Abstract: Disclosed embodiments concern novel interleukin receptor associated kinases (IRAK) inhibitors and compositions comprising such inhibitors. Also disclosed are methods of making and using the compounds and compositions. The disclosed compounds and/or compositions may be used to treat or prevent an IRAK-associated disease or condition.

Abstract: A magnetic debris level measuring device for a magnetic filter is disclosed. The magnetic debris level measuring device includes a magnetometer and a temperature sensor. The temperature measured by the temperature sensor is used to calculate a corrected magnetometer reading, which in turn can be used to determine the amount of captured magnetic debris held within the filter. The device has a stored threshold for the corrected magnetometer reading, and when the corrected magnetometer reading crosses the stored threshold a notification is issued that the filter is full. If it is detected that debris continues to be captured after the ‘full’ notification has been issued, the stored threshold will be updated accordingly.

Abstract: A fluid release system for a fuel cell comprises a conduit for communicating water from the fuel cell to one or more outlets; and, a water discharge arrangement arranged to selectively release water from the one or more outlets, wherein the water discharge arrangement is arranged to controllably open the one or more outlets to selectively release water from the one or more outlets.

Abstract: A nozzle for an electrochemical machining device. The nozzle defining a body with first and second releasably attachable body portions forming an electrolyte cavity therebetween, when the first and second body portions are attached. The body includes an inlet port upstream of the cavity, and an outlet port for dispensing a jet of electrolyte towards a surface of a workpiece, in use, where a flow path is defined from the inlet port through the cavity to the outlet port.

Abstract: Various embodiments provide for determining redundant logic in a circuit design based on one or more enable conditions of clock gates, which can be part of electronic design automation (EDA). In particular, some embodiments use one or more enable conditions (of the clock gates) with a satisfiability solver to determine redundant logic coupled to clock circuit elements gated by the clock gates.

Abstract: The invention relates to an interactive headphone system for storing and playing audio content comprising an NFC tag with an RFID code that contains a distinctive identification of the NFC tag, and headphones that comprise a memory that stores one or more audio files, where each of the one or more audio files is associated with a distinctive identification, where the one or more audio files are locked so that access is possible only with an RFID code containing a distinctive identification corresponding to the distinctive identification of a respective audio file, and an NFC reader, where, when the NFC tag having a distinctive identification corresponding to the distinctive identification of a respective audio file is brought into the immediate vicinity of the NFC reader, the headphones are configured to: process the RFID code containing the distinctive identification of the NFC tag; correlate the distinctive identification of the NFC tag with the distinctive identification of the audio file stored on the mem

Abstract: An article of footwear includes an upper having a fastening mechanism, a sole, and a frame having an exterior surface and an interior surface. The sole includes a midsole structure and an outsole structure. The interior surface of the frame is adjacent portions of the midsole structure, the outsole structure, and the upper. The frame further has a lattice-work structure formed by a plurality of apertures extending through the interior and exterior surfaces of the frame such that at least some of the portions of the midsole structure, the outsole structure, and the upper adjacent the interior surface of the frame are exposed through the plurality of apertures. The fastening mechanism includes a fastening member extending through at least one aperture of the plurality of apertures of the frame.

Abstract: The present disclosure relates to a motor drive system comprising: a fuel cell; a motor, electrically connected to the fuel cell; and, a cryogenic system arranged to contain a cryogen, wherein the fuel cell is arranged to output current to the motor, and wherein the cryogenic system is arranged to communicate a cryogen from the cryogenic system to the fuel cell.

Abstract: Various embodiments provide for determining clock gates for decloning based on simulation and a satisfiability solver, which can be part of electronic design automation (EDA). In particular, some embodiments use a simulation process to quickly determine whether enable signals associated with two clock gates are logically equivalent using a random input vector to a circuit design and, if logically equivalent by the simulation process, use a satisfiability solver to determine a variable assignment (e.g., at least one vector) such that the enable signals are found to be non-equivalent.

