Patents by Inventor Sing Yeung Frankie Mak

Sing Yeung Frankie Mak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • QUINOLINE COMPOUNDS AND COMPOSITIONS FOR INHIBITING EZH2
    Publication number: 20230167100
    Abstract: The invention disclosed herein relates to aza-quinoline compounds of Formula (I), pharmaceutical compositions comprising such compounds, and the use of such compounds for treating a disease or condition mediated by Enhancer of Zeste Homolog 2 (EZH2), Polycomb Repressive Complex 2 (PRC2), or a combination thereof.
    Type: Application
    Filed: August 10, 2021
    Publication date: June 1, 2023
    Inventors: Xuan DAI, Michael DORE, Xiang-Ju Justin GU, Ling LI, Kun Chin LIU, Sing Yeung Frankie MAK, Yuan MI, Counde OYANG, Julien PAPILLON, Wei (Vicky) QI, Xiaoxia YAN, Zhengtian YU, Ji Yue (Jeff) ZHANG, Kehao ZHAO
  • PROCESS OF PREPARING ARACHIDONOYLETHANOLAMINE ANALOGUES
    Publication number: 20230064920
    Abstract: The present application provides new processes for preparing arachidonoylethanolamine analogues. Intermediates useful for preparing the compounds are also provided.
    Type: Application
    Filed: November 20, 2020
    Publication date: March 2, 2023
    Applicant: TRAVECTA THERAPEUTICS PTE. LTD.
    Inventors: Mahmood AHMED, Sing Yeung Frankie MAK, Ravi Kumar PUTHUKANOORI, Sampath Kumar NANGUNOORI, Ramana Murthy Venkata APPALA, Narendar VENNU, Filippo ROMOLI, Giovanni MARRAS
  • HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS
    Publication number: 20220289732
    Abstract: The present invention provides compounds of Formula (I) or a pharmaceutically acceptable salt thereof; (I) which are inhibitors of WDR5. The present invention also provides pharmaceutical compositions comprising such compounds, compositions comprising such compounds with an additional therapeutic agent and the therapeutic uses of such compounds.
    Type: Application
    Filed: August 7, 2020
    Publication date: September 15, 2022
    Inventors: Lichao FANG, Zhenting GAO, Xiangqing JIANG, Kevin Kun Chin LIU, Sing Yeung Frankie MAK, Counde OYANG, Ce WANG, Tao WANG, Jianping WU, Wu YINGMING, Qitao XIAO
  • AZA-QUINOLINE COMPOUNDS AND USES THEREOF
    Publication number: 20220280509
    Abstract: Provided aza-quinoline compounds of Formula (I), pharmaceutical compositions comprising such compounds; and the use of such compounds for treating a disease or condition mediate by Enhancer of Zeste Homolog 2 (EZH2), Polycomb Repressive Complex 2 (PRC2), or a combination thereof.
    Type: Application
    Filed: September 24, 2020
    Publication date: September 8, 2022
    Inventors: Ling LI, Xuan DAI, Michael DORE, Xiang-Ju Justin GU, Kevin Kun Chin LIU, Sing Yeung Frankie MAK, Yuan MI, Counde OYANG, Julien PAPILLON, Wei (Vicky) QI, Xiaoxia YAN, Zhengtian YU, Ji Yue (Jeff) ZHANG, Kehao ZHAO
  • ANANDAMIDE COMPOUNDS
    Publication number: 20220112225
    Abstract: The present application provides anandamide and 2-arachidonoyl glycerol compounds useful for treating a disease or disorder in a subject in need thereof. Pharmaceutical compositions comprising the compounds and methods of treating diseases or disorders are also provided.
    Type: Application
    Filed: January 10, 2020
    Publication date: April 14, 2022
    Inventors: David Lawrence Silver, Mahmood Ahmed, Sing Yeung Frankie Mak