Abstract: The present invention relates to a peptide having the sequence from N-terminus to C-terminus X-2X-1ZX1X2X3X4X5 wherein Z is tyrosine, phosphotyrosine or a non-natural analogue of phosphotyrosine, such as phosphonodifluoromethyl phenylalanine (F2Pmp) X-2 is a hydrophobic amino acid, such as Leu, Ile, Val, Phe, Tyr, Trp and Met X-1 is any amino acid X1 is a hydrophobic amino acid, such as Ile, Leu, Val, Phe, Tyr, Trp and Met X3 is a hydrophobic amino acid, such as Leu, Ile, Val, Phe, Tyr, Trp and Met X5 is a hydrophobic amino acid, such as Trp, Ile, Val, Phe, Tyr, and Met X2 and X4 are anionic amino acids, preferably each independently is Asp or Glu. The peptide inhibits protein-protein interactions of the Src homology 2 domain-containing phosphatase 2 (SHP2), for the treatment of cancer and RASopathies and as a biomedical research tool.

Abstract: The electric motorcycle (M) comprises a support frame, a rear wheel (RW), a front wheel (FW), an electric propulsion motor (E), an electronic control unit (2) for driving the electric motor (E) and a wheel anti-lock system (1) operatively connected to the control unit (2), the system (1) having detection means (18) of a slippage condition (SLP) of at least one of the wheels (RW, FW) and limiting means (19) operatively connected to the detecting means (18), able to receive at input at least a maximum regeneration torque value (RTMAX) of the electric motor (E) of the electric motorcycle (M) and able to limit the maximum regeneration torque (RTMAX) in case of detection of the slippage condition (SLP), wherein the system (1) comprises verification means (20) of the friction conditions of the wheels (RW, FW) on the road surface, in order to verify the presence or not of a high friction condition (HIGH_MU) or a low friction condition (LOW_MU), wherein the limiting means (19) are operatively connected to the verific

Abstract: The system (1) for piloting an electric motor in electric motorcycles or the like is operatively connectable to a control inverter (I) of an electric motor (E) of an electric motorcycle (M) and to a control device (C) of the acceleration of the electric motorcycle (M) and comprises dynamic generation means (10) of a piloting signal (TOUT) of the inverter (I) according to a control signal (G) coming from the control device (C) and to at least a maximum deliverable/absorbable current value (IMAX, RIMAX) by an electric battery (B) of the electric motorcycle (M).

Abstract: The electric motorcycle (M) comprises a support frame, a rear wheel (RW), a front wheel (FW), an electric propulsion motor (E), an electronic control unit (2) for driving the electric motor (E) and a wheel anti-lock system (1) operatively connected to the control unit (2), the system (1) having detection means (18) of a slippage condition (SLP) of at least one of the wheels (RW, FW) and limiting means (19) operatively connected to the detecting means (18), able to receive at input at least a maximum regeneration torque value (RTMAX) of the electric motor (E) of the electric motorcycle (M) and able to limit the maximum regeneration torque (RTMAX) in case of detection of the slippage condition (SLP), wherein the system (1) comprises verification means (20) of the friction conditions of the wheels (RW, FW) on the road surface, in order to verify the presence or not of a high friction condition (HIGH_MU) or a low friction condition (LOW_MU), wherein the limiting means (19) are operatively connected to the verific

Abstract: The system (1) for piloting an electric motor in electric motorcycles or the like is operatively connectable to a control inverter (I) of an electric motor (E) of an electric motorcycle (M) and to a control device (C) of the acceleration of the electric motorcycle (M) and comprises dynamic generation means (10) of a piloting signal (TOUT) of the inverter (I) according to a control signal (G) coming from the control device (C) and to at least a maximum deliverable/absorbable current value (IMAX, RIMAX) by an electric battery (B) of the electric motorcycle (M).