Patents by Inventor Simon N. Haydar

Simon N. Haydar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolopyridinone compounds and methods for treating HIV
    Patent number: 9012642
    Abstract: Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the retrovirus family of viruses such as the Human Immunodeficiency Virus (HIV).
    Type: Grant
    Filed: September 18, 2012
    Date of Patent: April 21, 2015
    Assignee: ViiV Healthcare UK Limited
    Inventors: Simon N. Haydar, Brian Alvin Johns, Emile Johann Velthuisen
  • Pyrrolopyridinone Compounds And Methods For Treating HIV
    Publication number: 20140343092
    Abstract: Provided are compounds and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the retrovirus family of viruses such as the Human Immunodeficiency Virus (HIV).
    Type: Application
    Filed: September 18, 2012
    Publication date: November 20, 2014
    Inventors: Simon N. Haydar, Brian Alvin Johns, Emile Johann Velthuisen
  • Modulators of ?7 nicotinic acetylcholine receptors and therapeutic uses thereof
    Patent number: 8163729
    Abstract: The present invention provides compounds of formula (I) and compositions thereof, methods of making them, and methods of using them to modulate alpha7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory system.
    Type: Grant
    Filed: January 16, 2008
    Date of Patent: April 24, 2012
    Assignees: Wyeth, Siena Biotech S.p.A.
    Inventors: Chiara Ghiron, Arianna Nencini, Iolanda Micco, Riccardo Zanaletti, Laura Maccari, Hendrick Bothmann, Simon N. Haydar, Maurizio Varrone, Carmela Pratelli, Boyd L. Harrison
  • ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR INHIBITORS
    Publication number: 20100130474
    Abstract: The present invention provides compounds and compositions, methods of making them, and methods of using them to modulate ?7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory systems.
    Type: Application
    Filed: July 16, 2009
    Publication date: May 27, 2010
    Applicants: WYETH, SIENA BIOTECH S.P.A.
    Inventors: Hendrick Bothmann, Chiara Ghiron, Laura Maccari, Iolanda Micco, Arianna Nencini, Riccardo Zanaletti, Simon N. Haydar
  • MODULATORS OF ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTORS AND THERAPEUTIC USES THEREOF
    Publication number: 20100029606
    Abstract: The present invention provides compounds of formula (I) and compositions thereof, methods of making them, and methods of using them to modulate alpha7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory system.
    Type: Application
    Filed: January 16, 2008
    Publication date: February 4, 2010
    Applicants: WYETH, SIENA BIOTECH S.P.A.
    Inventors: Chiara Ghiron, Arianna Nencini, Iolanda Micco, Riccardo Zanaletti, Laura Maccari, Hendrick Bothmann, Simon N. Haydar, Maurizio Varrone, Carmela Pratelli, Boyd L. Harrison
  • ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR INHIBITORS
    Publication number: 20100016360
    Abstract: The present invention provides compounds and compositions, methods of making them, and methods of using them to modulate ?7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory system.
    Type: Application
    Filed: July 16, 2009
    Publication date: January 21, 2010
    Applicants: WYETH, SIENA BIOTECH S.P.A.
    Inventors: Simon N. Haydar, Chiara Ghiron, Michela Valacchi, Ugo Zanelli
  • ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR INHIBITORS
    Publication number: 20100016598
    Abstract: The present invention provides compounds and compositions, methods of making them, and methods of using them to modulate ?7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory system.
    Type: Application
    Filed: July 16, 2009
    Publication date: January 21, 2010
    Applicants: WYETH, SIENA BIOTECH S.P.A.
    Inventors: Michela Valacchi, Simon N. Haydar
  • ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR INHIBITORS
    Publication number: 20100016343
    Abstract: The present invention provides compounds and compositions, methods of making them, and methods of using them to modulate ?7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory system.
    Type: Application
    Filed: July 16, 2009
    Publication date: January 21, 2010
    Applicants: WYETH, SIENA BIOTECH S.P.A.
    Inventors: Chiara Ghiron, Michela Valacchi, Ugo Zanelli, Simon N. Haydar
  • INDOLE, BENZIMIDAZOLE, AND BENZOLACTAM BORONIC ACID COMPOUNDS, ANALOGS THEREOF AND METHODS OF USE THEREOF
    Publication number: 20090264384
    Abstract: Benzimidazole, indole and benzolactam boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-?) in a subject in need thereof.
    Type: Application
    Filed: November 10, 2008
    Publication date: October 22, 2009
    Applicant: Nuada, Inc.
