Patents by Inventor Sing-Ying Hsieh

Sing-Ying Hsieh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11254902
    Abstract: A cell culture module, a cell culture system and a cell culture method are provided. The cell culture module includes a casing, a first fixer, a second fixer and a sheet-shaped carrier member. The casing has a chamber and at least one inlet/outlet. The inlet/outlet communicates with the chamber. The first fixer is fixed to the casing and located in the chamber. The second fixer is disposed in the chamber and is movable relative to the first fixer. The sheet-shaped carrier member is formed by arranging a plurality of cell culture carriers, and two opposite ends of the sheet-shaped carrier member are respectively fixed to the first fixer and the second fixer. The sheet-shaped carrier member is in an open state or a folded state according to a variation in a distance between the first fixer and the second fixer due to a movement of the second fixer.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: February 22, 2022
    Assignee: Industrial Technology Research Institute
    Inventors: Ing-Kae Wang, Ying-Wen Shen, Yea-Tzy Deng, Den-Tai Lin, Yu-Bing Liou, Sing-Ying Hsieh, Wei-Zhou Yeh, Meng-Hua Yang, Hsiang-Chun Hsu, Ying-Chun Chien
  • Patent number: 10704017
    Abstract: A cell culture carrier module and a cell culture system having the same are provided. A cell tank and a culture medium module respectively communicate with the carrier module. The carrier module includes a reactor, a first fixer, a second fixer and a plurality of cell culture carriers. The reactor has a chamber and at least one inlet/outlet. The inlet/outlet communicates with the chamber. The first fixer is fixed to the reactor and located in the chamber. The second fixer is disposed in the chamber and is movable relative to the first fixer. Two ends of each cell culture carrier are fixed to the first fixer and the second fixer, respectively. The cell culture carriers are in an untwisted state or a twisted state according to a variation in a distance between the first fixer and the second fixer due to a movement of the second fixer.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: July 7, 2020
    Assignee: Industrial Technology Research Institute
    Inventors: Ying-Wen Shen, Ing-Kae Wang, Chia-Jung Lu, Yea-Tzy Deng, Yu-Bing Liou, Sing-Ying Hsieh, Hsin-Hsin Shen, Hsiu-Ying Wang
  • Publication number: 20190203165
    Abstract: A cell culture module, a cell culture system and a cell culture method are provided. The cell culture module includes a casing, a first fixer, a second fixer and a sheet-shaped carrier member. The casing has a chamber and at least one inlet/outlet. The inlet/outlet communicates with the chamber. The first fixer is fixed to the casing and located in the chamber. The second fixer is disposed in the chamber and is movable relative to the first fixer. The sheet-shaped carrier member is formed by arranging a plurality of cell culture carriers, and two opposite ends of the sheet-shaped carrier member are respectively fixed to the first fixer and the second fixer. The sheet-shaped carrier member is in an open state or a folded state according to a variation in a distance between the first fixer and the second fixer due to a movement of the second fixer.
    Type: Application
    Filed: December 20, 2018
    Publication date: July 4, 2019
    Applicant: Industrial Technology Research Institute
    Inventors: Ing-Kae Wang, Ying-Wen Shen, Yea-Tzy Deng, Den-Tai Lin, Yu-Bing Liou, Sing-Ying Hsieh, Wei-Zhou Yeh, Meng-Hua Yang, Hsiang-Chun Hsu, Ying-Chun Chien
  • Publication number: 20180223238
    Abstract: A cell culture carrier module and a cell culture system having the same are provided. A cell tank and a culture medium module respectively communicate with the carrier module. The carrier module includes a reactor, a first fixer, a second fixer and a plurality of cell culture carriers. The reactor has a chamber and at least one inlet/outlet. The inlet/outlet communicates with the chamber. The first fixer is fixed to the reactor and located in the chamber. The second fixer is disposed in the chamber and is movable relative to the first fixer. Two ends of each cell culture carrier are fixed to the first fixer and the second fixer, respectively. The cell culture carriers are in an untwisted state or a twisted state according to a variation in a distance between the first fixer and the second fixer due to a movement of the second fixer.
    Type: Application
    Filed: December 27, 2017
    Publication date: August 9, 2018
    Applicant: Industrial Technology Research Institute
    Inventors: Ying-Wen Shen, Ing-Kae Wang, Chia-Jung Lu, Yea-Tzy Deng, Yu-Bing Liou, Sing-Ying Hsieh, Hsin-Hsin Shen, Hsiu-Ying Wang
  • Publication number: 20060292690
    Abstract: The present invention discloses a three-dimensional porous growth surface made from polysaccharide material, especially the alginic acid, to enhance cell growth surface, promote cell adherence, immobilization and propagation, maintain surface structure integrity, enable programmable degradation, and thus increase cellular production. The present invention teaches several methods: a method to enhance the integrity of the growth surface by protecting the growth surface in a rigid solid support; a method of use for enhancing the performance of the surface; and a method of modifying a growth surface for eukaryotic and/or prokaryotic cells comprising the steps of increasing surface area by creating porous and 3-D structure, treating a surface to encourage cell attachment, promoting cell growth and proliferation, and disposing the growth surface in any conventional cell cultivating device. The growth surface is able to program degradation and release the cell/tissue mass after the culture is completed.
    Type: Application
    Filed: June 21, 2006
    Publication date: December 28, 2006
    Inventors: Tzu-Ying Liu, Ing-Kae Wang, Sing-Ying Hsieh, Lewis Ho, Yu-Chi Wang, King-Ming Chang