Patents by Inventor Simone Gauch

Simone Gauch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8008475
    Abstract: The present invention involves a process for the isolation of nucleic acids on surfaces by means of at least the following steps: charging of a surface from a given direction with nucleic acids; immobilization of the nucleic acids on the surface; release of the immobilized nucleic acids from the surface; and removal of the released nucleic acids essentially in the direction of charging. Preferably the loading takes place from the top.
    Type: Grant
    Filed: March 28, 2000
    Date of Patent: August 30, 2011
    Assignee: QIAGEN GmbH
    Inventors: Helge Bastian, Simone Gauch, Uwe Oelmüller, Susanne Ullmann
  • Publication number: 20100159460
    Abstract: New processes and equipment to isolate and purify nucleic acids on surfaces are provided. The invention focuses on processes which use surfaces, for example, porous membranes, on which the nucleic acids are immobilized in a simple manner from the sample containing the nucleic acids and can be released again by way of simple procedural steps, whereby the simple performance of the process according to the invention makes it possible to perform the processes specifically in a fully automatic manner. An additional aspect of the present invention focuses on binding the nucleic acids to an immobile phase, especially to a membrane, in such a way and manner, that they can be released without difficulty during an additional reaction stage from this phase and, if desired, can be used in other applications, such as restriction digestion, RT, PCR or RT-PCR, or in any of the suitable analyses or enzyme reactions mentioned in the disclosure.
    Type: Application
    Filed: September 11, 2009
    Publication date: June 24, 2010
    Inventors: Simone Gauch, Helge Bastian, Susanne Ullmann, Uwe Oelmüller, Martin Weber, Guido Fuhrmann, Joachim Schorr
  • Publication number: 20100021925
    Abstract: New processes and equipment to isolate and purify nucleic acids on surfaces are provided. The invention focuses on processes which use surfaces, for example, porous membranes, on which the nucleic acids are immobilized in a simple manner from the sample containing the nucleic acids and can be released again by way of simple procedural steps, whereby the simple performance of the process according to the invention makes it possible to perform the processes specifically in a fully automatic manner. An additional aspect of the present invention focuses on binding the nucleic acids to an immobile phase, especially to a membrane, in such a way and manner, that they can be released without difficulty during an additional reaction stage from this phase and, if desired, can be used in other applications, such as restriction digestion, RT, PCR or RT-PCR, or in any of the suitable analyses or enzyme reactions mentioned in the disclosure.
    Type: Application
    Filed: September 11, 2009
    Publication date: January 28, 2010
    Inventors: Simone Gauch, Helge Bastian, Susanne Ullmann, Uwe Oelmüller, Martin Weber, Guido Fuhrmann, Joachim Schorr
  • Patent number: 7074916
    Abstract: The present invention pertains to a process for the chromatographic separation of nucleic acid mixtures into their double-stranded and single-stranded nucleic acid fractions by simultaneously absorbing said nucleic acids as a whole to a mineral support, followed by separation into double-stranded and single-stranded nucleic acids by fractional elution, or by selectively absorbing double-stranded or single-stranded nucleic acid of a liquid sample to a mineral support, as well as solutions and a kit for performing the process according to the invention.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: July 11, 2006
    Assignee: QIAGEN GmbH
    Inventors: Helge Bastian, Simone Gauch, Metin Colpan, Petra Feuser
  • Publication number: 20050244882
    Abstract: New processes and equipment to isolate and purify nucleic acids on surfaces are provided. The invention focuses on processes which use surfaces, for example, porous membranes, on which the nucleic acids are immobilized in a simple manner from the sample containing the nucleic acids and can be released again by way of simple procedural steps, whereby the simple performance of the process according to the invention makes it possible to perform the processes specifically in a fully automatic manner. An additional aspect of the present invention focuses on binding the nucleic acids to an immobile phase, especially to a membrane, in such a way and manner, that they can be released without difficulty during an additional reaction stage from this phase and, if desired, can be used in other applications, such as restriction digestion, RT, PCR or RT-PCR, or in any of the suitable analyses or enzyme reactions mentioned in the disclosure.
    Type: Application
    Filed: June 17, 2005
    Publication date: November 3, 2005
    Inventors: Simone Gauch, Helge Bastian, Susanne Ullmann, Uwe Oelmuller, Martin Weber, Guido Fuhrmann, Joachim Schorr
  • Patent number: 6946250
    Abstract: The present invention pertains to a process for the chromatographic separation of nucleic acid mixtures into their double-stranded and single-stranded nucleic acid fractions by simultaneously absorbing said nucleic acids as a whole to a mineral support, followed by separation into double-stranded and single-stranded nucleic acids by fractional elution, or by selectively absorbing double-stranded or single-stranded nucleic acid of a liquid sample to a mineral support, as well as solutions and a kit for performing the process according to the invention.
