Abstract: A nebulizer device for administering aerosol cannabinoid mixtures to a user includes a mouthpiece, a first reservoir, a second reservoir, and a nebulizer device. The nebulizer module is configured to receive a first dosage of the first liquid from the first reservoir and a second dosage of a second liquid from the second reservoir. The nebulizer module is also configured to transform the first liquid into an inhalant and the second liquid into an aerosol that are provided to the user through the mouthpiece. The device further includes a dosage module configured to independently control the delivery of the first liquid and the second liquid to the nebulizer module to set a ratio between the first dosage of the first liquid and the second dosage of the second liquid. The dosage module thereby controls a composition of an aerosol cannabinoid mixture administered to the user.

Abstract: A method for dispensing opioids using a dispensing container in an anti-addiction pain-modulating regimen includes generating a dosage scheme for dispensing an opioid compound using the dispensing container including a controller programmable according to the dosage scheme and locked compartments storing the opioid compound. The dosage scheme includes a first dosage scheme for an opioid compound and a first dosage scheme for a cannabinoid compound to be administered to the patient concurrently over a period of time. The method includes sending the dosage scheme for operating the dispensing container. The controller stores one or more authentication programs and is programmed to authenticate the patient using the one or more authentication programs, and in response to authenticating the patient, unlock one or more of the compartments to allow the patient to access to a dosage of the opioid compound held in the one or more compartments according to the dosage scheme.

Abstract: Systems and methods for generating transient object references are provided. The systems and methods perform operations including establishing a session between a first entity and a second entity. The operations include identifying an object that the first entity is authorized to access according to a first set of access privileges. The operations include generating a reference associated with the object. The operations include temporarily authorizing the second entity to access the object using the reference according to a second set of access privileges, the second set of access privileges being derived from the first set of access privileges.

Abstract: The present disclosure provides a pharmaceutical composition for multi-stage release of psychoactive substances including cannabinoids. The pharmaceutical composition comprises two or more staged compositions having different release profiles or different release time such that the one or more active agents in each of the two or more staged compositions are released into the subject's blood stream at different time points.

Abstract: A method of making a product from grass that includes carrying out steps A to D in order, where: Step A is cutting the grass to a length of between 35 mm to 150 mm resulting in cut grass with at least 90% leaf and little to no dead plant material; Step B is drying of the cut grass to produce dry grass; Step C is collecting and transferring the dry grass to at least one first container, removing excess air and then sealing the at least one first container; and Step D is aging the dry grass in the at least one first containers in a cool dark place for a primary period of time to produce a dry product.

Abstract: A method for reducing opioids in a pain-modulating regimen of a patient includes generating a dosage scheme for the patient based on parameters associated with the patient's health condition. The dosage scheme includes a first dosage scheme for an opioid compound and a first dosage scheme for a cannabinoid compound to be administered to the patient concurrently. The first dosage scheme for the opioid compound includes a first plurality of dosages with a decreasing amount of an active ingredient in the opioid compound over a period of time. The method also includes determining an addiction risk score for the patient based on the dosage scheme and determining whether to adjust the dosage scheme based on the addiction risk score for the patient. In response to determining to adjust the dosage scheme, the method includes generating an adjusted dosage scheme based on the addiction risk score indicators.

Abstract: The present disclosure is generally related to beverage containers, including cannabinoid and/or alkaloid-infused beverage containers, and associated devices, systems, and methods. In at least some embodiments, a beverage container can include one or more container walls forming the sides and/or bottom of the container, a conditioning component configured to releasably contain an active ingredient and to release at least a portion of the active ingredient into the container, and a lid which may be sealably attached to the container wall to create a sealed container. When a liquid is inserted into the beverage container and the lid is sealed to the container wall, the active ingredient can be held separate from the liquid by the conditioning component unless or until the conditioning component is activated/actuated to cause the active ingredient to mix with the liquid and create a beverage infused with the active ingredient.

Abstract: A nebulizer device for administering aerosol cannabinoid mixtures to a user includes a mouthpiece, a first reservoir, a second reservoir, and a nebulizer device. The nebulizer module is configured to receive a first dosage of the first liquid from the first reservoir and a second dosage of a second liquid from the second reservoir. The nebulizer module is also configured to transform the first liquid into an inhalant and the second liquid into an aerosol that are provided to the user through the mouthpiece. The device further includes a dosage module configured to independently control the delivery of the first liquid and the second liquid to the nebulizer module to set a ratio between the first dosage of the first liquid and the second dosage of the second liquid. The dosage module thereby controls a composition of an aerosol cannabinoid mixture administered to the user.

Abstract: A nebulizer device for administering aerosol cannabinoid mixtures to a user includes a mouthpiece, a first reservoir, a second reservoir, and a nebulizer device. The nebulizer module is configured to receive a first dosage of the first liquid from the first reservoir and a second dosage of a second liquid from the second reservoir. The nebulizer module is also configured to transform the first liquid into an inhalant and the second liquid into an aerosol that are provided to the user through the mouthpiece. The device further includes a dosage module configured to independently control the delivery of the first liquid and the second liquid to the nebulizer module to set a ratio between the first dosage of the first liquid and the second dosage of the second liquid. The dosage module thereby controls a composition of an aerosol cannabinoid mixture administered to the user.