Abstract: A multi-source aircraft propulsion arrangement comprises a cryogenic propulsion source and a combustion propulsion source wherein the cryogenic propulsion source and the combustion propulsion source may be selectively and independently operated to generate propulsive force for an aircraft.

Abstract: A biofeedback rehabilitation display for gait training visible to the subject including a plurality of foot placement targets visible to the subject on the display and moving along the display at a speed proportional to the desired gait speed of the subject and in a direction along the display representative of the direction of locomotion of the subject; a pair of subject foot icons visible to the subject illustrating real-time foot positioning of the subject throughout the gait pattern of the subject, wherein the foot icons distinguish between stance phase and swing phase throughout the gait pattern of the subject; and at least one real-time proximity measurement visible to the subject for each stance phase providing the subject with an indication of the proximity of each stance phase of each foot with an intended foot placement target.

Abstract: An optically readable marker includes data to be extracted; and an identifier arranged to identify a location of the data to be extracted. The identifier includes a plurality of dots arranged in a set pattern, the dots being small compared to the size of the data to be extracted. The identifier may be used on a beverage container, and/or for augmented reality applications.

Abstract: A biofeedback rehabilitation display for gait training visible to the subject including a plurality of foot placement targets visible to the subject on the display and moving along the display at a speed proportional to the desired gait speed of the subject and in a direction along the display representative of the direction of locomotion of the subject; a pair of subject foot icons visible to the subject illustrating real-time foot positioning of the subject throughout the gait pattern of the subject, wherein the foot icons distinguish between stance phase and swing phase throughout the gait pattern of the subject; and at least one real-time proximity measurement visible to the subject for each stance phase providing the subject with an indication of the proximity of each stance phase of each foot with an intended foot placement target.

Abstract: Methods and kits for analysing a sample from a test subject. The methods involve determining the level of at least one compound selected from the group consisting of N-acetylglutamate, methionine, acetylcarnitine, indole-3-acetate, 2-oxoglutarate, anserine, aspartate and butyrate in the sample from the test subject; and comparing the level of the at least one compound determined to at least one control level, wherein the levels of the at least one compound are indicative of whether the subject has hepatic cancer.

Abstract: Systems and methods of electronic document handling permit organizations to comply with legal or regulatory requirements, electronic discovery and legal hold requirements, and/or other business requirements. The systems described provide a unified approach to data management that enables compliance, legal and IT personnel to focus efforts on, e.g., a single data repository. The systems permit users to define and utilize information governance policies that help automate and systematize different compliance tasks. In some examples, organizations may push data in any third-party data format to the systems described herein. The systems may permit compliance or IT personnel to detect when a legally sensitive production file has been changed or deleted. The systems may also provide a unified dashboard user interface. From a dashboard interface, users may perform searches, participate in collaborative data management workflows, obtain data management reports, and adjust policies.

Abstract: A resonant radiofrequency (RF) detector assembly comprising a substrate, a coil formed on a front surface of the substrate, and two capacitors, each capacitor having a front plate which is formed on the front surface of the substrate and a rear plate formed on a rear surface of the substrate, the two front plates each being electrically connected to a different end of the coil, and the two rear plates being electrically connected to each other.

Abstract: Systems and methods of electronic document handling permit organizations to comply with legal or regulatory requirements, electronic discovery and legal hold requirements, and/or other business requirements. The systems described provide a unified approach to data management that enables compliance, legal and IT personnel to focus efforts on, e.g., a single data repository. The systems permit users to define and utilize information governance policies that help automate and systematize different compliance tasks. In some examples, organizations may push data in any third-party data format to the systems described herein. The systems may permit compliance or IT personnel to detect when a legally sensitive production file has been changed or deleted. The systems may also provide a unified dashboard user interface. From a dashboard interface, users may perform searches, participate in collaborative data management workflows, obtain data management reports, and adjust policies.

Abstract: A power adaptor for a computer discovers the power environment when it is plugged into a socket and sends a signal to the computer along the power line indicating the environment, so that the computer can configure operations accordingly.