    Inventors: John R. Didsbury, Tatyana Dyakonov, Simon N. Haydar, Michael L. Jones, Francine F. Li, Christopher J. Markworth, Jessy Matthew, Frank J. Schoenen, Jan J. Scicinski, David Middlemiss, James F. Burns, Leonard A. Cabana, Glenn C. Collupy, David N. Vanvliet
  • COMPOUNDS USEFUL AS ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS
    Publication number: 20090181952
    Abstract: The present invention provides compounds and compositions, and methods of using them to modulate ?7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory systems.
    Type: Application
    Filed: January 14, 2009
    Publication date: July 16, 2009
    Applicants: Wyeth, Siena Biotech S.p.A.
    Inventors: Simon N. Haydar, Riccardo Zanaletti
  • Cyclosporins
    Patent number: 7538084
    Abstract: The compounds of the present invention are represented by the chemical structure found in Formula I: Formula I where A is an amino acid of Formula II: or a pharmaceutically acceptable salt thereof, with R0, R1, B, C, D, E, F, G, H, I, J, and K defined herein.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: May 26, 2009
    Assignee: AMR Technology, Inc.
    Inventors: Bruce F. Molino, Simon N. Haydar, Zhicai Yang, Peter C. Michels, Michael S. Hemenway, Joseph O. Rich, Yuri Khmelnitsky
  • Compounds and Methods of Use Thereof
    Publication number: 20090005344
    Abstract: Imidazole and benzimidazole boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-?) in a subject in need thereof.
    Type: Application
    Filed: October 27, 2005
    Publication date: January 1, 2009
    Applicant: NKUADA, LLC
    Inventors: James F. Burns, Leonardo A. Cabana, Glenn C. Collupy, John R. Didsbury, Tatyana A. Dyakonov, Simon N. Haydar, Michael L. Jones, Francine F. Li, Christopher J. Markworth, Jessymol Mathew, Frank J. Schoenen, David S. Van Vliet, David Middlemiss
  • Compounds and Methods of Use Thereof
    Publication number: 20080319044
    Abstract: Indole boronic acid compounds, and analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-?) in a subject in need thereof.
    Type: Application
    Filed: October 27, 2005
    Publication date: December 25, 2008
    Applicant: NUADA, LLC
    Inventors: John R. Didsbury, Tatyana A. Dyakonov, Simon N. Haydar, Michael L. Jones, Francine F. Li, Christopher J. Markworth, Jessymol Mathew, Frank J. Schoenen, Jan J. Scicinski, David Middlemiss
  • Small organic molecule regulators of cell proliferation
    Publication number: 20080194637
    Abstract: The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a compound. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal patched pathway or agonizing smoothened or hedgehog activity.
    Type: Application
    Filed: November 2, 2007
    Publication date: August 14, 2008
    Applicants: Curis, Inc., Wyeth
    Inventors: Shirley Ann Brunton, Oivin M. Guicherit, Simon N. Haydar, Lawrence I. Kruse, Dane Springer
  • Novel cyclosporins
    Publication number: 20040235716
    Abstract: The compounds of the present invention are represented by the chemical structure found in Formula I: 1 Formula I 1
    Type: Application
    Filed: March 16, 2004
    Publication date: November 25, 2004
    Inventors: Bruce F. Molino, Simon N. Haydar, Zhicai Yang, Peter C. Michels, Michael S. Hemenway, Joseph O. Rich, Yuri Khmelnitsky
  • Aza-benzothiopyranoindazoles with antitumor activity
    Patent number: 6747039
    Abstract: The present invention relates to a group of aza-anthrapyrazole compounds having antitumor activity, and processes for their preparation. Compositions containing the aza-anthrapyrazole compounds and methods of treating tumors and cancer in mammals with the compounds of the present invention are also disclosed.
    Type: Grant
    Filed: March 12, 2002
    Date of Patent: June 8, 2004
    Assignee: Albany Molecular Research, Inc.
    Inventor: Simon N. Haydar
  • Aza-benzothiopyranoindazoles with antitumor activity
    Publication number: 20030225069
    Abstract: The present invention relates to a group of aza-anthrapyrazole compounds having antitumor activity, and processes for their preparation. Compositions containing the aza-anthrapyrazole compounds and methods of treating tumors and cancer in mammals with the compounds of the present invention are also disclosed.
    Type: Application
    Filed: March 12, 2002
    Publication date: December 4, 2003
    Inventor: Simon N. Haydar
  • Aza-thioxanthenones with antitumor activity
    Publication number: 20030212061
    Abstract: The present invention relates to a group of aza-thioxanthenone compounds having antitumor activity, and processes for their preparation. Compositions containing the aza-thioxanthenone compounds and methods of treating tumors and cancer in mammals with the compounds of the present invention are also disclosed.
    Type: Application
    Filed: March 12, 2002
    Publication date: November 13, 2003
    Inventor: Simon N. Haydar