Patents by Inventor Simone Gauch
Simone Gauch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8008475Abstract: The present invention involves a process for the isolation of nucleic acids on surfaces by means of at least the following steps: charging of a surface from a given direction with nucleic acids; immobilization of the nucleic acids on the surface; release of the immobilized nucleic acids from the surface; and removal of the released nucleic acids essentially in the direction of charging. Preferably the loading takes place from the top.Type: GrantFiled: March 28, 2000Date of Patent: August 30, 2011Assignee: QIAGEN GmbHInventors: Helge Bastian, Simone Gauch, Uwe Oelmüller, Susanne Ullmann
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Publication number: 20100159460Abstract: New processes and equipment to isolate and purify nucleic acids on surfaces are provided. The invention focuses on processes which use surfaces, for example, porous membranes, on which the nucleic acids are immobilized in a simple manner from the sample containing the nucleic acids and can be released again by way of simple procedural steps, whereby the simple performance of the process according to the invention makes it possible to perform the processes specifically in a fully automatic manner. An additional aspect of the present invention focuses on binding the nucleic acids to an immobile phase, especially to a membrane, in such a way and manner, that they can be released without difficulty during an additional reaction stage from this phase and, if desired, can be used in other applications, such as restriction digestion, RT, PCR or RT-PCR, or in any of the suitable analyses or enzyme reactions mentioned in the disclosure.Type: ApplicationFiled: September 11, 2009Publication date: June 24, 2010Inventors: Simone Gauch, Helge Bastian, Susanne Ullmann, Uwe Oelmüller, Martin Weber, Guido Fuhrmann, Joachim Schorr
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Publication number: 20100021925Abstract: New processes and equipment to isolate and purify nucleic acids on surfaces are provided. The invention focuses on processes which use surfaces, for example, porous membranes, on which the nucleic acids are immobilized in a simple manner from the sample containing the nucleic acids and can be released again by way of simple procedural steps, whereby the simple performance of the process according to the invention makes it possible to perform the processes specifically in a fully automatic manner. An additional aspect of the present invention focuses on binding the nucleic acids to an immobile phase, especially to a membrane, in such a way and manner, that they can be released without difficulty during an additional reaction stage from this phase and, if desired, can be used in other applications, such as restriction digestion, RT, PCR or RT-PCR, or in any of the suitable analyses or enzyme reactions mentioned in the disclosure.Type: ApplicationFiled: September 11, 2009Publication date: January 28, 2010Inventors: Simone Gauch, Helge Bastian, Susanne Ullmann, Uwe Oelmüller, Martin Weber, Guido Fuhrmann, Joachim Schorr
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Patent number: 7074916Abstract: The present invention pertains to a process for the chromatographic separation of nucleic acid mixtures into their double-stranded and single-stranded nucleic acid fractions by simultaneously absorbing said nucleic acids as a whole to a mineral support, followed by separation into double-stranded and single-stranded nucleic acids by fractional elution, or by selectively absorbing double-stranded or single-stranded nucleic acid of a liquid sample to a mineral support, as well as solutions and a kit for performing the process according to the invention.Type: GrantFiled: January 13, 2003Date of Patent: July 11, 2006Assignee: QIAGEN GmbHInventors: Helge Bastian, Simone Gauch, Metin Colpan, Petra Feuser
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Publication number: 20050244882Abstract: New processes and equipment to isolate and purify nucleic acids on surfaces are provided. The invention focuses on processes which use surfaces, for example, porous membranes, on which the nucleic acids are immobilized in a simple manner from the sample containing the nucleic acids and can be released again by way of simple procedural steps, whereby the simple performance of the process according to the invention makes it possible to perform the processes specifically in a fully automatic manner. An additional aspect of the present invention focuses on binding the nucleic acids to an immobile phase, especially to a membrane, in such a way and manner, that they can be released without difficulty during an additional reaction stage from this phase and, if desired, can be used in other applications, such as restriction digestion, RT, PCR or RT-PCR, or in any of the suitable analyses or enzyme reactions mentioned in the disclosure.Type: ApplicationFiled: June 17, 2005Publication date: November 3, 2005Inventors: Simone Gauch, Helge Bastian, Susanne Ullmann, Uwe Oelmuller, Martin Weber, Guido Fuhrmann, Joachim Schorr
