Abstract: New soft capsules are described having within them a fill which contains thyroid hormones such as thyroxine T4 or triiodothyronine T3) and a high amylose-starch, optionally associated with vegetable hydrocolloids and/or glycerol. Compared to traditional capsules, these capsules have a strong and unexpected increase in the stability of T4 or T3 during storage.

Abstract: A plunger is described, which is configured for application in a syringe-type pump for a machine for encapsulation of soft capsules, for adjusting the quantity of filler to be injected into said soft capsules, said plunger having an axially developing structure and comprising: a tip (31) and a sealing body (32) connected to the tip, adapted to penetrate into said syringe-type pump (P), a first mechanical abutment ring (33), fixedly positioned, connected to said sealing body, a plunger stopper housing (34), connected to said fixedly positioned mechanical abutment ring, a second mechanical abutment ring (35), axially adjustable, a mechanical dowel (37) protruding from said stopper housing, an adjuster nut (36) adapted to be screwed on said mechanical dowel (37) for adjusting the axial position of the second ring (35) relative to the first ring, so as to adjust the axial position of the plunger in said syringe-type pump (P).

Abstract: Disclosed are soft gelatin capsules comprising a gelatin shell, a plasticiser, water, and optionally a calcium salt and a filling containing a dispersed or solubilised medicament comprising gelatin with gelling power, hydrolysed gelatin, glycerol, water, pectin and gellan gum. The formulations according to the invention allow gradual release of the active ingredient, regardless of pH.

Abstract: New soft gelatin capsules highly protected against the degradation of the active ingredient contained therein and highly resistant to hydration are described. The capsular wall is characterized by containing hydroxypropyl beta cyclodextrin in low quantity with respect to the weight of the wall and sub-stoichiometric with respect to that necessary for complexing the drug contained within the capsule. The new capsules are storage-stable, avoid the development of active ingredient by-products and maintain a high weight constancy, i.e. low hygroscopy.

Abstract: New soft capsules are described having within them a fill which contains thyroid hormones such as thyroxine T4 or triiodothyronine T3) and a high amylose-starch, optionally associated with vegetable hydrocolloids and/or glycerol. Compared to traditional capsules, these capsules have a strong and unexpected increase in the stability of T4 or T3 during storage.

Abstract: New soft gelatin capsules highly protected against the degradation of the active ingredient contained therein and highly resistant to hydration are described. The capsular wall is characterized by containing hydroxypropyl beta cyclodextrin in low quantity with respect to the weight of the wall and sub-stoichiometric with respect to that necessary for complexing the drug contained within the capsule. The new capsules are storage-stable, avoid the development of active ingredient by-products and maintain a high weight constancy, i.e. low hygroscopy.

Abstract: Disclosed are soft gelatin capsules comprising a gelatin shell, a plasticiser, water, and optionally a calcium salt and a filling containing a dispersed or solubilised medicament comprising gelatin with gelling power, hydrolysed gelatin, glycerol, water, pectin and gellan gum. The formulations according to the invention allow gradual release of the active ingredient, regardless of pH.

Abstract: The invention discloses stable formulations of acetylsalicylic acid or salts thereof, omega-3 fatty acids and amylose in soft gelatin capsules.

Abstract: The invention discloses stable formulations of acetylsalicylic acid or salts thereof, omega-3 fatty acids and amylose in soft gelatin capsules.