Patents by Inventor Simon Wain-Hobson

Simon Wain-Hobson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic kits and methods for detecting antibodies to LAV viruses
    Patent number: 5747242
    Abstract: A variant of a LAV virus, designated LAV.sub.ELI and cable of causing AIDS. The cDNA and antigens of the LAV.sub.ELI virus can be used for the diagnosis of AIDS an pre-AIDS.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: May 5, 1998
    Assignee: Institut Pasteur
    Inventors: Marc Alizon, Pierre Sonigo, Simon Wain-Hobson, Luc Montagnier
  • NEF peptide encoded by human immunodefiency virus type 1 (HIV-1)
    Patent number: 5705612
    Abstract: The complete nucleotide sequence of a proviral molecular clone of the lymphadenopathy-associated virus, LAV, was ascertained. Recombinant phage clones were isolated from a genomic library of LAV-infected human T-lymphocyte DNA. The insert of recombinant phase .lambda.J19 was sequenced according to the dideoxy chain termination method. In addition to the retroviral structural genes gag, pol, and env, a novel open reading frame (ORF) was identified in the 3' region of the viral genome and designated ORF-R. The ORF-R coding region, which has subsequently been renamed nef, encodes a 206 amino acid protein that slightly overlaps the 3' end of the env gene and the 5' portion of the U3 region of the viral long terminal repeat (LTR). Nucleic acids encoding this protein and the precise amino acid sequence of the Nef are disclosed in this application. These products are useful for the generation of immunological reagents to facilitate the detection of LAV.
    Type: Grant
    Filed: February 14, 1994
    Date of Patent: January 6, 1998
    Assignee: Institut Pasteur and Centre National de la Recherche Scientifique
    Inventors: Marc Alizon, Pierre Sonigo, Cole Stewart, Oliver Danos, Simon Wain-Hobson
  • Non-cleavable GP160 glycoproteins of HIV
    Patent number: 5672689
    Abstract: A viral vector comprising at least a portion of the genome of the HIV virus, a gene encoding gp160 glycoprotein of the envelope of the HIV virus, as well as the elements providing for the expression of the glycoprotein in cells, wherein the gp160 is expressed as a non-cleavable protein.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: September 30, 1997
    Assignee: Transgene S.A. and Institute Pasteur
    Inventors: Marie-Paule Kieny, Guy Rautmann, Jean-Pierre Lecocq, Simon Wain Hobson, Marc Girard, Luc Montagnier
  • Variant of LAV viruses
    Patent number: 5034511
    Abstract: A variant of a LAV virus, designated LAV.sub.ELI and capable of causing AIDS. The cDNA and antigens of the LAV.sub.ELI virus can be used for the diagnosis of AIDS and pre-AIDS.
    Type: Grant
    Filed: April 13, 1987
    Date of Patent: July 23, 1991
    Assignee: Institut Pasteur
    Inventors: Marc Alizon, Pierre Sonigo, Simon Wain-Hobson, Luc Montagnier
  • Variant of LAV viruses
    Patent number: 5030714
    Abstract: A variant of the LAV virus, designated LAV.sub.MAL and capable of causing AIDS. The cDNA and antigens of the LAV.sub.MAL virus can be used for the diagnosis of AIDS and pre-AIDS.
    Type: Grant
    Filed: April 13, 1987
    Date of Patent: July 9, 1991
    Assignee: Institut Pasteur
    Inventors: Marc Alizon, Pierre Sonigo, Simon Wain-Hobson, Luc Montagnier
  • Isolation, molecular cloning and sequencing of an HIV-1 isolate from a Gabonese donor
    Patent number: 5019510
    Abstract: A new strain of Human Immunodeficiency Virus (HIV), which is the major etiological agent of Acquired Immune Deficiency Syndrome (AIDS), is identified. The new strain, products derived from the new strain, a diagnostic method for detecting antibodies to the strain in biological fluids, and a diagnostic kit for carrying out the method are described.
    Type: Grant
    Filed: October 28, 1987
    Date of Patent: May 28, 1991
    Assignee: Institut Pasteur
    Inventors: Simon Wain-Hobson, Thierry Huet, Eric Delaporte, Francoise Brun-Vezinet