Patents by Inventor Simon Wadle

Simon Wadle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TWO-PART MEDIATOR PROBE
    Publication number: 20230407376
    Abstract: The present invention concerns a mediator probe for the detection of at least one target molecule comprising at least two oligonucleotides. A first oligonucleotide of the mediator probe according to the invention comprises a probe region and a mediator binding region, wherein the probe region has an affinity to a target molecule and/or template molecule, and the mediator binding region has an affinity to at least one mediator. At least one further oligonucleotide of the mediator probe is a mediator which is bound to the first oligonucleotide of the mediator probe via the mediator binding region and has an affinity for at least one detection molecule, wherein the mediator triggers a detectable signal by interaction with the detection molecule after release from the first oligonucleotide of the mediator probe.
    Type: Application
    Filed: February 24, 2023
    Publication date: December 21, 2023
    Applicants: Albert-Ludwigs-Universitat Freiburg, Hahn-Schickard-Gesellschaft Fur Angewandte Forschung E.V.
    Inventors: Martin Trotter, Simon Wadle, Felix Von Stetten, Lisa Becherer
  • Bifunctional oligonucleotide probe for universal real time multianalyte detection
    Patent number: 11293053
    Abstract: The invention relates to a mediator probe comprising a probe region and a mediator region. Furthermore, the invention relates to a system comprising a mediator probe and a detection molecule, use of that system and a method for detection of at least one target molecule.
    Type: Grant
    Filed: November 12, 2012
    Date of Patent: April 5, 2022
    Assignee: ALBERT-LUDWIGS-UNIVERSITAET FREIBURG
    Inventors: Guenter Roth, Bernd Faltin, Felix Von Stetten, Simon Wadle
  • TWO-PART MEDIATOR PROBE
    Publication number: 20190376126
    Abstract: The present invention concerns a mediator probe for the detection of at least one target molecule comprising at least two oligonucleotides. A first oligonucleotide of the mediator probe according to the invention comprises a probe region and a mediator binding region, wherein the probe region has an affinity to a target molecule and/or template molecule, and the mediator binding region has an affinity to at least one mediator. At least one further oligonucleotide of the mediator probe is a mediator which is bound to the first oligonucleotide of the mediator probe via the mediator binding region and has an affinity for at least one detection molecule, wherein the mediator triggers a detectable signal by interaction with the detection molecule after release from the first oligonucleotide of the mediator probe.
    Type: Application
    Filed: December 15, 2017
    Publication date: December 12, 2019
    Inventors: Martin TROTTER, Simon WADLE, Felix VON STETTEN, Lisa BECHERER
  • BIFUNCTIONAL OLIGONUCLEOTIDE PROBE FOR UNIVERSAL REAL TIME MULTIANALYTE DETECTION
    Publication number: 20140315747
    Abstract: The invention relates to a mediator probe comprising a probe region and a mediator region. Furthermore, the invention relates to a system comprising a mediator probe and a detection molecule, use of that system and a method for detection of at least one target molecule.
    Type: Application
    Filed: November 12, 2012
    Publication date: October 23, 2014
    Inventors: Guenter Roth, Bernd Faltin, Felix Von Stetten, Simon Wadle