Patents by Inventor Simona Maria Ceccarelli

Simona Maria Ceccarelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imidazole derivatives
    Patent number: 7091222
    Abstract: The present invention relates to imidazole derivatives of the general formula wherein R1, R2, R3 and R4 are as defined hereinabove. This invention also relates to the compound's pharmaceutically acceptable salt and processes for the preparation thereof. These compounds can be used for the manufacture of pharmaceutical compositions for the treatment and prevention of mGluR5 receptor mediated disorders. These compounds are useful, inter alia, in the treatment or prevention of acute and/or chronic neurological disorders such as psychosis, epilepsy, schizophrenia, Alzheimer's disease, cognitive disorders and memory deficit disorders, as well as chronic and acute pain.
    Type: Grant
    Filed: June 23, 2004
    Date of Patent: August 15, 2006
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Bernd Buettelmann, Simona Maria Ceccarelli, Georg Jaeschke, Sabine Kolczewski, Richard Hugh Philip Porter, Eric Vieira
  • Heteroaryl-substituted imidazole derivatives
    Publication number: 20040254179
    Abstract: The present invention relates to imidazole derivatives of the general formula 1
    Type: Application
    Filed: June 12, 2004
    Publication date: December 16, 2004
    Inventors: Bernd Buettelmann, Simona Maria Ceccarelli, Georg Jaeschke, Sabine Kolczewski, Richard Hugh Philip Porter, Eric Vieira
  • Imidazole derivatives
    Publication number: 20040248888
    Abstract: The present invention relates to imidazole derivatives of formula I 1
    Type: Application
    Filed: June 2, 2004
    Publication date: December 9, 2004
    Inventors: Bernd Buettelmann, Simona Maria Ceccarelli, Georg Jaeschke, Sabine Kolczewski, Richard Hugh Philip Porter, Eric Vieira
  • Imidazole derivatives
    Publication number: 20040229917
    Abstract: The present invention provides 4-[1-Aryl-imidazol-4-ylethynyl]-2-alkyl-pyridine and 1-heteroaryl-imidazol-4-ylethynyl]-2-alkyl-pyridine derivatives and pharmaceutically acceptable salts thereof for the treatment or prevention of disorders mediated in full or in part by metabotropic glutamate receptor 5. These disorders include, e.g. acute, traumatic and chronic degenerative processes of the nervous system, such as Alzheimer's disease, senile dementia, Parkinson's disease, Huntington's chorea, amyotrophic lateral sclerosis and multiple sclerosis, psychiatric diseases, such as schizophrenia and anxiety, depression, pain and drug dependency.
    Type: Application
    Filed: March 8, 2004
    Publication date: November 18, 2004
    Inventors: Bernd Buettelmann, Simona Maria Ceccarelli, Georg Jaeschke, Sabine Kolczewski, Richard Hugh Philip Porter, Eric Vieira
  • Amino-piperidine derivatives
    Publication number: 20040167166
    Abstract: The present invention relates to compounds of the general formula 1
    Type: Application
    Filed: February 13, 2004
    Publication date: August 26, 2004
    Inventors: Daniela Alberati-Giani, Simona Maria Ceccarelli, Emmanuel Pinard, Henri Stalder