Patents by Inventor Simon N. Pimstone

Simon N. Pimstone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and reagents for modulating cholesterol levels
    Patent number: 8715968
    Abstract: The invention features ABC1 nucleic acids and polypeptides for the diagnosis and treatment of abnormal cholesterol regulation. The invention also features methods for identifying compounds for modulating cholesterol levels in an animal (e.g., a human).
    Type: Grant
    Filed: December 23, 2003
    Date of Patent: May 6, 2014
    Assignee: Xenon Pharmaceuticals Inc.
    Inventors: Michael R. Hayden, Angela R. Brooks-Wiison, Simon N. Pimstone
  • Polynucleotide encoding an ATP binding cassette transporter 1 (ABC1) polypeptide
    Patent number: 8067219
    Abstract: The invention features ABC1 nucleic acids and polypeptides for the diagnosis and treatment of abnormal cholesterol regulation. The invention also features methods for identifying compounds for modulating cholesterol levels in an animal (e.g., a human).
    Type: Grant
    Filed: September 14, 2010
    Date of Patent: November 29, 2011
    Assignees: Xenon Pharmaceuticals Inc., University of British Columbia
    Inventors: Michael R. Hayden, Angela R. Brooks-Wilson, Simon N. Pimstone
  • Methods and reagents for modulating cholesterol levels
    Publication number: 20110065147
    Abstract: The invention features ABC1 nucleic acids and polypeptides for the diagnosis and treatment of abnormal cholesterol regulation. The invention also features methods for identifying compounds for modulating cholesterol levels in an animal (e.g., a human).
    Type: Application
    Filed: September 14, 2010
    Publication date: March 17, 2011
    Inventors: Michael R. Hayden, Angela R. Brooks-Wilson, Simon N. Pimstone
  • Methods and reagents for modulating cholesterol levels
    Patent number: 7785886
    Abstract: The invention features ABC1 nucleic acids and polypeptides for the diagnosis and treatment of abnormal cholesterol regulation. The invention also features methods for identifying compounds for modulating cholesterol levels in an animal (e.g., a human).
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: August 31, 2010
    Assignees: Xenon Pharmaceuticals, Inc., Univ. of British Columbia
    Inventors: Michael R. Hayden, Angela R. Brooks-Wilson, Simon N. Pimstone
  • Compositions and methods for modulating HDL cholesterol and triglyceride levels
    Publication number: 20040229275
    Abstract: The invention features methods for treating patients having low HDL, a higher than normal triglyceride level, or a cardiovascular disease by administering compounds that modulate ABC1 expression or activity.
    Type: Application
    Filed: June 18, 2004
    Publication date: November 18, 2004
    Inventors: Michael R. Hayden, Angela R. Brooks-Wilson, Simon N. Pimstone, Susanne M. Clee
  • Methods and reagents for modulating cholesterol levels
    Publication number: 20040185508
    Abstract: The invention features ABC1 nucleic acids and polypeptides for the diagnosis and treatment of abnormal cholesterol regulation. The invention also features methods for identifying compounds for modulating cholesterol levels in an animal (e.g., a human).
    Type: Application
    Filed: April 28, 2004
    Publication date: September 23, 2004
    Inventors: Michael R. Hayden, Angela R. Brooks-Wilson, Simon N. Pimstone
  • Methods and reagents for modulating cholesterol levels
    Publication number: 20040157250
    Abstract: The invention features ABC1 nucleic acids and polypeptides for the diagnosis and treatment of abnormal cholesterol regulation. The invention also features methods for identifying compounds for modulating cholesterol levels in an animal (e.g., a human).
    Type: Application
    Filed: December 23, 2003
    Publication date: August 12, 2004
    Inventors: Michael R. Hayden, Angela R. Brooks-Wiison, Simon N. Pimstone
  • Compositions and methods for modulating HDL cholesterol and triglyceride levels
    Publication number: 20040137423
    Abstract: The invention provides methods for identifying agents that modulate HDL-levels in animals by evaluating the ability of LXR-modulating agents to increase ABCA1-gene expression in a cell as well as using such agents to treat conditions involving lower than normal HDL-levels, higher than normal triglyceride levels and the like.
    Type: Application
    Filed: December 23, 2003
    Publication date: July 15, 2004
    Inventors: Michael R. Hayden, Angela R. Brooks-Wilson, Simon N. Pimstone, Susanne M. Clee
  • Methods and reagents for modulating cholesterol levels
    Publication number: 20040058869
    Abstract: The invention features ABC1 nucleic acids and polypeptides for the diagnosis and treatment of abnormal cholesterol regulation. The invention also features methods for identifying compounds for modulating cholesterol levels in an animal (e.g., a human).
    Type: Application
    Filed: July 10, 2003
    Publication date: March 25, 2004
    Inventors: Michael R. Hayden, Angela R. Brooks Wilson, Simon N. Pimstone
  • Methods and reagents for modulating cholesterol levels
    Publication number: 20040005666
    Abstract: The invention features ABC1 nucleic acids and polypeptides for the diagnosis and treatment of abnormal cholesterol regulation. The invention also features methods for identifying compounds for modulating cholesterol levels in an animal (e.g., a human).
    Type: Application
    Filed: June 2, 2003
    Publication date: January 8, 2004
    Inventors: Michael R. Hayden, Angela R. Brooks-Wiison, Simon N. Pimstone
  • Process for identifying modulators of ABC1 activity
    Patent number: 6617122
    Abstract: The invention features ABC1 nucleic acids and polypeptides for the diagnosis and treatment of abnormal cholesterol regulation. The invention also features methods for identifying compounds for modulating cholesterol levels in an animal (e.g., a human).
    Type: Grant
    Filed: March 15, 2000
    Date of Patent: September 9, 2003
    Assignee: Xenon Genetics, Inc.
    Inventors: Michael R. Hayden, Angela R. Brooks-Wiison, Simon N. Pimstone