Abstract: The present invention relates to inorganic salts of nicotinic acid mononucleotides and compositions of Formula I, useful in the treatment of disorders and diseases associated with deficiencies in NAD+: wherein A, M1, M2, k, R1, R2, and R3 are as described herein.

Abstract: The present invention is directed to PVP-I formulations having enhanced virucidal activity. The formulations are intended for topical administration for treatment and/or decreased risk of microbial infections in subjects. The formulations include PVP-I and other ingredients selected to enhance the virucidal activity of the formulation over PVP-I alone.

Abstract: A computer-implemented system and method for building context models in real time is provided. A contextual situation of a user is determined and compared with models each associated with actions that represent a situation. A determination is made that none of the models represents the situation of the user. A similarity value is determined for each of at least a portion of the models with the situation of the user. A threshold is applied to the similarity values. All models associated with a similarity value that satisfies the threshold are selected. The selected models are merged into a new model for the situation by utilizing a weight associated with each of the selected models to identify those actions in the selected models for inclusion in the new model.

Abstract: A computer-implemented system and method for building context models in real time is provided. A database of models for a user is maintained. Each model represents a contextual situation and includes one or more actions. Contextual data is collected for the user and a contextual situation is identified for that user based on the collected contextual information. Models related to the identified situation are selected and merged. One or more actions from the merged model are then selected.

Abstract: A computer-implemented system and method for predicting activity outcome is provided. A set of outcome models is maintained. Contextual data of a user is collected via one or more computing devices associated with the user. An activity being performed by the user is determined based on the contextual data. The activity is compared to a set of outcome models. A predication is made that the activity will not be successfully completed by the user without assistance based on the comparison. The user is provided with one or more tasks for completion of the activity.

Abstract: The present invention relates to amino acid salts of nicotinic acid mononucleotides and nicotinamide mononucleotides and compositions thereof of Formula I, useful in the treatment of disorders and diseases associated with deficiencies in NAD+: wherein A, M1, M2, R1, R2, and R3 are as described herein.

Abstract: The present invention relates to amino acid salts of nicotinic acid and nicotinamide and compositions thereof of Formula I, useful in the treatment of disorders and diseases associated with deficiencies in NAD+: wherein A, L, M1, M2, R1, R2, and R3 are as described herein.

Abstract: A computer-implemented system and method for predicting activity outcome based on user attention is provided. Sensor data is collected for a user, and an activity performed by a user is identified based on the sensor data. Features of the user are collected while performing the activity and a subject of focus of the user is determined based on the collected features. An outcome of the activity performed by the user is predicted based on the features and the determined subject of focus.

Abstract: The present invention relates to inorganic salts of nicotinamide mononucleotides and compositions of Formula I, useful in the treatment of disorders and diseases associated with deficiencies in NAD+: wherein A, M, k, R1 and R2 are as described herein.

Abstract: The present invention relates to amino acid salts of nicotinic acid ribosides and compositions thereof of Formula I, useful in the treatment of disorders and diseases associated with deficiencies in NAD+: wherein M1, R1, R2, and R3 are as described herein.

Abstract: A computer-implemented system and method for providing contextually relevant task recommendations to qualified users is provided. Contextual data for a user is collected via one more sensors associated with the user. An activity being performed by the user is determined based on the contextual data. The activity is compared with a profile of the user and a determination that the user is qualified to perform the activity is verified. The activity is monitored. At least one recommendation for performance of a step is identified during the activity and transmitted to at least one recipient including the user or another user.

Abstract: The present invention relates to inorganic salts of nicotinic acid mononucleotides and compositions of Formula I, useful in the treatment of disorders and diseases associated with deficiencies in NAD+: wherein A, M1, M2, k, R1, R2, and R3 are as described herein.

Abstract: A computer-implemented system and method for providing contextually relevant task recommendations to qualified users is provided. Sensor data is collected for a user. The user's location is determined and subsequently, an activity of the user is determined based on the sensor data and the location. Two or more recommendable items are scored based on the activity and one or more of the recommendable items with the highest scores are selected. Finally, one or more recipients qualified to perform each of the recommendable items are identified.

Abstract: The present invention relates to inorganic salts of nicotinic acid mononucleotides and compositions of Formula I, useful in the treatment of disorders and diseases associated with deficiencies in NAD+: wherein A, M1, M2, k, R1, R2, and R3 are as described herein.

Abstract: The present invention relates to inorganic salts of nicotinic acid mononucleotides and compositions of Formula I, useful in the treatment of disorders and diseases associated with deficiencies in NAD+: wherein A, M1, M2, k, R1, R2, and R3 are as described herein.

Abstract: A computer-implemented system and method for dynamic travel coordination is provided. A common destination is designated for a group of travelers for arrival at a common time. A mode of travel and a set of travel criteria are designated for each traveler. The travel criteria are determined for at least one of the travelers by receiving travel criteria for the at least one traveler from another traveler and receiving from the at least one traveler modifications to the received travel criteria. An initial route to the common destination at the common arrival time is created for each of the travelers based on the travel mode and travel criteria for that traveler. The initial route of one or more of the travelers is revised based on at least one of that traveler's designated travel criteria, a progress of one or more of the travelers, and travel conditions of the initial route.

Abstract: A computer-implemented system and method for dynamic travel coordination is provided. A common destination is designated for a group of travelers for arrival at a common time. A mode of travel and a set of travel criteria are designated for each traveler. The travel criteria are determined for at least one of the travelers by receiving travel criteria for the at least one traveler from another traveler and receiving from the at least one traveler modifications to the received travel criteria. An initial route to the common destination at the common arrival time is created for each of the travelers based on the travel mode and travel criteria for that traveler. The initial route of one or more of the travelers is revised based on at least one of that traveler's designated travel criteria, a progress of one or more of the travelers, and travel conditions of the initial route.

Abstract: A computer-implemented system and method for dynamic travel coordination is provided. A common destination is designated for a group of travelers for arrival at a common time. A mode of travel and a set of travel criteria are designated for each traveler. The travel criteria are determined for at least one of the travelers by receiving travel criteria for the at least one traveler from another traveler and receiving from the at least one traveler modifications to the received travel criteria. An initial route to the common destination at the common arrival time is created for each of the travelers based on the travel mode and travel criteria for that traveler. The initial route of one or more of the travelers is revised based on at least one of that traveler's designated travel criteria, a progress of one or more of the travelers, and travel conditions of the initial route.

Abstract: A computer-implemented system and method for dynamically generating documents based on user context is provided. Blocks of document content are maintained and contextual data of a user is collected. The contextual data is compared to a set of stored models for the user and one or more models related to the user's context are identified. One or more content blocks are selected based on the identified models and a document is generated for the user by compiling the selected content blocks.

Abstract: A computer-implemented system and method for building context models in real time is provided. A database of models for a user is maintained. Each model represents a contextual situation and includes one or more actions. Contextual data is collected for the user and a contextual situation is identified for that user based on the collected contextual information. Models related to the identified situation are selected and merged. One or more actions from the merged model are then selected.