Patents by Inventor Simone Sell

Simone Sell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190367921
    Abstract: The present invention is related to a method for generating a nucleic acid molecule capable of binding to a target molecule comprising the following steps: a) providing a reference nucleic acid molecule, wherein the reference nucleic acid molecule is capable of binding to the target molecule and wherein the reference nucleic acid molecule comprises a sequence of nucleotides, wherein the sequence of nucleotides comprises n nucleotides; b) preparing a first level derivative of the reference nucleic acid molecule, wherein the first level derivative of the reference nucleic acid molecule differs from the reference nucleic acid molecule at one nucleotide position, wherein the first level derivative is prepared by replacing the ribonucleotide at the one nucleotide position by a 2?-deoxyribonucleotide in case the reference nucleic acid has a ribonucleotide at the nucleotide position and wherein the first level derivative is prepared by replacing the 2?-deoxyribonucleotide at the one nucleotide position by a ribonucl
    Type: Application
    Filed: May 21, 2018
    Publication date: December 5, 2019
    Inventors: Florian Jarosch, Sven Klussmann, Simone Sell, Werner Purschke, Christian Maasch, Axel Vater, Kai Hohlig
  • Patent number: 9976145
    Abstract: The present invention is related to a method for generating a nucleic acid molecule capable of binding to a target molecule comprising the following steps: a) providing a reference nucleic acid molecule, wherein the reference nucleic acid molecule is capable of binding to the target molecule and wherein the reference nucleic acid molecule comprises a sequence of nucleotides, wherein the sequence of nucleotides comprises n nucleotides; b) preparing a first level derivative of the reference nucleic acid molecule, wherein the first level derivative of the reference nucleic acid molecule differs from the reference nucleic acid molecule at one nucleotide position, wherein the first level derivative is prepared by replacing the ribonucleotide at the one nucleotide position by a 2?-deoxyribonucleotide in case the reference nucleic acid has a ribonucleotide at the nucleotide position and wherein the first level derivative is prepared by replacing the 2?-deoxyribonucleotide at the one nucleotide position by a ribonucl
    Type: Grant
    Filed: January 10, 2012
    Date of Patent: May 22, 2018
    Assignee: NOXXON Pharma AG
    Inventors: Florian Jarosch, Sven Klussmann, Simone Sell, Werner Purschke, Christian Maasch, Axel Vater, Kai Hohlig
  • Publication number: 20160257958
    Abstract: The present invention is related to a nucleic acid capable of binding to hepcidin.
    Type: Application
    Filed: September 23, 2014
    Publication date: September 8, 2016
    Inventors: Simone Sell, Frank Morich, Christian Maasch, Sven Klussmann, Nicole Dinse, Klaus Buchner, Frank Schwobel
  • Publication number: 20150232852
    Abstract: The present invention is related to a nucleic acid molecule capable of binding to a target molecule, wherein the nucleic acid molecule has a binding affinity to the target molecule, wherein the binding affinity of the nucleic acid molecule to the target molecule is increased or the same compared to the binding affinity of a reference nucleic acid molecule to the target molecule, wherein a) the nucleic acid molecule comprises a sequence of nucleotides and the reference nucleic acid molecule comprises a sequence of nucleotides, or b) the nucleic acid molecule comprises a sequence of nucleotides and at least one modification group and the reference nucleic acid molecule comprises a sequence of nucleotides and the at least one modification group, wherein the sequence of nucleotides of the nucleic acid molecule and the sequence of nucleotides of the reference nucleic acid molecule are at least partially identical with respect to the nucleobase moiety of the nucleotides but differ with respect to the sugar moie
    Type: Application
    Filed: October 22, 2012
    Publication date: August 20, 2015
    Inventors: Werner Purschke, Simone Sell, Axel Vater, Klaus Buchner, Christian Maasch, Sven Klussmann
  • Publication number: 20140350088
    Abstract: The present invention is related to a method for generating a nucleic acid molecule capable of binding to a target molecule comprising the following steps: a) providing a reference nucleic acid molecule, wherein the reference nucleic acid molecule is capable of binding to the target molecule and wherein the reference nucleic acid molecule comprises a sequence of nucleotides, wherein the sequence of nucleotides comprises n nucleotides; b) preparing a first level derivative of the reference nucleic acid molecule, wherein the first level derivative of the reference nucleic acid molecule differs from the reference nucleic acid molecule at one nucleotide position, wherein the first level derivative is prepared by replacing the ribonucleotide at the one nucleotide position by a 2?-deoxyribonucleotide in case the reference nucleic acid has a ribonucleotide at the nucleotide position and wherein the first level derivative is prepared by replacing the 2?-deoxyribonucleotide at the one nucleotide position by a ribonucl
    Type: Application
    Filed: January 10, 2012
    Publication date: November 27, 2014
    Inventors: Florian Jarosch, Sven Klussmann, Simone Sell, Werner Purschke, Christian Maasch, Axel Vater, Kai Hohlig
  • Patent number: 8841431
    Abstract: The present invention is related to a nucleic acid capable of binding to hepcidin.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: September 23, 2014
    Assignee: NOXXON Pharma AG
    Inventors: Simone Sell, Frank Morich, Christian Maasch, Sven Klussmann, Nicole Dinse, Klaus Buchner, Frank Schwobel
  • Publication number: 20120053234
    Abstract: The present invention is related to a nucleic acid capable of binding to hepcidin.
    Type: Application
    Filed: April 30, 2010
    Publication date: March 1, 2012
    Applicant: NOXXON PHARMA AG
    Inventors: Simone Sell, Frank Morich, Christian Maasch, Sven Klussmann, Nicole Dinse, Klaus Buchner, Frank Schwobel