Patents by Inventor Siobhan Roche

Siobhan Roche has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RORS as modifiers of the p21 pathway and methods of use
    Patent number: 8426147
    Abstract: Human ROR genes are identified as modulators of the p21 pathway, and thus are therapeutic targets for disorders associated with defective p21 function. Methods for identifying modulators of p21, comprising screening for agents that modulate the activity of ROR are provided.
    Type: Grant
    Filed: December 1, 2008
    Date of Patent: April 23, 2013
    Assignee: Exelixis, Inc.
    Inventors: Helen Francis-Lang, Lori Friedman, Thomas Kidd, Siobhan Roche, Haiguang Zhang
  • PAKs as Modifiers of the CHK Pathway and Methods of Use
    Publication number: 20110059066
    Abstract: Human PAK genes are identified as modulators of the CHK pathway, and thus are therapeutic targets for disorders associated with defective CHK function. Methods for identifying modulators of CHK, comprising screening for agents that modulate the activity of PAK are provided.
    Type: Application
    Filed: July 1, 2010
    Publication date: March 10, 2011
    Applicant: EXELIXIS, INC.
    Inventors: Helen Francis-Lang, Siobhan Roche, Lickteig Kim
  • RORS as Modifiers of the p21 Pathway and Methods of Use
    Publication number: 20090149413
    Abstract: Human ROR genes are identified as modulators of the p21 pathway, and thus are therapeutic targets for disorders associated with defective p21 function. Methods for identifying modulators of p21, comprising screening for agents that modulate the activity of ROR are provided.
    Type: Application
    Filed: December 1, 2008
    Publication date: June 11, 2009
    Applicant: EXELIXIS INC.
    Inventors: Helen Francis-Lang, Lori Friedman, Thomas Kidd, Siobhan Roche, Haiguang Zhang
  • Gpcs as modifiers of the irrtk p21 pathways and methods of use
    Publication number: 20060121041
    Abstract: Human GPC genes are identified as modulators of the IRRTK or p21 pathways, and thus are therapeutic targets for disorders associated with defective IRRTK or p21 function. Methods for identifying modulators of IRRTK or p21, comprising screening for agents that modulate the activity of GPC are provided.
    Type: Application
    Filed: July 10, 2002
    Publication date: June 8, 2006
    Inventors: Lori Friedman, Gregory Plowman, Tom Kidd, Roel Funke, Danxi Li, Siobhan Roche
  • Paks as modifiers of the chk pathway and methods of use
    Publication number: 20060123498
    Abstract: Human PAK genes are identified as modulators of the CHK pathway, and thus are therapeutic targets for disorders associated with defective CHK function. Methods for identifying modulators of CHK, comprising screening for agents that modulate the activity of PAK are provided.
    Type: Application
    Filed: September 15, 2003
    Publication date: June 8, 2006
    Inventors: Helen Francis-Lang, Siobhan Roche, Lickteig Kim
  • Rors as modifiers of the p21 pathway and methods of use
    Publication number: 20060101530
    Abstract: Human ROR genes are identified as modulators of the p21 pathway, and thus are therapeutic targets for disorders associated with defective p21 function. Methods for identifying modulators of p21, comprising screening for agents that modulate the activity of ROR are provided.
    Type: Application
    Filed: September 15, 2003
    Publication date: May 11, 2006
    Inventors: Helen Francis-Lang, Lori Friedman, Thomas Kidd, Siobhan Roche, Haiquang Zhang