Patents by Inventor Simon Restrepo

Simon Restrepo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220145387
    Abstract: Described herein is a method to create dendritic biocompatible polymers from pairs of complementary dendritic nucleic acid monomers in a controlled manner, using polymerization triggers. The dendritic monomers are constituted of nucleic acids and an organic polymer capable of self-assembly. A variety of additional improvements are described herein, including processes not requiring snap cooling, “wobble clamp” designs to confer a transitory measure of hairpin stability prior to branch migration, and multiple assemblies of amplifying systems. Depending on the context this technology could be used to reveal the presence of a large variety of analytes such as specific nucleic acid molecules, small molecules, proteins, and peptides.
    Type: Application
    Filed: December 20, 2019
    Publication date: May 12, 2022
    Applicant: University of Southern California
    Inventors: Scott E. Fraser, Simon Restrepo, Joseph P. Dunham
  • Publication number: 20200140921
    Abstract: Described herein is a method to create dendritic biocompatible polymers from pairs of complementary dendritic nucleic acid monomers in a controlled manner, using polymerization triggers. The dendritic monomers are constituted of nucleic acids and an organic polymer capable of self-assembly. Each polymer contains approximately 200 dendrites that can be used to attach labels and constitute a biologically compatible signal amplification technology. Depending on the context this technology could be used to reveal the presence of a large variety of analytes such as specific nucleic acid molecules, small molecules, proteins, and peptides.
    Type: Application
    Filed: February 28, 2018
    Publication date: May 7, 2020
    Applicant: University of Southern California
    Inventors: Scott E. Fraser, Simon Restrepo, Joseph P. Dunham