Patents by Inventor Simona Margutti

Simona Margutti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microcapsule, system comprising microcapsules, method for changing the state of at least one such microcapsule and apparatus therefor
    Patent number: 8643938
    Abstract: The invention relates to a microcapsule, a system comprising microcapsules, and a corresponding method and apparatus, the microcapsule (11) comprising a core (12) which is encapsulated by an envelope (14) and in which at least one particle (16) having a motion component (17) and an indication component (18) is provided, the substance of the core (12) being capable of being transferred, at least for a short time, by an input of energy from a solid state or higher-viscosity state to a low-viscosity state, the at least one particle (16) being capable of undergoing a change in its position and/or orientation due to an input of energy occurring during the low-viscosity state of the substance of the core (12), and the substance of the core (12) reverting back, upon completion of the energy input, to the solid state or higher-viscosity state, thereby immobilizing the at least one particle (16) in its new position and/or orientation.
    Type: Grant
    Filed: July 8, 2009
    Date of Patent: February 4, 2014
    Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten For-Schung e.V.
    Inventors: Simona Margutti, Florian Rothfuss, Karola Rath, Simon Voigt
  • MICROCAPSULE, SYSTEM COMPRISING MICROCAPSULES, METHOD FOR CHANGING THE STATE OF AT LEAST ONE MICROCAPSULE AND APPARATUS THEREFOR
    Publication number: 20110180745
    Abstract: The invention relates to a microcapsule, a system comprising microcapsules, and a corresponding method and apparatus, the microcapsule (11) comprising a core (12) which is encapsulated by an envelope (14) and in which at least one particle (16) having a motion component (17) and an indication component (18) is provided, the substance of the core (12) being capable of being transferred, at least for a short time, by an input of energy from a solid state or higher-viscosity state to a low-viscosity state, the at least one particle (16) being capable of undergoing a change in its position and/or orientation due to an input of energy occurring during the low-viscosity state of the substance of the core (12), and the substance of the core (12) reverting back, upon completion of the energy input, to the solid state or higher-viscosity state, thereby immobilising the at least one particle (16) in its new position and/or orientation. (Cf. FIG. 1).
    Type: Application
    Filed: July 8, 2009
    Publication date: July 28, 2011
    Inventors: Simona Margutti, Florian Rothfuss, Karola Rath, Simon Voigt
  • Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
    Patent number: 7579324
    Abstract: This invention features a compound of the following formula: T-(-L-C)m, T is a transportophore, L is a bond or a linker having a molecular weight up to 240 dalton, C is a non-antibiotic therapeutic agent, and m is 1, 2, 3, 4, 5, 6, 7, or 8, in which the transportophore has an immune selectivity ratio of at least 2, the transportophore is covalently bonded to the non-antibiotic therapeutic agent via the bond or the linker, and the compound has an immune selectivity ratio of at least 2.
    Type: Grant
    Filed: February 14, 2003
    Date of Patent: August 25, 2009
    Assignee: c-a-i-r biosciences GmbH
    Inventors: Michael Burnet, Jan-Hinrich Guse, Hans-Jurgen Gutke, Albert Beck, Georgia Tsotsou, Irina Droste-Borel, Jeannette Reichert, Kattie Luyten, Maximilian Busch, Michael Wolff, Moussa Khobzaoui, Simona Margutti, Thomas Meindl, Gene Kim, Laurence Barker
  • Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
    Publication number: 20050171342
    Abstract: This invention features a compound of the following formula: T-(-L-C)m, T is a transportophore, L is a bond or a linker having a molecular weight up to 240 dalton, C is a non-antibiotic therapeutic agent, and m is 1, 2, 3, 4, 5, 6, 7, or 8, in which the transportophore has an immune selectivity ratio of at least 2, the transportophore is covalently bonded to the non-antibiotic therapeutic agent via the bond or the linker, and the compound has an immune selectivity ratio of at least 2.
    Type: Application
    Filed: February 14, 2003
    Publication date: August 4, 2005
    Inventors: Michael Burnet, Jan-Hinrich Guse, Hans-Jurgen Gutke, Albert Beck, Georgia Tsotsou, Irina Droste-Borel, Jeannette Reichert, Kattie Luyten, Maximilian Busch, Michael Wolff, Moussa Khobzaoui, Simona Margutti, Thomas Meindl, Gene Kim, Laurent Barker
  • Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
    Publication number: 20040186063
    Abstract: This invention features a compound of the following formula:
    Type: Application
    Filed: August 20, 2003
    Publication date: September 23, 2004
    Inventors: Hans-Jurgen Gutke, Christian Flohr, Albert Beck, Simona Margutti, Mary Eggers, Jan-Hinrich Guse, Moussa Khobzaoui, Michael Burnet
  • Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
    Publication number: 20040087517
    Abstract: This invention features a compound of the following formula:
    Type: Application
    Filed: February 14, 2003
    Publication date: May 6, 2004
    Inventors: Michael Burnet, Jan-Hinrich Guse, Hans-Jurgen Gutke, Albert Beck, Georgia Tsotsou, Irina Droste-Borel, Jeannette Reichert, Kattie Luyten, Maximilian Busch, Michael Wolff, Moussa Khobzaoui, Simona Margutti, Thomas Meindl, Gene Kim, Laurence Barker