Patents by Inventor Simone Barbero

Simone Barbero has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240033749
    Abstract: A heavy-duty shredder, in particular for use in forestry, has a frame; a rotor, which is mounted on the frame so that it can rotate about an axis of rotation and has a drum coaxial with the axis of rotation; a plurality of annular discoidal sectors extending around the drum, integral with the drum and distributed along the axis of rotation so as to form annular cavities between the adjacent annular discoidal sectors; a plurality of first teeth integral with the drum and arranged in the annular cavities between two adjacent annular discoidal sectors; and a plurality of second teeth integral with the drum and aligned with the annular discoidal sectors.
    Type: Application
    Filed: July 29, 2022
    Publication date: February 1, 2024
    Inventor: Simone Barbero
  • Publication number: 20220397579
    Abstract: The invention relates to methods and kits for quantitating radiation exposure in a subject exposed to radiation, at risk of exposure to radiation or suspected of having been exposed to radiation. In embodiments, the present disclosure provides multiplexed immunoassays for quantifying amounts of biomarkers for assessing radiation exposure in a sample. Also provided herein are kits for performing the multiplexed assays.
    Type: Application
    Filed: November 4, 2020
    Publication date: December 15, 2022
    Inventors: Sunsanee Kanjananimmanont, Sudeep Kumar, Navaratnam Manjula, Simone Barbero, Martin Stengelin, George Sigal
  • Patent number: 11467161
    Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: October 11, 2022
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Simone Barbero, Eli N. Glezer, Anu Mathew, Mingyue Wang
  • Publication number: 20220299514
    Abstract: The present invention relates to methods of diagnosing breast cancer in a patient, as well as methods of monitoring the progression of breast cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen, The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: February 9, 2022
    Publication date: September 22, 2022
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Simone Barbero, Eli N. Glezer, Anu Mathew
  • Publication number: 20220196668
    Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: March 14, 2022
    Publication date: June 23, 2022
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Simone Barbero, Eli N. Glezer, Anu Mathew, Mingyue Wang
  • Patent number: 11327076
    Abstract: The present invention relates to methods of diagnosing breast cancer in a patient, as well as methods of monitoring the progression of breast cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: May 10, 2022
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Simone Barbero, Eli N. Glezer, Anu Mathew
  • Publication number: 20190265243
    Abstract: The present invention relates to methods of diagnosing breast cancer in a patient, as well as methods of monitoring the progression of breast cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: October 11, 2018
    Publication date: August 29, 2019
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Simone Barbero, Eli N. Glezer, Anu Mathew
  • Patent number: 9976472
    Abstract: A method of operating a cooling circuit of an internal combustion engine is disclosed. The engine is equipped with an engine head, and the cooling circuit includes a pump configured to deliver a variable flow of coolant through the cooling circuit. A coolant flow rate to be delivered by the pump is calculated as a function of an engine load, an engine speed and a desired engine head temperature, and the pump is operated to deliver the calculated coolant flow rate.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: May 22, 2018
    Assignee: GM GLOBAL TECHNOLOGY OPERATIONS LLC
    Inventors: Michele Bilancia, Simone Barbero, Simone Bambagioni, Salvatore Mafrici
  • Publication number: 20170242012
    Abstract: The present invention relates to methods of diagnosing breast cancer in a patient, as well as methods of monitoring the progression of breast cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: April 17, 2017
    Publication date: August 24, 2017
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Simone Barbero, Eli N. Glezer, Anu Mathew
  • Publication number: 20170205418
    Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: December 21, 2016
    Publication date: July 20, 2017
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Simone Barbero, Eli N. Glezer, Anu Mathew, Mingyue Wang
  • Publication number: 20160230642
    Abstract: A method of operating a cooling circuit of an internal combustion engine is disclosed. The engine is equipped with an engine head, and the cooling circuit includes a pump configured to deliver a variable flow of coolant through the cooling circuit. A coolant flow rate to be delivered by the pump is calculated as a function of an engine load, an engine speed and a desired engine head temperature, and the pump is operated to deliver the calculated coolant flow rate.
    Type: Application
    Filed: February 9, 2016
    Publication date: August 11, 2016
    Applicant: GM GLOBAL TECHNOLOGY OPERATIONS LLC
    Inventors: Michele BILANCIA, Simone BARBERO, Simone BAMBAGIONI, Salvatore MAFRICI
  • Patent number: 9175617
    Abstract: A system and method can control exhaust braking in a vehicle. The vehicle includes an engine system. The engine system includes internal combustion engine, an intake manifold, a control module, an exhaust system, and a variable geometry turbocharger (VGT) having a turbine. The turbine includes turbine blades and vanes movable with respect to the turbine blades. The method includes the following: (a) receiving an exhaust brake torque request; (b) determining target pumping losses in the internal combustion engine based on the exhaust brake torque request; (c) determining a target exhaust gas pressure within the exhaust system based on the target pumping losses; and (d) determining a target vane position of the vanes based on the target exhaust gas pressure, wherein the target vane position yields an exhaust brake torque in accordance with the exhaust brake torque request.
