Abstract: A method for detecting a magnetic marker comprises generating a driving magnetic field comprising first and second frequencies and detecting a response magnetic field comprising first and second response components. The magnetic marker provides a non-linear response to the driving signal. A primary portion of the response components is generated by the magnetic marker, and secondary portion of the response components is generated by a secondary magnetic source. The method comprises determining a driving factor representing a ratio of the frequencies in the driving signal; determining a correction factor corresponding to the secondary portion of the second response component, based on the first response component and the driving factor; determining a detection signal corresponding to the primary portion of the second response component, based on the second response component and the determined correction factor; and generating an output signal based on a strength of the detection signal.

Abstract: This invention relates to the delivery of heterologous peptides or proteins such as therapeutic peptides, therapeutic proteins or antigens to mucosal sites using vesicles derived from the outer membrane of commensal bacteria, recombinant bacteria capable of producing such vesicles, and methods for the production of such vesicles. The invention further relates to an inducible expression system for use in recombinant bacteria.

Abstract: Disclosed are compounds, compositions and methods for treating disease, syndromes, conditions and disorders that are affected by the modulation of MALT-1. Such compounds are represented by Formula (I) and Formula (II), wherein the variables are defined herein.

Abstract: Systems, devices and methods for optimising and managing distributed energy storage and flexibility resources on a localised and group aggregation basis, particularly around the determination, analysis and predictive learning of local data patterns, scoring availability for flexibility and risk profiles, to inform the optimisation of energy supply and behind the meter storage resources and local clusters of co-located or close resources within a community, low voltage network, feeder, neighbourhood or building. Said optimisation to involve scheduled, reactive and active management of data sources and local clusters of resources, for a range of goals such as price, energy supply, renewable leverage, asset value, constraint or risk management.

Abstract: The present invention relates generally to systems, devices and methods for the efficient use of utilities, more particularly to the distribution and provision of electricity supply at appropriate voltages, monitoring and usage by end devices, and to facilitating consumers in changing their energy usage behaviour, and to adopt and easily install appropriate sustainable, energy efficient or renewable technologies. Said end devices typically including traditional electric, electronic and lighting appliances requiring AC or DC power provision or low voltage DC power via AC/DC converters.

Abstract: A system and method for locating magnetic material. In one embodiment the system includes a magnetic probe; a power module in electrical communication with the magnetic probe to supply current to the magnetic probe; a sense module in electrical communication with the magnetic probe to receive signals from the magnetic probe; and a computer in electrical communication with the power module and the sense module. The computer generates a waveform that controls the supply of current from the power module and receives a signal from the sense module that indicates the presence of magnetic material. The magnetic probe is constructed from a material having a coefficient of thermal expansion of substantially 10?6/° C. or less and a Young's modulus of substantially 50 GPa or greater. In one embodiment magnetic nanoparticles are injected into a breast and the lymph nodes collecting the particles are detected with the probe and deemed sentinel nodes.

Abstract: The present invention relates to an electroanalytical instrument for determining by amperometry (eg chronoamperometry) the presence or quantity (eg concentration) of an analyte in an aqueous sample, comprising a sealed housing, an elongate pivotal arm mounted on the sealed housing, wherein the elongate pivotal arm houses a potentiostat, and a pivotal forearm joined pivotally to the elongate pivotal arm, which is connectable to an electrochemical sensor. By flexing the pivotal forearm, the electrochemical sensor may be electrically connected to the potentiostat. By flexing the elongate pivotal arm, the electrochemical sensor is immersed in the aqueous sample in the sealed housing.

Abstract: The application relates to modular electronic apparatus (1) for distribution of RF communication signals. The apparatus comprises a chassis (2) arranged to removably receive plural modules (3), at least some of which are arranged to receive and process RF communication signals. A communication path (17) is provided for modules to communicate with each other and/or with the chassis. Plural modules received in the chassis. When a module is received in the chassis, it is arranged to broadcast a message over the communication path indicating its presence in the chassis and its type. At least one other module is arranged to adapt its behaviour in response to the message.

Abstract: A hemofilter system. In one embodiment, the hemofilter system includes a container having a first surface, a second surface, and one or more wall surfaces, the first surface, the second surface and the one or more wall surfaces defining a volume; an input port in fluid communication with the first surface; an output port in fluid communication with the second surface; a filter bed comprising a plurality of planar magnetic meshes stacked in close juxtaposition and positioned within the container volume and coplanar with the first and second surfaces; a first magnet positioned on a first surface of the container; a second magnet positioned on the second surface of the container; a first input conduit in fluid communication with the input port; and a first output conduit in fluid communication with the output port. In another embodiment, the hemofilter system includes a pump in the input conduit.

Abstract: A method, a computing system, and a computer program are disclosed. The method includes providing a first executable image file that includes first executable software associated with a graphical user interface application, executing the first executable image file as a first software container element that contains the first executable software and that is executable on one or more processors of a server that is remote from a computing device, transmitting display data associated with a graphical user interface to the computing device responsive to executing the first executable image file, and providing the graphical user interface on a display of the computing device.

