Patents by Inventor Simon Peter Harold Mee

Simon Peter Harold Mee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aminohydroxylation of alkenes
    Patent number: 8987504
    Abstract: The invention relates to a process for the aminohydroxylation of alkenes using N-oxycarbamate reagents, e.g. N-acyloxycarbamate, N-alkyloxycarbonyloxycarbamate and N-aralkoxycarbonyloxycarbamate reagents. The invention particularly relates to an intermolecular aminohydroxylation reaction that can be carried out in the absence of added base. The invention also relates to novel N-oxycarbamate reagents that are stable crystalline materials. The process of the invention is useful in the synthesis of compounds having a vicinal amino alcohol moiety, such as biologically active compounds.
    Type: Grant
    Filed: June 20, 2011
    Date of Patent: March 24, 2015
    Assignee: Victoria Link Limited
    Inventors: Simon Peter Harold Mee, Andreas Luxenburger, Lawrence Daniel Harris
  • AMINOHYDROXYLATION OF ALKENES
    Publication number: 20130274479
    Abstract: The invention relates to a process for the aminohydroxylation of alkenes using N-oxycarbamate reagents, e.g. N-acyloxycarbamate, N-alkyloxycarbonyloxycarbamate and N-aralkoxycarbonyloxycarbamate reagents. The invention particularly relates to an intermolecular aminohydroxylation reaction that can be carried out in the absence of added base. The invention also relates to novel N-oxycarbamate reagents that are stable crystalline materials. The process of the invention is useful in the synthesis of compounds having a vicinal amino alcohol moiety, such as biologically active compounds.
    Type: Application
    Filed: June 20, 2011
    Publication date: October 17, 2013
    Applicant: INDUSTRIAL RESEARCH LIMITED
    Inventors: Simon Peter Harold Mee, Andreas Luxenburger, Lawrence Daniel Harris
  • Inhibitors of nucleoside phosphorylases and nucleosidases
    Publication number: 20090233948
    Abstract: The present invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNP), purine phosphoribosyltransferases (PPRT), 5?-methylthioadenosine phosphorylases (MTAP), 5?-methylthioadenosine nucleosidases (MTAN) and/or nucleoside hydrolases (NH). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.
    Type: Application
    Filed: May 22, 2006
    Publication date: September 17, 2009
    Inventors: Gary Brian Evans, Richard Hubert Furneaux, Vern L. Schramm, Peter Charles Tyler, Simon Peter Harold Mee, Olga Vladimirovna Zubkova