Patents by Inventor Simone Proemel

Simone Proemel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100310521
    Abstract: A DNA polynucleotide sequence is disclosed that comprises a transcribed sequence, and a promoter sequence. Transcription of the transcribed sequence by an RNA polymerase in a cell renders an RNA a transcript capable of forming a partially self-complementary hairpin structure which can be processed by the cell to an siRNA product that can degrade phospholamban mRNA in such cell. The promoter is a drug inducible conditional promoter or a cardiomyocyte cell-specific promoter or both, operably linked to the transcribed sequence. The promoter is operable by an RNA polymerase naturally occurring in a mammalian cell.
    Type: Application
    Filed: December 28, 2007
    Publication date: December 9, 2010
    Applicants: CHARITE - UNIVERSITAETSMEDIZIN BERLIN, FREIE UNIVERSITAET BERLIN
    Inventors: Henry Fechner, Jens Kurreck, Simone Proemel