Abstract: Methods, server computers, and computer programs are disclosed. An example method is disclosed that includes inputting, into an update module, a first version of a predefined modular image file and a delta encoded image file defining differences between the first version and a second, updated, version of the predefined modular image file, and outputting, from the update module, the second, updated, version of the predefined modular image file, where each version of the predefined modular image file includes at least one layer defining executable instructions and is one of a plurality of predefined modular image files that can be assembled as an executable image file for execution as a software container element.

Abstract: A system and method for locating magnetic material. In one embodiment the system includes a magnetic probe; a power module in electrical communication with the magnetic probe to supply current to the magnetic probe; a sense module in electrical communication with the magnetic probe to receive signals from the magnetic probe; and a computer in electrical communication with the power module and the sense module. The computer generates a waveform that controls the supply of current from the power module and receives a signal from the sense module that indicates the presence of magnetic material. The magnetic probe is constructed from a material having a coefficient of thermal expansion of substantially 10?6/° C. or less and a Young's modulus of substantially 50 GPa or greater. In one embodiment magnetic nanoparticles are injected into a breast and the lymph nodes collecting the particles are detected with the probe and deemed sentinel nodes.

Abstract: Disclosed are compounds, compositions and methods for treating disease, syndromes, conditions and disorders that are affected by the modulation of PKC-theta. Such compounds are represented by Formula I, wherein the variables are defined herein.

Abstract: Disclosed are compounds, compositions and methods for treating disease, syndromes, conditions and disorders that are affected by the modulation of PKC-theta. Such compounds are represented by Formula I, wherein the variables are defined herein.

Abstract: A track system of a vehicle can be monitored (e.g., during operation of the vehicle) to obtain information about the track system which can be used for various purposes, such as, for example, to convey the information about the track system to a user (e.g., an operator of the vehicle) and/or to control the vehicle, for instance, by controlling a speed of the vehicle depending on a state (e.g., a temperature and/or one or more other physical characteristics) of the track system. This may be useful, for example, to gain knowledge about a track of the track system, to help prevent rapid wear or other deterioration of the track of the track system (e.g., blowout), and/or to adapt how fast or slow the vehicle moves in order to protect the track of the track system while permitting the speed of the vehicle to be greater over short periods (e.g., when travelling on or crossing roads or other particular areas).

Abstract: A hemofilter system. In one embodiment, the hemofilter system includes a container having a first surface, a second surface, and one or more wall surfaces, the first surface, the second surface and the one or more wall surfaces defining a volume; an input port in fluid communication with the first surface; an output port in fluid communication with the second surface; a filter bed comprising a plurality of planar magnetic meshes stacked in close juxtaposition and positioned within the container volume and coplanar with the first and second surfaces; a first magnet positioned on a first surface of the container; a second magnet positioned on the second surface of the container; a first input conduit in fluid communication with the input port; and a first output conduit in fluid communication with the output port. In another embodiment, the hemofilter system includes a pump in the input conduit.

Abstract: The present invention relates generally to systems, devices and methods for the efficient use of utilities, more particularly to the distribution and provision of electricity supply at appropriate voltages, monitoring and usage by end devices, and to facilitating consumers in changing their energy usage behaviour, and to adopt and easily install appropriate sustainable, energy efficient or renewable technologies. Said end devices typically including traditional electric, electronic and lighting appliances requiring AC or DC power provision or low voltage DC power via AC/DC converters.

Abstract: A spectrophotometric instrument (1) for the quantitative measurement of an optical property of an analyte in a sample cell (4). The spectrophotometric instrument (1) comprises an instrument housing (2a, 2b) for a source of electromagnetic radiation and a detector; an optical pot (3) for accommodating the sample cell (4) having a flexible restraining cradle (6).

Abstract: The application relates to modular electronic apparatus (1) for distribution of RF communication signals. The apparatus comprises a chassis (2) arranged to removably receive plural modules (3), at least some of which are arranged to receive and process RF communication signals. A communication path (17) is provided for modules to communicate with each other and/or with the chassis. Plural modules received in the chassis. When a module is received in the chassis, it is arranged to broadcast a message over the communication path indicating its presence in the chassis and its type. At least one other module is arranged to adapt its behaviour in response to the message.

Abstract: A track for traction of a vehicle, such as an agricultural vehicle, an industrial vehicle (e.g., a construction vehicle), a military vehicle, or another off-road vehicle, is provided. The track comprises a ground-engaging outer surface for engaging the ground and a plurality of traction projections projecting from the ground-engaging outer surface and distributed in a longitudinal direction of the track. The traction projections may be designed to enhance their resistance to deterioration during use. For example, a blowout resistance of each traction projection may be enhanced to prevent or at least reduce a potential for blowout of the traction projection under repeated loads which may induce heat buildup within it. Also, a wear resistance of the traction projection may be enhanced such that the traction projection wears less rapidly. A system for protecting a track against potential occurrence of blowout is also provided.