Abstract: The present invention relates to anti-human PD-L2 antibodies, or the antigen binding parts thereof, which specifically bind human PD-L2 such that PD-L2 binding to PD-1 is blocked, wherein preferably said antibodies or antigen binding parts do not bind to mouse PD-L2 and human PD-L1 but bind to cyno PD-L2, preferably as determined by FACS analysis. The present invention also relates to nucleotide sequences encoding the anti-human PD-L2 antibodies, vectors and cells containing the nucleotide sequences. The antibodies and/or compositions of the invention are useful in human therapy, e.g., cancer therapy, and/or in cell-line based bioassays for determining T cell signalling.

Abstract: The present invention relates to anti-human PD-L2 antibodies, or the antigen binding parts thereof, which specifically bind human PD-L2 such that PD-L2 binding to PD-1 is blocked, wherein preferably said antibodies or antigen binding parts do not bind to mouse PD-L2 and human PD-L1 but bind to cyno PD-L2, preferably as determined by FACS analysis. The present invention also relates to nucleotide sequences encoding the anti-human PD-L2 antibodies, vectors and cells containing the nucleotide sequences. The antibodies and/or compositions of the invention are useful in human therapy, e.g., cancer therapy, and/or in cell-line based bioassays for determining T cell signalling.

Abstract: An ear level part for a hearing device includes a body configured to be worn within a concha of a user's ear and a retention element arranged on the body and configured to bear against an antihelix of the user's ear, wherein a cable is arranged to electrically connect the ear level part with a behind the ear part of the hearing device, wherein the cable is run within the retention element and emerges from an end section thereof.

Abstract: The present invention relates to anti-human PD-L2 antibodies, or the antigen binding parts thereof, which specifically bind human PD-L2 such that PD-L2 binding to PD-1 is blocked, wherein preferably said antibodies or antigen binding parts do not bind to mouse PD-L2 and human PD-L1 but bind to cyno PD-L2, preferably as determined by FACS analysis. The present invention also relates to nucleotide sequences encoding the anti-human PD-L2 antibodies, vectors and cells containing the nucleotide sequences. The antibodies and/or compositions of the invention are useful in human therapy, e.g., cancer therapy, and/or in cell-line based bioassays for determining T cell signalling.

Abstract: A method for operating a hearing device including a component to be worn at least partially in an ear of a user and an active noise control (ANC) system is provided. The method includes capturing an audio with a microphone system, generating an audio signal based on the captured audio, and generating a feed-forward (FF) compensating signal based on the captured audio. The method includes monitoring the acoustic environment of the hearing device for presence of wind noise, and mixing the audio signal with the generated FF compensating signal at a ratio dependent on whether wind noise is detected to provide an acoustic output signal. A hearing device including an active noise control (ANC) system and a wind noise monitor is also provided.

Abstract: The invention relates to a heating element (20), in particular for heating user contact surfaces of a passenger compartment of a vehicle, comprising a) at least one heating zone in which at least one first electrical conductor strand is disposed for heating a passenger of the automotive vehicle; b) at least one additional second conductor strand for supplying electrical energy into the at least one first conductor strand for heating the heating zone; c) a contact area in which the at least one additional second conductor strand is connected, in an electrically conductive manner, to the at least one first conductor strand for heating the heating zone; and wherein at least one of the first or second conductor strands includes at least one filament-like inner strand core comprising a polyamide, a carbon fiber, a polypropylene, or a polyester and at least one jacket layer that includes silver, copper, gold, nickel, or an alloy thereof.

Abstract: The present invention relates to a ventilated seat having an insert with a seat portion, and having a flow control layer with first and second ports, a spacer having an inlay and a main portion, and a first fluid barrier where the inlay is substantially isolated from the main portion by a fluid-tight boundary. The present invention also relates to a ventilated seat having an insert with a seat portion and having a first flow control layer with at least one port, a first and a second spacer, and a fluid barrier comprising at least one port. The present invention also relates to a ventilated seat with an insert having a seat portion and having a flow control layer with a port and a plurality of flow holes in the seat portion, a spacer, a fluid barrier and at least one conduit with a plurality of flow holes located adjacent to the seat portion of the flow control layer. The seat also may include a fan in fluid communication with the spacer and a fluid conditioning device.

