Patents by Inventor Simon PAUL

Simon PAUL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9290496
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, G, ring A, ring B, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, and m are defined herein. The novel purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: March 22, 2016
    Assignee: PFIZER INC.
    Inventors: Douglas Carl Behenna, Hengmiao Cheng, Sujin Cho-Schultz, Theodore Otto Johnson, Jr., John Charles Kath, Asako Nagata, Sajiv Krishnan Nair, Simon Paul Planken
  • Patent number: 9274862
    Abstract: Among other things, at a client computer system in communication with a computer network, a request object is generated that includes logic to control the handling of requests. At least one of the requests depends on (for example, simply by being part of a sequence) a result of at least one of the other of the requests. The request object is sent to a server computer system that is in communication with the computer network. A response object is received that includes results of at least some of the requests.
    Type: Grant
    Filed: December 9, 2010
    Date of Patent: March 1, 2016
    Assignee: Mimecast North America Inc.
    Inventors: Neil Hamilton Murray, Simon Paul Tyler
  • Patent number: 9222062
    Abstract: A cleaning composition comprising at least one fatty acid of a sarcosine, and at least one fatty acid of an amino acid, and/or salts thereof. There is also provided an end-use cleaning formulation comprising said cleaning composition having been diluted to 0.2 wt. % to 10 wt. %, and a method of treating a hard surface comprising applying the cleaning composition or the cleaning formulation. The cleaning composition or cleaning formulation are suitable for use in providing soil resistance to a hard surface.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: December 29, 2015
    Assignee: CRODA INTERNATIONAL PLC
    Inventors: Stephen Dominic Johnson, Simon Paul Flavin, Peter Michael Murphy, Mahzad Goodwin
  • Publication number: 20150329990
    Abstract: The present invention relates to a method of washing animal fibers comprising contacting the animal fibers with a surfactant composition comprising a mixture of alcohol ethoxylate surfactants and optionally at least one propoxylated surfactant.
    Type: Application
    Filed: December 10, 2013
    Publication date: November 19, 2015
    Applicant: CRODA INTERNATIONAL PLC
    Inventors: Mahzad GOODWIN, Peter Michael MURPHY, Simon Paul FLAVIN
  • Publication number: 20150237018
    Abstract: A method for securely configuring a customer premise equipment in a network. The network including a configuration server, a DHCP server, and the customer premise equipment. The method includes receiving a request from the customer premise equipment for leasing an Internet Protocol (IP) address to the customer premise equipment. The method further includes embedding at least a portion of a Media Access Control (MAC) address of the customer premise equipment into the IP address leased to the customer premise equipment. The method includes leasing the IP address to the customer premise equipment. Further, the method enables authentication of customer premise equipment, before providing configuration to the customer premise equipment. The method includes use of characteristic attributes of the customer premise equipment to generate cryptographic keys for secure connection.
    Type: Application
    Filed: February 18, 2014
    Publication date: August 20, 2015
    Applicant: Ciena Corporation
    Inventors: Simon Paul PARRY, James Alexander Ivens HOLTOM
  • Publication number: 20150204042
    Abstract: The present invention relates to a ground stabilisation system and a support and a method of stabilising ground, more particularly to soil below a building or foundation of a structure. A system for soil consolidation is disclosed. It comprises: a delivery channel (10) that is closed at one end and adapted to receive a grout or resinous liquid (99). The delivery channel (10) has a plurality of apertures (20) that are selectively openable and closable, ideally by way of a concentric member (40) in order to permit filler or resinous material (99) to exude/egress from the delivery channel (10) into selected regions of surrounding soil at desired times, in a controllable manner, so as to create a stabilised volume of soil bonded to the delivery channel.
    Type: Application
    Filed: July 22, 2013
    Publication date: July 23, 2015
    Inventor: Simon Paul Collis
  • Publication number: 20150203502
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, T, V, W, X, Y, Z, ring A, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17 and m are defined herein. There novel pyrrolopyrimidine and purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
    Type: Application
    Filed: March 31, 2015
    Publication date: July 23, 2015
    Inventors: Hengmiao CHENG, Theodore Otto JOHNSON, JR., John Charles KATH, Kevin Kun-Chin LIU, Elizabeth Ann LUNNEY, Asako NAGATA, Sajiv Krishnan NAIR, Simon Paul PLANKEN, Scott Channing SUTTON
  • Patent number: 9056865
    Abstract: The present application relates to compounds of Formula (I), and Formula (II), or pharmaceutically acceptable salt thereof, wherein A, X, Y, Z, e, f, R1, R2, R3, R4, R5, R5b, R6, R7, R8, R9, R10, R11, R20, R21, R22 and R23 are defined herein. These novel pyridine derivatives that are useful in therapy, in particular for treating diseases or conditions mediated by Smo, including the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to methods of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: June 16, 2015
    Assignee: Pfizer Inc.
