Patents by Inventor Simon P. MacKay

Simon P. MacKay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IKK INHIBITORS
    Publication number: 20250304576
    Abstract: The present invention relates to IKK-alpha inhibitory compounds, or a pharmaceutically acceptable salts, hydrates or solvates thereof, having the structural Formula (I), shown below: wherein R1, X, R3 R4 and X1 are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which IKK-alpha activity is implicated.
    Type: Application
    Filed: May 11, 2023
    Publication date: October 2, 2025
    Inventors: Simon P. MacKay, Aisha A. Alsfouk, Usama Ammar, Nahoum G. Anthony, Jessica Baiget, Giacomo Berretta, David Breen, Judith Huggan, Christopher Lawson, Domiziana Masci, Sabin Llona-Minguez, Christopher Riley, Colin J. Suckling, Christopher West