Patents by Inventor Simon Tierens

Simon Tierens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of imaging a cardiovascular disease with an anti-macrophage mannose receptor immunoglobulin single variable domain
    Patent number: 9617339
    Abstract: The disclosure relates to the field of cardiovascular diseases. In particular, immunoglobulin single variable domains directed against macrophage mannose receptor (MMR) are provided that can be used in the diagnosis, prognosis and/or monitoring of cardiovascular diseases or as therapeutics. Also, the anti-macrophage mannose receptor (MMR) immunoglobulin single variable domains of the disclosure are useful at different stages of cardiovascular diseases, including post-infarction cardiovascular events. Further, the anti-macrophage mannose receptor (MMR) immunoglobulin single variable domains of the disclosure are particularly useful for the in vivo targeting and/or imaging of vulnerable atherosclerotic plaques.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: April 11, 2017
    Assignees: VIB VZW, Vrije Universiteit Brussel
    Inventors: Patrick De Baetselier, Geert Raes, Steve Schoonooghe, Jens De Vos, Tony Lahoutte, Nick Devoogdt, Sophie Hernot, Gezim Bala, Simon Tierens
  • ANTI-MACROPHAGE MANNOSE RECEPTOR SINGLE VARIABLE DOMAINS FOR USE IN CARDIOVASCULAR DISEASES
    Publication number: 20160024213
    Abstract: The disclosure relates to the field of cardiovascular diseases. In particular, immunoglobulin single variable domains directed against macrophage mannose receptor (MMR) are provided that can be used in the diagnosis, prognosis and/or monitoring of cardiovascular diseases or as therapeutics. Also, the anti-macrophage mannose receptor (MMR) immunoglobulin single variable domains of the disclosure are useful at different stages of cardiovascular diseases, including post-infarction cardiovascular events. Further, the anti-macrophage mannose receptor (MMR) immunoglobulin single variable domains of the disclosure are particularly useful for the in vivo targeting and/or imaging of vulnerable atherosclerotic plaques.
    Type: Application
    Filed: March 17, 2014
    Publication date: January 28, 2016
    Inventors: Patrick De Baetselier, Geert Raes, Steve Schoonooghe, Jens De Vos, Tony Lahoutte, Nick Devoogdt, Sophie Hernot, Gezim Bala, Simon Tierens