    Inventors: Sajiv Krishnan Nair, Simon Paul Planken
  • Publication number: 20150150651
    Abstract: A dental wedge for inserting into the interproximal space between adjacent teeth comprises a first and second sidewall comprised of a shape memory material, including a nickel-titanium alloy, wherein the dental wedge is in a first, resting state when outside of the interproximal space and transforms to a second, operational state when the dental wedge is interested into the interproximal space between adjacent teeth and exposed to a first transformation stimulus, namely exposure to the higher temperature in the interproximal space. The expansion force generated by the dental wedge when in the second, operational stage is sufficient to secure a dental matrix against the tooth being restored and to separate the tooth being restored and adjacent tooth to expand the interproximal space.
    Type: Application
    Filed: November 28, 2014
    Publication date: June 4, 2015
    Applicant: DENTSPLY International Inc.
    Inventor: Simon Paul MCDONALD
  • Publication number: 20150152585
    Abstract: The present invention provides a cleaning apparatus for cleaning at least one soiled substrate with a multiplicity of solid particles, the apparatus comprising: an external casing defining the external perimeter of the apparatus, said external casing defining at least an upper internal volume and a lower internal volume; a perforate drum arranged in the upper internal volume and configured for rotation about a horizontal axis, for agitation of the at least one soiled substrate during a cleaning process; a partition sealingly dividing the upper internal volume from the lower internal volume, the partition including a collecting region configured to collect and retain wash liquor and solid particles of said multiplicity of solid particles released from the drum during a cleaning process; a recirculating arrangement configured to transfer particles of said multiplicity of solid particles from said collecting region to said drum; wherein an internal surface of a wall of said external casing arranged substantially
    Type: Application
    Filed: November 21, 2014
    Publication date: June 4, 2015
    Inventors: Michael David SAWFORD, Simon Paul WELLS
  • Patent number: 9040547
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, T, V, W, X, Y, Z, ring A, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17 and m are defined herein. There novel pyrrolopyrimidine and purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: May 26, 2015
    Assignee: PFIZER INC.
    Inventors: Hengmiao Cheng, Theodore Otto Johnson, Jr., John Charles Kath, Kevin Kun-Chin Liu, Elizabeth Ann Lunney, Asako Nagata, Sajiv Krishnan Nair, Simon Paul Planken, Scott Channing Sutton
  • Publication number: 20150141402
    Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, G, ring A, ring B, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, and m are defined herein. The novel purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
    Type: Application
    Filed: November 20, 2014
    Publication date: May 21, 2015
    Applicant: PFIZER INC.
    Inventors: Douglas Carl Behenna, Hengmiao Cheng, Sujin Cho-Schultz, Theodore Otto Johnson, JR., John Charles Kath, Asako Nagata, Sajiv Krishnan Nair, Simon Paul Planken
  • Publication number: 20150128358
    Abstract: A method for cleaning at least one soiled substrate in a rotatably mounted cylindrical drum of a cleaning apparatus with a multiplicity of solid particles comprising the steps of: a) agitating said at least one soiled substrate in said drum with wash liquor and said multiplicity of solid particles for a first cleaning cycle wherein said wash liquor comprises at least one cleaning agent; b) draining said wash liquor from said cleaning apparatus; and c) introducing an aqueous non-detergent medium into said cleaning apparatus and agitating said at least one soiled substrate with said multiplicity of solid particles in said drum for a second cleaning cycle.
    Type: Application
    Filed: November 10, 2014
    Publication date: May 14, 2015
    Inventors: Simon Paul WELLS, Michael SAWFORD, Wayne Robert SZYMCZYK, Elizabeth Jean ABERCROMBIE, Stephen Derek JENKINS
  • Publication number: 20150096128
    Abstract: A door for providing access to a rotatably mounted drum of a cleaning apparatus, the door having a flow pathway for wash liquor and a multiplicity of solid particles and a separator, the separator being arranged to direct the multiplicity of solid particles from the flow pathway into the drum and wherein the separator is further arranged to direct a portion of the wash liquor from the flow pathway to a location other than into the drum.
    Type: Application
    Filed: October 3, 2014
    Publication date: April 9, 2015
    Inventors: Michael David Sawford, Simon Paul Wells, Gareth Evan Lyn Jones
  • Publication number: 20150085672
    Abstract: A system method and device for evaluating the Quality of Service (QoS) performance of mobile telephone devices in the concurrent performance of different services through a mobile telephone network is provided. In one embodiment, the method comprises establishing a first logical communication channel via the mobile telephone network, communicating first information over the first logical communication channel, establishing a second logical communication channel over a communication network, concurrently with said communicating first information, communicating second information over the second logical communication channel, and determining a plurality of service quality metrics for the first and second information communicated over the first and second logical communication channel.
