Patents by Inventor Simon Quentyn John Rice

Simon Quentyn John Rice has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy
    Patent number: 7314742
    Abstract: The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.
    Type: Grant
    Filed: April 18, 2005
    Date of Patent: January 1, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Colin Houston MacPhee, David Graham Tew, Christopher Donald Southan, Deirdre Mary Bernadette Hickey, Israel Simon Gloger, Geoffrey Mark Prouse Lawrence, Simon Quentyn John Rice
  • Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy
    Patent number: 7045329
    Abstract: The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.
    Type: Grant
    Filed: August 3, 2001
    Date of Patent: May 16, 2006
    Assignee: SmithKline Beecham plc
    Inventors: Colin Houston MacPhee, David Graham Tew, Christopher Donald Southan, Deirdre Mary Bernadette Hickey, Israel Simon Gloger, Geoffrey Mark Prouse Lawrence, Simon Quentyn John Rice
  • Peptide-based gemini compounds
    Publication number: 20040043939
    Abstract: New peptide-based gemini compounds comprising two linked chains: 1
    Type: Application
    Filed: August 25, 2003
    Publication date: March 4, 2004
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Patrick Camilleri, Andreas Kremer, Simon Quentyn John Rice
  • Peptide-based gemini compounds
    Patent number: 6693167
    Abstract: New peptide-based Gemini compounds comprising two linked chains (a) each having: (1) a positively charged hydrophilic head, Q1 or Q2 formed from one or more amino acids and/or amines, (2) a central portion, P1 or P2, having a polypeptide backbone, and (3) a hydrophobic tail, R1 or R2, the central sections of each chain being linked together by bridge Y through residues in P1 and P2, are disclosed. Methods for their preparation and uses are also disclosed. Such uses include transfection of polynucleotides into cells in vivo.
    Type: Grant
    Filed: June 8, 2000
    Date of Patent: February 17, 2004
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Patrick Camilleri, Andreas Kremer, Simon Quentyn John Rice
  • Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy
    Publication number: 20020177209
    Abstract: The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.
    Type: Application
    Filed: August 3, 2001
    Publication date: November 28, 2002
    Applicant: SmithKline Beecham plc
    Inventors: Colin Houston MacPhee, David Graham Tew, Christopher Donald Southan, Deirdre Mary Bernadette Hickey, Israel Simon Gloger, Geoffrey Mark Prouse Lawrence, Simon Quentyn John Rice
  • Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy
    Patent number: 6177257
    Abstract: The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: January 23, 2001
    Assignee: SmithKline Beechman
    Inventors: Colin Houston Macphee, David Graham Tew, Christopher Donald Southan, Deirdre Mary Bernadette Hickey, Israel Simon Gloger, Geoffrey Mark Prouse Lawrence, Simon Quentyn John Rice
  • Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy
    Patent number: 5968818
    Abstract: The enzyme Lp-PLA.sub.2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA.sub.2, the use of an inhibitor of the enzyme Lp-PLA.sub.2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.
    Type: Grant
    Filed: November 14, 1995
    Date of Patent: October 19, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Israel Simon Gloger, Geoffrey Mark Prouse Lawrence, Simon Quentyn John Rice