Patents by Inventor Simona Barzu-Le-Roux

Simona Barzu-Le-Roux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Canine GHRH gene, polypeptides and methods of use
    Patent number: 7468273
    Abstract: The present invention relates to a canine pre-proGHRH polypeptide, a canine mature GHRH peptide, an isolated polynucleotide which encodes the canine pre-proGHRH or the canine mature GHRH. The invention also encompasses vectors encoding and expressing the canine pre-proGHRH or the canine GHRH which can be used to treat disease and growth hormone deficiencies by gene therapy in vertebrates, in particular in dogs.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: December 23, 2008
    Assignee: Meial Limited
    Inventors: Laurent Bernard Fisher, Nathalie Michele Cachet, Simona Barzu-Le-Roux
  • Canine pre-proGHRH and mature GHRH genes
    Patent number: 7351815
    Abstract: The present invention relates to a canine pre-proGHRH polypeptide, a canine mature GHRH peptide, an isolated polynucleotide which encodes the canine pre-proGHRH or the canine mature GHRH. The invention also encompasses vectors encoding and expressing the canine pre-proGHRH or the canine GHRH which can be used to treat disease and growth hormone deficiencies by gene therapy in vertebrates, in particular in dogs.
    Type: Grant
    Filed: May 3, 2004
    Date of Patent: April 1, 2008
    Assignee: Merial Limited
    Inventors: Laurent Bernard Fisher, Nathalie Michele Cachet, Simona Barzu-Le Roux
  • DNA vaccines for farm animals, in particular bovines and porcines
    Patent number: 7078388
    Abstract: DNA vaccine against a pathogen affecting farm animals, in particular bovines or porcines, comprising a plasmid containing a nucleotide sequence encoding an immunogen of a pathogen of the animal species considered, under conditions allowing the in vivo expression of this sequence, and a cationic lipid containing a quaternary ammonium salt, of formula in which R1 is a saturated or unsaturated linear aliphatic radical having 12 to 18 carbon atoms, R2 is another aliphatic radical containing 2 or 3 carbon atoms, and X a hydroxyl or amine group, this lipid being preferably DMRIE.
    Type: Grant
    Filed: January 16, 2001
    Date of Patent: July 18, 2006
    Assignee: Merial
    Inventors: Jean-Christophe Francis Audonnet, Laurent Bernard Fischer, Simona Barzu-Le-Roux
  • DNA vaccines for farm animals, in particular bovines and porcines
    Publication number: 20060122142
    Abstract: DNA vaccine against a pathogen affecting farm animals, in particular bovines or porcines, comprising a plasmid containing a nucleotide sequence encoding an immunogen of a pathogen of the animal species considered, under conditions allowing the in vivo expression of this sequence, and a cationic lipid containing a quaternary ammonium salt, of formula in which R1 is a saturated or unsaturated linear aliphatic radical having 12 to 18 carbon atoms, R2 is another aliphatic radical containing 2 or 3 carbon atoms, and X a hydroxyl or amine group, this lipid being preferably DMRIE.
    Type: Application
    Filed: January 30, 2006
    Publication date: June 8, 2006
    Inventors: Jean-Christophe Audonnet, Laurent Fischer, Simona Barzu-Le-Roux
  • Canine GHRH gene, polypeptides and methods of use
    Publication number: 20050164946
    Abstract: The present invention relates to a canine pre-proGHRH polypeptide, a canine mature GHRH peptide, an isolated polynucleotide which encodes the canine pre-proGHRH or the canine mature GHRH. The invention also encompasses vectors encoding and expressing the canine pre-proGHRH or the canine GHRH which can be used to treat disease and growth hormone deficiencies by gene therapy in vertebrates, in particular in dogs.
    Type: Application
    Filed: December 17, 2004
    Publication date: July 28, 2005
    Inventors: Laurent Fischer, Nathalie Cachet, Simona Barzu-Le-Roux
  • Canine GHRH gene, polypeptides and methods of use
    Publication number: 20050064554
    Abstract: The present invention relates to a canine pre-proGHRH polypeptide, a canine mature GHRH peptide, an isolated polynucleotide which encodes the canine pre-proGHRH or the canine mature GHRH. The invention also encompasses vectors encoding and expressing the canine pre-proGHRH or the canine GHRH which can be used to treat disease and growth hormone deficiencies by gene therapy in vertebrates, in particular in dogs.
    Type: Application
    Filed: May 3, 2004
    Publication date: March 24, 2005
    Inventors: Laurent Fisher, Nathalie Cachet, Simona Barzu-Le-Roux
  • DNA vaccines for farm animals, in particular bovines and porcines
    Patent number: 6852705
    Abstract: Improved vaccines or immunogenic or immunological compositions, and methods for making and using the same.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: February 8, 2005
    Assignee: Merial
    Inventors: Jean-Christophe Francis Audonnet, Laurent Bernard Fischer, Simona Barzu-Le-Roux
  • Vaccination or immunization using a prime-boost regimen
    Publication number: 20040002472
    Abstract: Disclosed and claimed are methods and compositions and kits for the vaccination or immunization of an animal, such as a mammal, advantageously a bovine, involving a prime-boost regimen.
    Type: Application
    Filed: February 19, 2003
    Publication date: January 1, 2004
    Inventors: Jean-Christophe Francis Audonnet, Laurent Bernard Fischer, Simona Barzu-Le-Roux
  • DNA vaccines for farm animals, in particular bovines and porcines
    Publication number: 20030068360
    Abstract: Improved vaccines or immunogenic or immunological compositions, and methods for making and using the same.
    Type: Application
    Filed: January 19, 2001
    Publication date: April 10, 2003
    Inventors: Jean-Christophe Francis Audonnet, Laurent Bernard Fischer, Simona Barzu-Le-Roux
  • DNA vaccines for farm animals, in particular bovines and porcines
    Publication number: 20020058021
    Abstract: DNA vaccine against a pathogen affecting farm animals, in particular bovines or porcines, comprising a plasmid containing a nucleotide sequence encoding an immunogen of a pathogen of the animal species considered, under conditions allowing the in vivo expression of this sequence, and a cationic lipid containing a quaternary ammonium salt, of formula 1
    Type: Application
    Filed: January 16, 2001
    Publication date: May 16, 2002
    Inventors: Jean-Christophe Francis Audonnet, Laurent Bernard Fischer, Simona Barzu-Le-Roux