromethyl 6&agr;,9&agr;-difluoro-11&bgr;-hydroxy-16&agr;-methyl-3-oxo-17&agr;-propionyloxyandrosta-1,4-diene-17&bgr;-carbothiate (fluticasone propionate). The new polymorphic crystalline form is easily handled and easily fluidised and its particle size and shape can be controlled. The invention also relates to the use of this new material in therapy, particularly in the treatment of respiratory disorders, e.g. asthma.
    Type: Grant
    Filed: April 15, 1999
    Date of Patent: June 18, 2002
    Assignee: SmithKline Beecham Corporation
    Inventor: Simon Murray Cooper