Patents by Inventor Simon-Peter WILLIAMS

Simon-Peter WILLIAMS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-CD8 ANTIBODIES AND USES THEREOF
    Publication number: 20240018241
    Abstract: Provided are anti-CD8 antibodies that bind human CD8 and do not stimulate or inhibit the activation of CD8+ T cells. Also provided are nucleic acids encoding such anti-CD8 antibodies, vectors comprising such nucleic acids, host cells comprising same, and methods of making such anti-CD8 antibodies. Also provided are anti-CD8 antibodies conjugated to a detectable label. Provided are methods of using such anti-CD8 antibodies to detect CD8+ T cells in a subject, monitor disease progress in a subject having cancer, and monitor treatment progress in a subject having cancer.
    Type: Application
    Filed: June 30, 2023
    Publication date: January 18, 2024
    Applicant: Genentech, Inc.
    Inventors: Yvonne M. CHEN, Eugene Yu-Chuan CHIANG, Jane Louise GROGAN, Simon-Peter WILLIAMS, Matthew Lawrence ALBERT
  • Anti-CD8 antibodies and uses thereof
    Patent number: 11739150
    Abstract: Provided are anti-CD8 antibodies that bind human CD8 and do not stimulate or inhibit the activation of CD8+ T cells. Also provided are nucleic acids encoding such anti-CD8 antibodies, vectors comprising such nucleic acids, host cells comprising same, and methods of making such anti-CD8 antibodies. Also provided are anti-CD8 antibodies conjugated to a detectable label. Provided are methods of using such anti-CD8 antibodies to detect CD8+ T cells in a subject, monitor disease progress in a subject having cancer, and monitor treatment progress in a subject having cancer.
    Type: Grant
    Filed: February 11, 2020
    Date of Patent: August 29, 2023
    Assignee: Genentech, Inc.
    Inventors: Yvonne M. Chen, Eugene Yu-Chuan Chiang, Jane Louise Grogan, Simon-Peter Williams, Matthew Lawrence Albert
  • CD8 BINDING AGENTS AND USES THEREOF
    Publication number: 20230192853
    Abstract: Provided are CD8 binding agents comprising a VHH domain that specifically binds human CD8. Also provided are nucleic acids encoding such CD8 binding agents, vectors comprising such nucleic acids, host cells comprising same, and methods of making such CD8 binding agents. Also provided are CD8 binding agents having the VHH domain conjugated to a detectable label. Provided are methods of using such CD8 binding agents to detect CD8+ T cells, monitor disease progress, and monitor treatment progress in a subject having cancer, autoimmune disease or condition, transplant rejection or graft-versus-host disease.
    Type: Application
    Filed: September 3, 2020
    Publication date: June 22, 2023
    Inventors: James Thomas KOERBER, Alejandra Beatrice Urpi URRUTIA, Simon-Peter WILLIAMS, Christopher Williamson DAVIES, Shravan Kumar SRIRAMAN, Herman Singh GILL, James Richard KIEFER, Jr.
  • ANTI-CD8 ANTIBODIES AND USES THEREOF
    Publication number: 20200172620
    Abstract: Provided are anti-CD8 antibodies that bind human CD8 and do not stimulate or inhibit the activation of CD8+ T cells. Also provided are nucleic acids encoding such anti-CD8 antibodies, vectors comprising such nucleic acids, host cells comprising same, and methods of making such anti-CD8 antibodies. Also provided are anti-CD8 antibodies conjugated to a detectable label. Provided are methods of using such anti-CD8 antibodies to detect CD8+ T cells in a subject, monitor disease progress in a subject having cancer, and monitor treatment progress in a subject having cancer.
    Type: Application
    Filed: February 11, 2020
    Publication date: June 4, 2020
    Applicant: Genentech, Inc.
    Inventors: Yvonne M. CHEN, Eugene Yu-Chuan CHIANG, Jane Louise GROGAN, Simon-Peter WILLIAMS, Matthew Lawrence ALBERT