Patents by Inventor Simone Bigi

Simone Bigi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-amino-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide derivatives as inhibitors of MRGX2
    Patent number: 12247015
    Abstract: Disclosed are compounds of Formula (1), tautomers thereof, and pharmaceutically acceptable salts of the compounds or tautomers, wherein L, R1, R2, R3, R4 and R5 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula (1), to pharmaceutical compositions which contain them, and to their use for treating diseases, disorders or conditions associated with MRGX2.
    Type: Grant
    Filed: April 28, 2020
    Date of Patent: March 11, 2025
    Assignee: SOLENT THERAPEUTICS, LLC
    Inventors: Simone Bigi, Alison L. Chambers, Tony Gibson, Jason Pickens, Steve Swann, Angie Vassar, Feng Zhou, Mitsunori Kono, Masaki Seto, Zenyu Shiokawa
  • 3-AMINO-4H-BENZO[E][1,2,4]THIADIAZINE 1,1-DIOXIDE DERIVATIVES AS INHIBITORS OF MRGX2
    Publication number: 20220119361
    Abstract: Disclosed are compounds of Formula (1), tautomers thereof, and pharmaceutically acceptable salts of the compounds or tautomers, wherein L, R1, R2, R3, R4 and R5 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula (1), to pharmaceutical compositions which contain them, and to their use for treating diseases, disorders or conditions associated with MRGX2.
    Type: Application
    Filed: April 28, 2020
    Publication date: April 21, 2022
    Inventors: Simone BIGI, Alison L. CHAMBERS, Tony GIBSON, Jason PICKENS, Steve SWANN, Angie VASSAR, Feng ZHOU, Mitsunori KONO, Masaki SETO, Zenyu SHIOKAWA
  • Heteroarylamide inhibitors of TBK1
    Patent number: 9994547
    Abstract: Disclosed are compounds of formula 1: which are useful as inhibitors of TBK1. Also disclosed are pharmaceutical compositions which contain the compounds, methods for treatment of conditions associated with TBK1, and processes for making the compounds and intermediates thereof.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: June 12, 2018
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Simone Bigi, Walter Keung, Steve Swann, Phong H. Vu, Steven John Woodhead, Anthony R. Gangloff
  • HETEROARYLAMIDE INHIBITORS OF TBK1
    Publication number: 20170313675
    Abstract: Disclosed are compounds of formula 1: which are useful as inhibitors of TBK1. Also disclosed are pharmaceutical compositions which contain the compounds, methods for treatment of conditions associated with TBK1, and processes for making the compounds and intermediates thereof.
    Type: Application
    Filed: October 2, 2015
    Publication date: November 2, 2017
    Inventors: Simone Bigi, Walter Keung, Steve Swann, Phong H. Vu, Steven John Woodhead, Anthony R. Gangloff