Abstract: The present invention relates to a ventilated seat having an insert with a seat portion, and having a flow control layer with first and second ports, a spacer having an inlay and a main portion, and a first fluid barrier where the inlay is substantially isolated from the main portion by a fluid-tight boundary. The present invention also relates to a ventilated seat having an insert with a seat portion and having a first flow control layer with at least one port, a first and a second spacer, and a fluid barrier comprising at least one port. The present invention also relates to a ventilated seat with an insert having a seat portion and having a flow control layer with a port and a plurality of flow holes in the seat portion, a spacer, a fluid barrier and at least one conduit with a plurality of flow holes located adjacent to the seat portion of the flow control layer. The seat also may include a fan in fluid communication with the spacer and a fluid conditioning device.

Abstract: The present invention is directed towards a method of forming a ventilated seat. More specifically, in one aspect, the present invention is directed towards providing an insert in fluid communications with an air mover and a seating surface, wherein the system optionally includes a thermoelectric device for providing heating or cooling of air flowing through the insert.

Abstract: The present invention relates to a ventilated seat having an insert with a seat portion, and having a flow control layer with first and second ports, a spacer having an inlay and a main portion, and a first fluid barrier where the inlay is substantially isolated from the main portion by a fluid-tight boundary. The present invention also relates to a ventilated seat having an insert with a seat portion and having a first flow control layer with at least one port, a first and a second spacer, and a fluid barrier comprising at least one port. The present invention also relates to a ventilated seat with an insert having a seat portion and having a flow control layer with a port and a plurality of flow holes in the seat portion, a spacer, a fluid barrier and at least one conduit with a plurality of flow holes located adjacent to the seat portion of the flow control layer. The seat also may include a fan in fluid communication with the spacer and a fluid conditioning device.

Abstract: The invention relates to a heating element (20), in particular for heating user contact surfaces of a passenger compartment of a vehicle, comprising at least one heating area (100) wherein at least one electric conductor strand (1), which is used to heat, is arranged, at least one additional conductor strand (2) which is used to feed electric energy into at least one conductor strand (1) which is used to heat the heating area (100), at least one contact area (200) wherein the conductor strand (2), which is used to feed electric energy, is connected in an electrically conductive manner to the at least one conductor strand (1) which is used to heat the heating area (100). According to the invention, at least one additional conductor (3) which forms at least one part of an electrically bridging line which bridges the failure point on a failure point during local failures of at least one of the conductor strands (1, 2), is provided.

Abstract: The present invention relates to a ventilated seat having an insert with a seat portion, and having a flow control layer with first and second ports, a spacer having an inlay and a main portion, and a first fluid barrier where the inlay is substantially isolated from the main portion by a fluid-tight boundary. The present invention also relates to a ventilated seat having an insert with a seat portion and having a first flow control layer with at least one port, a first and a second spacer, and a fluid barrier comprising at least one port. The present invention also relates to a ventilated seat with an insert having a seat portion and having a flow control layer with a port and a plurality of flow holes in the seat portion, a spacer, a fluid barrier and at least one conduit with a plurality of flow holes located adjacent to the seat portion of the flow control layer. The seat also may include a fan in fluid communication with the spacer and a fluid conditioning device.

Abstract: The present invention relates to a ventilated seat having an insert with a seat portion, and having a flow control layer with first and second ports, a spacer having an inlay and a main portion, and a first fluid barrier where the inlay is substantially isolated from the main portion by a fluid-tight boundary. The present invention also relates to a ventilated seat having an insert with a seat portion and having a first flow control layer with at least one port, a first and a second spacer, and a fluid barrier comprising at least one port. The present invention also relates to a ventilated seat with an insert having a seat portion and having a flow control layer with a port and a plurality of flow holes in the seat portion, a spacer, a fluid barrier and at least one conduit with a plurality of flow holes located adjacent to the seat portion of the flow control layer. The seat also may include a fan in fluid communication with the spacer and a fluid conditioning device.