    Type: Application
    Filed: December 3, 2014
    Publication date: March 26, 2015
    Applicant: SPIRENT COMMUNICATIONS, INC.
    Inventors: Dimitrios M. Topaltzas, Jeffrey Horner, Carl Magnus Lidman, Jonathan Patrick O'Keefe, Andrea Holt, Evan Henry, Simon Paul Bone, Lauren Belella
  • Patent number: 8979530
    Abstract: A reusable dental impression tray having a reusable rigid tray holder with opposing sidewalls spaced apart substantially a first distance, a connector at a distal end of the tray holder couples the sidewalls together, the sidewalls and connector define an inward facing surface, a channel formed in and extends along the inward facing surface, and a disposable mesh bite tray having a generally U-shaped frame having an open end and a closed end, the U-shaped frame is made of a flexible material wherein the U-shaped frame has a static shape having a width at the closed end substantially the first distance and a width at the open end which is greater than the first distance, wherein with the U-shaped frame received in the channel, the open and of the U-shaped frame is held with the open end having a compressed width substantially the same as the first distance.
    Type: Grant
    Filed: September 29, 2011
    Date of Patent: March 17, 2015
    Assignee: DENTSPLY International Inc.
    Inventor: Simon Paul McDonald
  • Publication number: 20150053229
    Abstract: Method for colouring hair wherein a non-diluted hair colouring composition is applied to the hair, e.g. the hair roots and a diluted hair colouring composition is applied to the hair, e.g. the hair lengths and tips, wherein a dilutant composition comprising water and/or a non-aqueous liquid is added to the non-diluted hair colouring composition to obtain the diluted hair colouring composition.
    Type: Application
    Filed: August 21, 2014
    Publication date: February 26, 2015
    Inventors: Christoph Hans Peter BONAUER, Nan WANG, Simon Paul GODFREY
  • Patent number: 8960205
    Abstract: A method of imparting hair strand effects may include identifying each of a plurality of hair strands to which to apply a hair strand effect product independently and individually, the plurality of hair strands associated with an illustration of at least one type of hair strand effects and one of a plurality of hair styles, and applying the product to each of the plurality of hair strands independently and individually subsequent to identifying the plurality of hair strands. In the alternative or in combination, a hair instruction guide may be consulted, the guide having at least one strand size associated with one of the plurality of types of hair strand effects, and a strand of hair may be identified according to the at least one strand size. A system for creating a hair strand effect may include a hair strand effect product and such a hair instruction guide.
    Type: Grant
    Filed: August 2, 2013
    Date of Patent: February 24, 2015
    Assignee: The Procter & Gamble Company
    Inventors: Dennis Joseph Boyle, Natasha Jane Evans, Betsy Charlotte Fields, Simon Paul Godfrey, Mark Thomas Lund, Emily Joyce Ma, John Edward Sheppard, John Wallace Smith
  • Publication number: 20150032827
    Abstract: Among other things, we describe techniques for encoding data that is included in electronic communications. In one aspect, a first electronic communication system sends, to an entity, a first email message that includes a Message-ID field including data that identifies an action to be carried out by a second electronic communication system. The first electronic communication system receives, from the entity, a second email message that includes an In-Reply-To field containing the data that identifies the action to be carried out by the second electronic communication system. The first electronic communication extracts the data from the In-Reply-To field in a message header of the first electronic communication. The second electronic communication system may be the same as the first electronic communication system, or may be an electronic communication system other than the first electronic communication system.
    Type: Application
    Filed: July 25, 2013
    Publication date: January 29, 2015
    Applicant: Mimecast North America Inc.
    Inventors: Simon Paul Tyler, Jackie Anne Maylor
  • Patent number: 8931361
    Abstract: An electric vehicle transmission, the transmission comprising an input shaft arranged to be driven by an electric motor, an output shaft arranged to transfer drive from the input shaft to driving wheels of the vehicle to which the transmission is fitted, a first clutch for engaging/disengaging a first gear ratio of the transmission, a second clutch for engaging/disengaging a second gear ratio of the transmission, and a fluid pump driven in response to rotation of the output shaft, wherein the first clutch is biased to engage said first gear ratio in the absence of pressure from the fluid pump.
    Type: Grant
    Filed: February 4, 2011
    Date of Patent: January 13, 2015
    Assignee: NT Consulting International Pty Limited
    Inventor: Simon Paul Fitzgerald