Patents by Inventor Simona Polo

Simona Polo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HECT E3 LIGASE INHIBITORS AND USES THEREOF
    Publication number: 20220339163
    Abstract: The present invention relates to tricyclic derivatives of formula (I), which are useful as inhibitors of HECT-domain-containing E3 ligases, in particular NEDD4. The present invention also refers to pharmaceutical compositions comprising compounds of formula (I), to their medical use and to their process of preparation.
    Type: Application
    Filed: June 3, 2020
    Publication date: October 27, 2022
    Applicants: IFOM - FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE, IEO - ISTITUTO EUROPEO DI ONCOLOGIA S.R.L.
    Inventors: Sebastiano PASQUALATO, Maurizio PASI, Raffaella AMICI, Mario VARASI, Ciro MERCURIO, Luca SARTORI, Simona POLO, Elena MASPERO, Giovanni FAGA'
  • RANTES mutants and therapeutic applications thereof
    Patent number: 7164000
    Abstract: RANTES mutants characterised by the substitution or addition of amino acids at the N-terminal of RANTES wild-type sequence and in the N-loop and/or 40's loop regions of RANTES wild-type sequence, and their use as anti-HIV, anti-allergic or anti-inflammatory agents.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: January 16, 2007
    Assignee: Fondazione Centro San Raffaele Del Monte Tabor
    Inventors: Paolo Lusso, Simona Polo
  • Rantes mutants and therapeutic applications thereof
    Publication number: 20030216549
    Abstract: RANTES mutants characterised by the substitution or addition of amino acids at the N-terminal of RANTES wild-type sequence and in the N-loop and/or 40's loop regions of RANTES wild-type sequence, and their use as anti-HIV, anti-allergic or anti-inflammatory agents.
    Type: Application
    Filed: March 28, 2003
    Publication date: November 20, 2003
    Applicant: FONDAZIONE CENTRO SAN RAFFAELLE DEL MONTE TABOR
    Inventors: Paolo Lusso, Simona Polo
  • Rantes mutants and therapeutic applications thereof
    Patent number: 6608177
    Abstract: RANTES mutants characterized by the substitution or addition of amino acids at the N-terminal or RANTES wild-type sequence and in the N loop and/or 40′ loop regions of RNATES wild-type sequence, and their use as anti-HIV, anti-allergic or anti-inflammatory agents.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: August 19, 2003
    Assignee: Fondazione Centro San Raffaele del Monte Tabor
    Inventors: Paolo Lusso, Simona Polo