Abstract: The present invention relates to a binding molecule that specifically binds to two different epitopes of an antigen expressed on tumor cells, wherein the binding molecule comprises: (a) a first binding (poly)peptide that specifically binds to a first epitope of said antigen expressed on tumor cells, wherein said first binding (poly)peptide is a Fyn SH3-derived polypeptide; and (b) a second binding (poly)peptide that specifically binds to a second epitope of said antigen expressed on tumor cells. The present invention further relates to a nucleic acid molecule encoding the binding molecule of the invention, a vector comprising said nucleic acid molecule as well as a host cell or a non-human host transformed with said vector. The invention further relates to a method of producing a binding molecule of the invention as well as to pharmaceutical and diagnostic composition.

Abstract: The invention relates to lithium perfluoroalkylfluorosilicates, to their preparation, and to their use as conductive salts in electrochemical cells, more particularly in lithium batteries, lithium ion batteries or lithium ion capacitors, and also to electrolytes or electrochemical cells comprising these lithium perfluoroalkylfluorosilicates.

Abstract: Double clutch for coupling a drive shaft of a motor to a transmission shaft of a transmission in a vehicle having a first friction clutch for frictionally clamping a first clutch disc couplable to the transmission shaft between a first pressure plate and a first counter-plate, the first pressure plate displaceable in an axial direction to close the first friction clutch, a second friction clutch for frictionally clamping a second clutch disc couplable to an accessory power take-off between a second pressure plate and a second counter-plate, the second pressure plate displaceable in the axial direction to close the second friction clutch, a first actuating element configured to displace the first pressure plate, and, a second actuating element configured to engage a pressure ring connected to the second pressure plate to displace the second pressure plate, wherein the second actuating element is pre-loaded by at least one wire load ring.

Abstract: A dual clutch for coupling an engine drive shaft with a transmission shaft and/or an auxiliary power take-off. A first friction clutch presses a first clutch plate that is couplable with the transmission shaft between a first contact plate, displaceable in an axial direction to engage the first friction clutch and a first counter plate. A second friction clutch presses a second clutch plate that is couplable with the auxiliary power take-off between a second contact plate, displaceable in the axial direction to engage the second friction clutch and a second counter plate. First and second actuating elements move the first and second contact plates; respectively. The second contact plate is connected to a thrust ring connected to the second actuating element to transfer displacing movement.

Abstract: The present invention relates to new IL-17 inhibiting polypeptides, corresponding fusion proteins, compositions and medical uses thereof.

Abstract: The present invention relates to new IL-17 inhibiting polypeptides, corresponding fusion proteins, compositions and medical uses thereof.

Abstract: Double clutch for coupling a drive shaft of a motor to a transmission shaft of a transmission in a vehicle having a first friction clutch for frictionally clamping a first clutch disc couplable to the transmission shaft between a first pressure plate and a first counter-plate, the first pressure plate displaceable in an axial direction to close the first friction clutch, a second friction clutch for frictionally clamping a second clutch disc couplable to an accessory power take-off between a second pressure plate and a second counter-plate, the second pressure plate displaceable in the axial direction to close the second friction clutch, a first actuating element configured to displace the first pressure plate, and, a second actuating element configured to engage a pressure ring connected to the second pressure plate to displace the second pressure plate, wherein the second actuating element is pre-loaded by at least one wire load ring.

Abstract: A dual clutch for coupling an engine drive shaft with a transmission shaft and/or an auxiliary power take-off. A first friction clutch presses a first clutch plate that is couplable with the transmission shaft between a first contact plate, displaceable in an axial direction to engage the first friction clutch and a first counter plate. A second friction clutch presses a second clutch plate that is couplable with the auxiliary power take-off between a second contact plate, displaceable in the axial direction to engage the second friction clutch and a second counter plate. First and second actuating elements move the first and second contact plates; respectively. The second contact plate is connected to a thrust ring connected to the second actuating element to transfer displacing movement.

Abstract: The invention relates to lithium perfluoroalkylfluorosilicates, to their preparation, and to their use as conductive salts in electrochemical cells, more particularly in lithium batteries, lithium ion batteries or lithium ion capacitors, and also to electrolytes or electrochemical cells comprising these lithium perfluoroalkylfluorosilicates.

Abstract: The present invention relates to new IL-17 inhibiting polypeptides, corresponding fusion proteins, compositions and medical uses thereof.