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Patent number: 6946250Abstract: The present invention pertains to a process for the chromatographic separation of nucleic acid mixtures into their double-stranded and single-stranded nucleic acid fractions by simultaneously absorbing said nucleic acids as a whole to a mineral support, followed by separation into double-stranded and single-stranded nucleic acids by fractional elution, or by selectively absorbing double-stranded or single-stranded nucleic acid of a liquid sample to a mineral support, as well as solutions and a kit for performing the process according to the invention.Type: GrantFiled: December 4, 2001Date of Patent: September 20, 2005Assignee: Qiagen GmbHInventors: Helge Bastian, Simone Gauch, Metin Colpan, Petra Feuser
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Publication number: 20030224389Abstract: The present invention pertains to a process for the chromatographic separation of nucleic acid mixtures into their double-stranded and single-stranded nucleic acid fractions by simultaneously absorbing said nucleic acids as a whole to a mineral support, followed by separation into double-stranded and single-stranded nucleic acids by fractional elution, or by selectively absorbing double-stranded or single-stranded nucleic acid of a liquid sample to a mineral support, as well as solutions and a kit for performing the process according to the invention.Type: ApplicationFiled: January 13, 2003Publication date: December 4, 2003Applicant: Qiagen GmbHInventors: Helge Bastian, Simone Gauch, Metin Colpan, Petra Feuser
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Publication number: 20030152974Abstract: New processes and equipment to isolate and purify nucleic acids on surfaces are provided. The invention focuses on processes which use surfaces, for example, porous membranes, on which the nucleic acids are immobilized in a simple manner from the sample containing the nucleic acids and can be released again by way of simple procedural steps, whereby the simple performance of the process according to the invention makes it possible to perform the processes specifically in a fully automatic manner. An additional aspect of the present invention focuses on binding the nucleic acids to an immobile phase, especially to a membrane, in such a way and manner, that they can be released without difficulty during an additional reaction stage from this phase and, if desired, can be used in other applications, such as restriction digestion, RT, PCR or RT-PCR, or in any of the suitable analyses or enzyme reactions mentioned in the disclosure.Type: ApplicationFiled: November 20, 2002Publication date: August 14, 2003Inventors: Simone Gauch, Helge Bastian, Susanne Ullmann, Uwe Oelmuller, Martin Weber, Guido Fuhrmann, Joachim Schorr
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Publication number: 20020081619Abstract: The present invention pertains to a process for the chromatographic separation of nucleic acid mixtures into their double-stranded and single-stranded nucleic acid fractions by simultaneously absorbing said nucleic acids as a whole to a mineral support, followed by separation into double-stranded and single-stranded nucleic acids by fractional elution, or by selectively absorbing double-stranded or single-stranded nucleic acid of a liquid sample to a mineral support, as well as solutions and a kit for performing the process according to the invention.Type: ApplicationFiled: December 4, 2001Publication date: June 27, 2002Applicant: Qiagen GmbHInventors: Helge Bastian, Simone Gauch, Metin Colpan, Petra Feuser
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Patent number: 6258930Abstract: The use of multi-well blocks with more than 10 wells is suggested for breaking down biological samples in a ball mill, wherein the process which is to be carried out provides that the biological sample, disposed in a multi-well block with more than 10 wells, is broken down in a ball mill and that following this, proteins and/or nucleic acids are isolated. With the ball mill necessary for this task, with milling containers fixed thereto in a holder (10), the milling containers are designed as uniform well blocks (16) and can be fixed in a form-locking manner into the adapted, twist-preventing holder (10).Type: GrantFiled: March 2, 2000Date of Patent: July 10, 2001Assignee: Qiagen GmbHInventors: Simone Gauch, Helge Bastian, Manfred Roord, Uwe Orth, Radu Anghel
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Patent number: 6180778Abstract: The present invention pertains to a process for the chromatographic separation of nucleic acid mixtures into their double-stranded and single-stranded nucleic acid fractions by simultaneously absorbing said nucleic acids as a whole to a mineral support, followed by separation into double-stranded and single-stranded nucleic acids by fractional elution, or by selectively absorbing double-stranded or single-stranded nucleic acid of a liquid sample to a mineral support, as well as solutions and a kit for performing the process according to the invention.Type: GrantFiled: August 8, 1996Date of Patent: January 30, 2001Assignee: QIAGEN GmbHInventors: Helge Bastian, Simone Gauch, Metin Colpan, Petra Feuser