    Type: Grant
    Filed: August 8, 2013
    Date of Patent: November 3, 2015
    Assignee: GM Global Technology Operations LLC
    Inventors: Luca Scavone, Simone Barbero, Francesco Castorina, Francesco Cianflone, Andrea Di Giovanni, Andrea De Vito
  • Publication number: 20150040859
    Abstract: A system and method can control exhaust braking in a vehicle. The vehicle includes an engine system. The engine system includes internal combustion engine, an intake manifold, a control module, an exhaust system, and a variable geometry turbocharger (VGT) having a turbine. The turbine includes turbine blades and vanes movable with respect to the turbine blades. The method includes the following: (a) receiving an exhaust brake torque request; (b) determining target pumping losses in the internal combustion engine based on the exhaust brake torque request; (c) determining a target exhaust gas pressure within the exhaust system based on the target pumping losses; and (d) determining a target vane position of the vanes based on the target exhaust gas pressure, wherein the target vane position yields an exhaust brake torque in accordance with the exhaust brake torque request.
    Type: Application
    Filed: August 8, 2013
    Publication date: February 12, 2015
    Applicant: GM GLOBAL TECHNOLOGY OPERATIONS LLC
    Inventors: Luca Scavone, Simone Barbero, Francesco Castorina, Francesco Cianflone, Andrea Di Giovanni, Andrea De Vito
  • Publication number: 20140358400
    Abstract: A system according to the principles of the present disclosure includes an exhaust braking enabling module, a driver torque module, and an engine actuator control module. The exhaust braking enabling module selectively enables exhaust braking based on driver input and independent of an accelerator pedal position. The driver torque module selectively determines a driver torque request based on a powertrain braking torque capacity when exhaust braking is enabled. The engine actuator control module controls fuel delivery to cylinders of an engine and a vane position of a turbocharger based on the driver torque request.
    Type: Application
    Filed: May 29, 2013
    Publication date: December 4, 2014
    Applicant: GM Global Technology Operations LLC
    Inventors: Christopher E. Whitney, CHAD E. MARLETT, LUCA SCAVONE, KELLY T. JOZEFOWICZ, TRENTON W. HAINES, SIMONE BARBERO
  • Publication number: 20140309263
    Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: January 31, 2014
    Publication date: October 16, 2014
    Applicant: MESO SCALE TECHNOLOGIES, LLC
    Inventors: Simone Barbero, Eli N. Glezer, Anu Mathew, Mingyue Wang
  • Publication number: 20140221368
    Abstract: The present invention relates to methods of diagnosing breast cancer in a patient, as well as methods of monitoring the progression of breast cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: January 30, 2014
    Publication date: August 7, 2014
    Applicant: Meso Scale Technologies, LLC
    Inventors: Simone Barbero, Eli N. Glezer, Anu Mathew
  • Patent number: 8676475
    Abstract: A method is provided for regenerating a diesel particulate filter within a diesel engine system that includes, but is not limited to at least a combustion chamber defined by a reciprocating piston inside a cylinder, at least an exhaust valve for cyclically open the combustion chamber towards an exhaust line, and the diesel particulate filter located in the exhaust line, wherein the method comprises injecting an amount of fuel into the combustion chamber by means of least two consecutive after-injection pulses (AIP1-AIP3), each of which starts (SOI) after the piston has passed the top dead center (TDC), and sufficiently near to the latter for the fuel to burn at least partially inside the combustion chamber.
    Type: Grant
    Filed: August 17, 2010
    Date of Patent: March 18, 2014
    Assignee: GM Global Technology Operations LLC
    Inventors: Stefano Cassani, Davide Mercuri, Simone Barbero, Pierluigi Rellecati
  • Patent number: 8626421
    Abstract: A method is provided for reducing emissions behind a catalytic converter in an exhaust gas stream of the engine. The method includes, but is not limited to controlling a power supply to a glowplug of a compression-ignition engine. The glowplug is activated if a set of at least two input values remains in a first characteristic region of an input parameter space for at least a predetermined activation time. The first characteristic region consists of one ore more contiguous regions of the input parameter space.
    Type: Grant
    Filed: August 17, 2010
    Date of Patent: January 7, 2014
    Assignee: GM Global Technology Operations LLC
    Inventors: Timo Fink, Andrei Kanev, Stefano Cassani, Simone Barbero
  • Patent number: 8489308
    Abstract: A method and a control system are provided for estimating oxygen concentration downstream a diesel oxidation catalyst within a diesel engine system. The method includes, but is not limited to at least an intake manifold, a combustion chamber, an exhaust manifold, and the diesel oxidation catalyst located in the exhaust line upstream a diesel particulate filter, the method comprising: determining unburned fuel mass flow ejected from the combustion chamber, determining air mass fraction in the exhaust manifold, estimating air mass fraction downstream the diesel oxidation catalyst as a function of said unburned fuel mass flow and said air mass fraction in the exhaust manifold, estimating oxygen concentration downstream the diesel oxidation catalyst as a function of the estimated air mass fraction downstream the diesel oxidation catalyst.
    Type: Grant
    Filed: August 17, 2010
    Date of Patent: July 16, 2013
    Assignee: GM Global Technology Operations LLC
    Inventors: Igor Zanetti, Simone Barbero, Stefano Cassani
  • Patent number: 8375776
    Abstract: A method is provided for determining an in-cylinder pressure curve representative of the evolution of the pressure within a cylinder of a multi-cylinder internal combustion engine. The method includes, but is not limited to setting a timeframe during the engine functioning, sampling pressure within at least two sensed cylinders of the engine, the samplings being performed during not contemporary sampling periods within the assumed timeframe, in order to acquire a partial in-cylinder pressure curve for each of the sensed cylinders, and using the partial in-cylinder pressure curves for reconstructing a whole in-cylinder pressure curve.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: February 19, 2013
    Assignee: GM Global Technology Operations LLC
    Inventors: Manuel Tugnolo, Alessandro Catanese, Simone Barbero