Abstract: Described herein are systems and methods for automatically administering a psychoactive substance to a user based on detection of an event or condition during sleep. The systems and methods can be used to promote wellness in personal and research settings, and to facilitate brain-computer interface training, among other beneficial uses.

Abstract: The present disclosure is generally related to beverage containers, including cannabinoid and/or alkaloid-infused beverage containers, and associated devices, systems, and methods. In at least some embodiments, a beverage container can include one or more container walls forming the sides and/or bottom of the container, a conditioning component configured to releasably contain an active ingredient and to release at least a portion of the active ingredient into the container, and a lid which may be sealably attached to the container wall to create a sealed container. When a liquid is inserted into the beverage container and the lid is sealed to the container wall, the active ingredient can be held separate from the liquid by the conditioning component unless or until the conditioning component is activated/actuated to cause the active ingredient to mix with the liquid and create a beverage infused with the active ingredient.

Abstract: The present disclosure provides a pharmaceutical composition for multi-stage release of psychoactive substances including cannabinoids. The pharmaceutical composition comprises two or more staged compositions having different release profiles or different release time such that the one or more active agents in each of the two or more staged compositions are released into the subject's blood stream at different time points.

Abstract: A haemostat agent in the form of a multi-layer patch comprising at least first and second layers, wherein said first layer comprises a composition comprising fibrous ?-chitin (which may be sourced from a marine source such as squid pens) and one or more biocompatible polymer (for example, a polyethylene glycol (PEG) polymer or sodium polyphosphate (PolyP)), and said second layer comprises a film layer comprising fibrous ?-chitin. In one particular application, the haemostat agent is used for treating carotid artery injury associated with endonasal surgery.

Abstract: The disclosed subject matter relates to a method for determining phase offsets in a complex-valued image in Magnetic Resonance Imaging, including the steps of, immobilising an object and acquiring a first image thereof at a predetermined first echo time and a second image thereof at a predetermined second echo time, the first and second images being separated into first and second magnitude images and first and second phase images, respectively, wherein a ratio between said first echo time and said second echo time is chosen to be n:(n+1), n being a positive integer; generating, pixel by pixel, a phase evolution image; and subtracting, pixel by pixel, an n-fold of the phase evolution image from the first phase image to obtain a phase offset image containing said phase offsets.

Abstract: The disclosed subject matter relates to a method for determining phase offsets in a complex-valued image in Magnetic Resonance Imaging, including the steps of, immobilising an object and acquiring a first image thereof at a predetermined first echo time and a second image thereof at a predetermined second echo time, the first and second images being separated into first and second magnitude images and first and second phase images, respectively, wherein a ratio between said first echo time and said second echo time is chosen to be n:(n+1), n being a positive integer; generating, pixel by pixel, a phase evolution image; and subtracting, pixel by pixel, an n-fold of the phase evolution image from the first phase image to obtain a phase offset image containing said phase offsets.

Abstract: Convertible surgical tissue staplers and applications thereof, having small sizes and high suitability for introduction and delivery through small surgical incisions or cuts, natural orifices, or laparoscopic ports, followed by deployment to full operational configurations. Convertible surgical tissue stapler may be a linear tissue stapler such as endo cutter stapler. Linear tissue stapler includes: elongated body having longitudinal axis; and stapling head, including first and second members, at least one with rows of tissue fasteners. Convertible from delivery configuration, whereby members are consecutively arranged lengthwise, with overall diameter smaller than minimal inner diameter, to deployment configuration, whereby members are juxtapositionally arranged, with overall diameter equal to or greater than minimal inner diameter.

Abstract: Staplers and stapler heads for surgically fastening and cutting a bodily tissue or/and organ, including: a stapling jaw configured to include a first stapling jaw portion and a second stapling jaw portion separated from each other by a longitudinal channel. A blade having a sharp edge may be shiftable from a horizontal position to a vertical position so as to allow traveling thereof along the longitudinal channel. First stapling jaw portion may include a first row of tissue fasteners of a first staple size or/and type, and second stapling jaw portion may include a second row of tissue fasteners of a second staple size or/and type. Also described are methods for surgically fastening and cutting a bodily tissue or/and organ.

Abstract: The edge identification system receives a pair of images from which an in-between image is to be created. The edge identification system calculates two vector fields: one to warp the second image onto the first, and the other to warp the first image onto the second. The two vector fields are typically symmetric; however, the fields are not symmetric along the edge of an object (e.g., the foreground) that is moving differently than the layer behind it (e.g., the background). This type of movement creates occlusions in which an object that was visible in one image will not be visible in the other image and vice versa. The edge identification system uses these areas to automatically identify the edges of moving objects. Thus, the edge identification system can identify the edges of objects without requiring the user to provide a matte or other manual assistance.

Abstract: A four-corner motion system for precisely modeling local motion is provided. The four-corner motion system provides a motion estimation technique that uses a four-corner transform to describe planar motion. The four-corner motion system produces a motion field that describes the motion of each block in a reference frame at the four-corner level. Thus, the four-corner motion system provides more precise modeling of local motion.

Abstract: The present disclosure is directed, in part, to compounds and methods for imaging myocardial perfusion, comprising administering to a patient a contrast agent which comprises a compound that binds MC-1, and an imaging moiety, and scanning the patient using diagnostic imaging.