Patents by Inventor Simon Patrick Keiser

Simon Patrick Keiser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES BINDING TO HLA-A2/MAGE-A4
    Publication number: 20260098095
    Abstract: The present invention generally relates to antibodies that bind to HLA-A2/MAGE-A4, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.
    Type: Application
    Filed: September 16, 2025
    Publication date: April 9, 2026
    Inventors: Tina WEINZIERL, Lydia Jasmin HANISCH, Alexander BUJOTZEK, Alejandro CARPY GUTIERREZ CIRLOS, Stefan KLOSTERMANN, Christian KLEIN, Simon Patrick KEISER, Tanja FAUTI, Estelle MARRER-BERGER, Pablo UMAÑA
  • ANTIBODIES BINDING TO HLA-A2/MAGE-A4
    Publication number: 20240383987
    Abstract: The present invention generally relates to antibodies that bind to HLA-A2/MAGE-A4, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.
    Type: Application
    Filed: April 17, 2024
    Publication date: November 21, 2024
    Inventors: Tina WEINZIERL, Lydia Jasmin HANISCH, Alexander BUJOTZEK, Alejandro CARPY GUTIERREZ CIRLOS, Stefan KLOSTERMANN, Christian KLEIN, Simon Patrick KEISER, Tanja FAUTI, Estelle MARRER-BERGER, Pablo UMAÑA
  • TREATMENT OF CANCER USING A HLA-A2/MAGE-A4 X CD3 BISPECIFIC ANTIBODY AND A 4-1BB (CD137) AGONIST
    Publication number: 20240316193
    Abstract: The present invention relates to the treatment of cancer, in particular to the treatment of cancer using a HLA-A2/MAGE-A4×CD3 bispecific antibody and a 4-1BB (CD137) agonist.
    Type: Application
    Filed: June 13, 2024
    Publication date: September 26, 2024
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Simon Patrick KEISER, Tina WEINZIERL
  • Antibodies binding to HLA-A2/MAGE-A4
    Patent number: 11987632
    Abstract: The present invention generally relates to antibodies that bind to HLA-A2/MAGE-A4, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: May 21, 2024
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Tina Weinzierl, Lydia Jasmin Hanisch, Alexander Bujotzek, Alejandro Carpy Gutierrez Cirlos, Stefan Klostermann, Christian Klein, Simon Patrick Keiser, Tanja Fauti, Estelle Marrer-Berger, Pablo Umaña
  • Antibodies binding to HLA-A2/MAGE-A4
    Publication number: 20210230278
    Abstract: The present invention generally relates to antibodies that bind to HLA-A2/MAGE-A4, including multispecific antibodies e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.
    Type: Application
    Filed: December 17, 2020
    Publication date: July 29, 2021
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Tina Weinzierl, Lydia Jasmin Hanisch, Alexander Bujotzek, Alejandro Carpy Gutierrez Cirlos, Stefan Klostermann, Christian Klein, Simon Patrick Keiser, Tanja Fauti, Estelle Marrer-Berger, Pablo Umaña