Patents by Inventor Simone Thierfelder

Simone Thierfelder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Device and Method for Detecting a Substance by Means of Particle Plasmon Resonance (PPR) or Particle-Mediated Fluorescence Based on Cell Surface Polarizations
    Publication number: 20100285505
    Abstract: The invention relates to devices and methods for detecting a substance by cell surface polarizations and the detection thereof by means of PPR or particle-mediated fluorescence. The device for detecting a substance by cell surface polarization according to the invention has cells, wherein a gene the expression of which leads to the polarized presentation of a protein on the surface of the cell is placed under the control of a promotor which can be regulated by the substance to be detected, nanoparticles which are functionalized with a molecule which can bind specifically to the surface-exposed protein, and at least one optical measurement device, such that an accumulation of the nanoparticles on the surface of the cells can be detected by particle plasmon resonance or particle-mediated fluorescence.
    Type: Application
    Filed: June 27, 2008
    Publication date: November 11, 2010
    Applicant: TECHNISCHE UNIVERSITAET DRESDEN
    Inventors: Kai Ostermann, Wolfgang Pompe, Dagmar Wersing, Mathias Lakatos, Michael Mertig, Gerhard Rödel, Simone Thierfelder