Abstract: An ejector device is provided for food portions, and in particular for sausages. A food portion in a conveying area between two conveyor belts is engaged in a conveying mode and can be conveyed in the conveying direction. It is proposed that the ejector device has at least one adjustment mechanism for ejecting a food portion in an ejection area, which is so designed that the distance of the conveyor belts from each other in the conveying area can be partially varied. A method of ejecting food portions is also provided, in which it is proposed that the food portions be taken out of engagement with the conveyor belts as described above.

Abstract: An ejector device is provided for food portions, and in particular for sausages. A food portion in a conveying area between two conveyor belts is engaged in a conveying mode and can be conveyed in the conveying direction. It is proposed that the ejector device has at least one adjustment mechanism for ejecting a food portion in an ejection area, which is so designed that the distance of the conveyor belts from each other in the conveying area can be partially varied. A method of ejecting food portions is also provided, in which it is proposed that the food portions be taken out of engagement with the conveyor belts as described above.

Abstract: The invention relates to an apparatus and an in-situ method for detecting cellular DNA damage. The invention is particularly suited for use in Comet assays and for automation of such assays. The apparatus comprises a multiwell plate, the plate comprising an array of wells held in fixed relationship with each other and each well having an axis, side walls, and a base and wherein the well is provided with electrode pairs disposed therein; and wherein there is provided means for parallel connection of the electrode pairs to an external voltage supply.

Abstract: The present invention relates to polypeptide and nucleic acids constructs which are useful for determining the cell cycle status of a mammalian cell. Host cells transfected with these nucleic acid constructs can be used to determine the effects that test agents have upon the mammalian cell cycle.

Abstract: The present invention relates to non-destructive and dynamic means for determining the cell cycle position of living cells. The invention provides stable cell lines which can be used to determine the cell cycle position, together with methods for measuring the effect of a test agent on the cell cycle position.

Abstract: The present invention relates to polypeptide and nucleic acids constructs which are useful for determining the cell cycle status of a mammalian cell. Host cells transfected with these nucleic acid constructs can be used to determine the effects that test agents have upon the mammalian cell cycle.

Abstract: The present invention relates to polypeptide and nucleic acids constructs which are useful for determining the cell cycle status of a mammalian cell. Host cells transfected with these nucleic acid constructs can be used to determine the effects that test agents have upon the mammalian cell cycle.

Abstract: The present invention relates to polypeptide and nucleic acids constructs which are useful for determining the cell cycle status of a mammalian cell. Host cells transfected with these nucleic acid constructs can be used to determine the effects that test agents have upon the mammalian cell cycle.

Abstract: The present invention relates to non-destructive and dynamic means for determining the cell cycle position of living cells. The invention provides stable cell lines which can be used to determine the cell cycle position, together with methods for measuring the effect of a test agent on the cell cycle position.

Abstract: The present invention relates to nucleic acid reporter constructs and host cells transfected with said constructs. The invention also relates to methods which are useful for determining the cell cycle status of a mammalian cell and for determining the effect of a test agent on the cell cycle position of a mammalian cell.

Abstract: An in vitro method for characterising the activity and/or the function of a test agent on signalling pathways and/or cellular processes within a host cell is disclosed which is conducted on living cells in a none-destructive manner. The method of the invention may be used with an imaging system and a computerised data processing device.

Abstract: An automated method for measuring the development of a biofilm, containing one or more fluorescent moieties, on a plurality of surfaces using a confocal imaging system including: a) a radiation source system for forming a beam of electromagnetic radiation including one or more wavelengths; b) an optical system for directing and focusing said beam onto one or more planes of the object; c) a detection system for detecting electromagnetic radiation emitted from the object and producing image data; and d) a scanning system for scanning the object in a plurality of planes with the electromagnetic radiation, the method comprising the steps of: i) growing said biofilm on said plurality of surfaces; ii) detecting the presence of said one or more fluorescent moieties within the biofilm by scanning the biofilm with electromagnetic radiation in a plurality of planes and collecting fluorescent emissions to produce a plurality of images; and iii) analysing said images by means of a data processing system under the control

Abstract: The present invention provides novel engineered derivatives of green fluorescent protein (GFP) which have an amino acid sequence which is modified by amino acid substitution compared with the amino acid sequence of wild type Green Fluorescent Protein. The modified GFPs exhibit enhanced fluorescence relative to wtGFP when expressed in non-homologous cells at temperatures above 30° C., and when excited at about 490 nm compared to the parent proteins, i.e. wtGFP. An example of a preferred protein is F64L-S175G-E222G-GFP. The modified GFPs provide a means for detecting GFP reporters in mammalian cells at lower levels of expression and/or increased sensitivity relative to wtGFP. This greatly improves the usefulness of fluorescent proteins in studying cellular functions in living cells.