Patents by Inventor Sinead Kinsella

Sinead Kinsella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS TO PROMOTE THYMIC FUNCTION
    Publication number: 20230263800
    Abstract: Compositions and methods to promote thymic function are described. The compositions and methods can activate the GPR39 receptor and/or a purinergic receptor, such as P2Y2. The activation can upregulate regenerative molecules, such as FOXN1, interleukin (IL)-22, IL-23, and bone morphogenetic protein 4 (BMP4).
    Type: Application
    Filed: November 3, 2021
    Publication date: August 24, 2023
    Applicant: Fred Hutchinson Cancer Center
    Inventors: Jarrod Dudakov, Sinead Kinsella, Lorenzo Iovino
  • COMPOSITIONS AND METHODS TO PROMOTE THYMIC REGENERATION
    Publication number: 20210113573
    Abstract: Methods to promote thymic regeneration are described. The methods can inhibit nucleotide-binding oligomerization domain-containing protein 2 (NOD2), Rho GTPases, and/or microRNA 29c (miR29c). These inhibition methods can promote regenerative molecules, such as interleukin (IL)-22, IL-23, and/or bone morphogenetic protein 4 (BMP4). Promoting thymic regeneration can be beneficial in patients due to age, infection, or cancer therapies.
    Type: Application
    Filed: January 11, 2019
    Publication date: April 22, 2021
    Applicant: FRED HUTCHINSON CANCER RESEARCH CENTER
    Inventors: Jarrod Dudakov, Sinead Kinsella