    Type: Grant
    Filed: December 4, 2001
    Date of Patent: September 20, 2005
    Assignee: Qiagen GmbH
    Inventors: Helge Bastian, Simone Gauch, Metin Colpan, Petra Feuser
  • Publication number: 20030224389
    Abstract: The present invention pertains to a process for the chromatographic separation of nucleic acid mixtures into their double-stranded and single-stranded nucleic acid fractions by simultaneously absorbing said nucleic acids as a whole to a mineral support, followed by separation into double-stranded and single-stranded nucleic acids by fractional elution, or by selectively absorbing double-stranded or single-stranded nucleic acid of a liquid sample to a mineral support, as well as solutions and a kit for performing the process according to the invention.
    Type: Application
    Filed: January 13, 2003
    Publication date: December 4, 2003
    Applicant: Qiagen GmbH
    Inventors: Helge Bastian, Simone Gauch, Metin Colpan, Petra Feuser
  • Publication number: 20030152974
    Abstract: New processes and equipment to isolate and purify nucleic acids on surfaces are provided. The invention focuses on processes which use surfaces, for example, porous membranes, on which the nucleic acids are immobilized in a simple manner from the sample containing the nucleic acids and can be released again by way of simple procedural steps, whereby the simple performance of the process according to the invention makes it possible to perform the processes specifically in a fully automatic manner. An additional aspect of the present invention focuses on binding the nucleic acids to an immobile phase, especially to a membrane, in such a way and manner, that they can be released without difficulty during an additional reaction stage from this phase and, if desired, can be used in other applications, such as restriction digestion, RT, PCR or RT-PCR, or in any of the suitable analyses or enzyme reactions mentioned in the disclosure.
    Type: Application
    Filed: November 20, 2002
    Publication date: August 14, 2003
    Inventors: Simone Gauch, Helge Bastian, Susanne Ullmann, Uwe Oelmuller, Martin Weber, Guido Fuhrmann, Joachim Schorr
  • Publication number: 20020081619
    Abstract: The present invention pertains to a process for the chromatographic separation of nucleic acid mixtures into their double-stranded and single-stranded nucleic acid fractions by simultaneously absorbing said nucleic acids as a whole to a mineral support, followed by separation into double-stranded and single-stranded nucleic acids by fractional elution, or by selectively absorbing double-stranded or single-stranded nucleic acid of a liquid sample to a mineral support, as well as solutions and a kit for performing the process according to the invention.
    Type: Application
    Filed: December 4, 2001
    Publication date: June 27, 2002
    Applicant: Qiagen GmbH
    Inventors: Helge Bastian, Simone Gauch, Metin Colpan, Petra Feuser
  • Patent number: 6258930
    Abstract: The use of multi-well blocks with more than 10 wells is suggested for breaking down biological samples in a ball mill, wherein the process which is to be carried out provides that the biological sample, disposed in a multi-well block with more than 10 wells, is broken down in a ball mill and that following this, proteins and/or nucleic acids are isolated. With the ball mill necessary for this task, with milling containers fixed thereto in a holder (10), the milling containers are designed as uniform well blocks (16) and can be fixed in a form-locking manner into the adapted, twist-preventing holder (10).
    Type: Grant
    Filed: March 2, 2000
    Date of Patent: July 10, 2001
    Assignee: Qiagen GmbH
    Inventors: Simone Gauch, Helge Bastian, Manfred Roord, Uwe Orth, Radu Anghel
  • Patent number: 6180778
    Abstract: The present invention pertains to a process for the chromatographic separation of nucleic acid mixtures into their double-stranded and single-stranded nucleic acid fractions by simultaneously absorbing said nucleic acids as a whole to a mineral support, followed by separation into double-stranded and single-stranded nucleic acids by fractional elution, or by selectively absorbing double-stranded or single-stranded nucleic acid of a liquid sample to a mineral support, as well as solutions and a kit for performing the process according to the invention.
    Type: Grant
    Filed: August 8, 1996
    Date of Patent: January 30, 2001
    Assignee: QIAGEN GmbH
    Inventors: Helge Bastian, Simone Gauch, Metin Colpan, Petra Feuser